Transcript IWORID 2002
Flat X-ray Detectors for Medical Imaging Michael Overdick Philips Research Laboratories, Aachen, Germany IWORID 2002, Amsterdam, 11 Sept. 2002 Outline • Flat Detector Technology – Overview – Key Components • FD Performance • Imaging Examples • History & Future PFL-Aachen, M. Overdick, 11 Sept 2002, IWORID 2002 2 Flat Detector Technology Scintillator ADC Readout PFL-Aachen, M. Overdick, 11 Sept 2002, IWORID 2002 Addressing 3 Static detector: Digital Diagnost PFL-Aachen, M. Overdick, 11 Sept 2002, IWORID 2002 4 Dynamic detector: Integris Allura PFL-Aachen, M. Overdick, 11 Sept 2002, IWORID 2002 5 Scintillator: CsI:Tl needle crystals • Thickness 550µm good X-ray absorption • Needles act as light-guides sharp MTF • CsI:Tl emits green light PFL-Aachen, M. Overdick, 11 Sept 2002, IWORID 2002 6 Photodiode array: a-Si technology • Same technology as used in active matrix LCDs (TFT displays) • a-Si photodiodes: low dark currents, high sensitivity for green light PFL-Aachen, M. Overdick, 11 Sept 2002, IWORID 2002 7 Low noise readout electronics • Driver and readout chips on flex modules 20 cm PFL-Aachen, M. Overdick, 11 Sept 2002, IWORID 2002 • Allowing very compact designs 8 Main noise sources in Flat X-ray Detectors Shot noise from the photodiode (incl. refresh light) TFT switch Gate line Photodiode Common electrode Pixel circuit of dynamic FD Column read-out line CSA 300 e- Switching noise (kTC-noise) 750 e- Amplifier noise 800 e- other (TFT etc.) 600 e- “Electronic noise” PFL-Aachen, M. Overdick, 11 Sept 2002, IWORID 2002 approx. ENC 1300 e- X-ray quantum noise! 9 Integris Allura Flat Dynamic Detector for Cardio Scintillator PFL-Aachen, M. Overdick, 11 Sept 2002, IWORID 2002 Photodiode array Refresh light 10 Technical Data Digital Diagnost Integris Allura FD Detection static Field of view 43 cm x 43 cm static + dynamic (up to 30 frames/s) 18 cm x 18 cm Number of pixels 3k x 3k 1k x 1k Pixel size 143 µm x 143 µm 184 µm x 184 µm DQE(0) 60 % PFL-Aachen, M. Overdick, 11 Sept 2002, IWORID 2002 75 % 11 Detective Quantum Efficiency (DQE) for a Flat Dynamic Detector 1 0.9 1000nGy 0.8 100nGy 10nGy 0.7 5nGy DQE 0.6 0.5 0.4 0.3 0.2 0.1 0 0 0.5 1 1.5 2 2.5 -1 frequency [mm ] From: F. Busse et al., Proc. SPIE 4320 (2001) 287-298 PFL-Aachen, M. Overdick, 11 Sept 2002, IWORID 2002 12 DQE for a Static Flat Detector DQE 0.8 Screen-film (400) Fuji ST type V Flat-panel detector 0.6 0.4 0.2 0 0 1 2 3 4 lp/mm Source: PMS Hamburg PFL-Aachen, M. Overdick, 11 Sept 2002, IWORID 2002 13 Static FD performance vs. Screen/Film systems • • • • High DQE Fully digital Simple handling (no cassettes or films) Large dynamic range PFL-Aachen, M. Overdick, 11 Sept 2002, IWORID 2002 14 X-ray film: Dynamic range 0.5 mAs 2 mAs 4 mAs Under-exposed PFL-Aachen, M. Overdick, 11 Sept 2002, IWORID 2002 8 mAs 16 mAs 32 mAs 63 mAs Over-exposed 15 Flat detector: Dynamic range typical usage PFL-Aachen, M. Overdick, 11 Sept 2002, IWORID 2002 16 Dynamic FD performance vs. Image intensifiers (II-TV systems) • • • • • Larger dynamic range Size & weight Undistorted images Immune to magnetic fields Strongly reduced: Veiling glare and fixed pattern noise PFL-Aachen, M. Overdick, 11 Sept 2002, IWORID 2002 17 Imaging examples Dynamic FD: Heart arteries with contrast agent PFL-Aachen, M. Overdick, 11 Sept 2002, IWORID 2002 18 Imaging examples Static FD: Shoulder and finger 1 cm PFL-Aachen, M. Overdick, 11 Sept 2002, IWORID 2002 19 History 1989 1993 1997 2000 2001 Start of FD Research Project at Philips 8”x8” FD Prototype Joint venture with Thomson and Siemens (Trixell) Introduction of static FDs by Trixell and GE Medical Introduction of dynamic FDs for Cardio application (GE Medical and Trixell) Apart from CsI:Tl based FDs also Selenium based FDs are availble (e.g. from Anrad/Toshiba), mainly used for static applications (e.g. mammography). PFL-Aachen, M. Overdick, 11 Sept 2002, IWORID 2002 20 Future • Flat Detectors for further applications and with different sizes will enter the market. • FDs will gradually replace II-TV systems. PFL-Aachen, M. Overdick, 11 Sept 2002, IWORID 2002 21 And what about CMOS Pixels? CMOS Pixel Electronics + Amplifier in each pixel + Additional functionality But: • Cost and feasibility of large area CMOS coverage! • Please carefully check against FD performance (as the new “gold standard”) Counting vs. Integrating: • Nice topic for an extra talk! • Observe the high maximal count rates ( 109 counts/s mm²) PFL-Aachen, M. Overdick, 11 Sept 2002, IWORID 2002 22 Conclusions • Flat Detectors are out now in the market (mainly static detectors and cardio detectors) • FD technology offers various benefits as compared to conventional systems. • Scintillator, a-Si technology and low noise electronics are the key FD ingredients. • New X-ray detector developments should use FD performance as their new benchmark. PFL-Aachen, M. Overdick, 11 Sept 2002, IWORID 2002 23 Acknowledgements • Philips Medical Systems (Best, Hamburg and North America) • Trixell (Moirans, France) • Colleagues at Philips Research Aachen and Redhill PFL-Aachen, M. Overdick, 11 Sept 2002, IWORID 2002 24 Residual signals 10 10 10 Normalized residual signal @ 21x30µGy Normalized residual signal @ 30µGy Dependence on the Refresh Light Duration -2 -3 RLD=0µs g= -0.92 RLD=10µs g= -1.06 RLD=50µs g= -1.24 -4 10 -1 0 10 Time in s after exposure 10 1 10 10 10 -2 -3 RLD=0µs g= -0.74 RLD=10µs g= -0.77 RLD=50µs g= -0.83 RLD=250µs g= -0.89 -4 10 -1 0 10 Time in s after last exposure 10 1 Stronger refresh light accelerates decay of Res. Signals (M. Overdick et al., Proc. SPIE 4320 (2001) 47-58) PFL-Aachen, M. Overdick, 11 Sept 2002, IWORID 2002 26