Transcript The Eye in Systemic Disease

The Eye in
Systemic Disease
The Eye in Systemic Disease
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●
Numerous conditions have eye symptoms
associated with them
Different parts of the eye are associated with
different syndrome
The Eye in Systemic Disease
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Structure of Talk:
–
Mind Map
Amauros
is
Fugax
Retinal
vessel
disease
Pupillary
Abnormali
ties
Cataracts
Eye
CRAO
Uveitis
Abnorm
Eye
Moveme
nts
Common Eye Problems
Cataracts
Eye
Metaboli
c
CATARACTS
Other
Systemic
Diseases
Drug
Induced
DM
G6P
D
Metabolic
PFK
D
CATARACTS
Metaboli
c
CATARACTS
Muscular
Dystroph
y
Dermatitis
Other
Systemic
Diseases
NF 2
Metaboli
c
CATARACTS
Steroids
Other
Systemic
Diseases
Drug
Induced
Common Eye Problems
Amauros
is
Fugax
Retinal
vessel
disease
Pupillary
Abnormali
ties
Cataracts
Eye
CRAO
Uveitis
Abnorm
Eye
Moveme
nts
Common Eye Problems
Eye
Uveitis
Systemic Dis
&
Syndromes
Uveitis
Infections
Infestations
Systemic Dis
&
Syndromes
Uveitis
Reiter's
Behce
ts
Sarcoi
d
Ank
Spond
Systemic
Dis
&
Syndromes
Crohn's
Dis
Uveitis
UC
JCA
Reiter's
Behce
ts
Sarcoi
d
Ank
Spond
Systemic
Dis
&
Syndromes
Crohn's
Dis
Uveitis
UC
JCA
Polyarthritis
Reiter's
Behce
ts
Sarcoi
d
Ank
Spond
Systemic
Dis
&
Syndromes
Crohn's
Dis
Uveitis
UC
JCA
Reiter's
Behce
ts
Sarcoi
d
Ank
Spond
Crohn's
Dis
Systemic
Dis
&
Syndromes
Uveitis
UC
JCA
Sacroiliitis
(also
spine)
Reiter's
Behcets
Sarcoid
Ank
Spond
Systemic
Dis
&
Syndromes
Crohn's
Dis
Uveitis
UC
JCA
Urethritis
Arthritis
Reiter's
Behce
ts
Sarcoi
d
Ank
Spond
Systemic
Dis
&
Syndromes
Crohn's
Dis
Uveitis
UC
JCA
Overreaction of
Immune System
Reiter's
Behce
ts
Sarcoi
d
Ank
Spond
Systemic
Dis
&
Syndromes
Crohn's
Dis
Uveitis
UC
JCA
oral ulcers
Reiter's
Genital
ulcers
Skin
Lesions
Behcets
Sarcoi
d
Ank
Spond
Systemic
Dis
&
Syndromes
Crohn's
Dis
Uveitis
UC
JCA
Behce
ts
Reiter's
Granulomas
Sarcoi
d
Ank
Spond
Systemic
Dis
&
Syndromes
Crohn's
Dis
Unknown
Aetiology
Uveitis
UC
JCA
Behce
ts
Reiter's
Sarcoi
d
Ank
Spond
Systemic
Dis
&
Syndromes
Crohn's
Dis
Uveitis
UC
JCA
Systemic
Dis
&
Syndrome
s
Uveitis
Infections
Infestations
Uveitis
Infections
TB
Infections
Candida
Herpes
Zoster
Systemic
Dis
&
Syndrome
s
Uveitis
Infections
Infestations
Uveitis
Infestations
Toxoplasm
osis
Infestations
Toxocariasi
s
Pneumocyst
osis
Common Eye Problems
Amauros
is
Fugax
Retinal
vessel
disease
Pupillary
Abnormali
ties
Cataracts
Eye
CRAO
Uveitis
Abnorm
Eye
Moveme
nts
Common Eye Problems
Eye
Abnorm
Eye
Movements
Common Eye Problems
CVA
Abnorm
Eye
Movements
Aneurys
m
DM
Common Eye Problems
Amauros
is
Fugax
Retinal
vessel
disease
Pupillary
Abnormali
ties
Cataracts
Eye
Uveitis
CRAO
Abnorm
Eye
Movements
Common Eye Problems
Eye
CRAO
CRAO
Source of
Emboli
Common Eye Problems
Amauros
is
Fugax
Retinal
vessel
disease
Pupillary
Abnormali
ties
Cataracts
Eye
Uveitis
CRAO
Abnorm
Eye
Movements
Common Eye Problems
Retinal
vessel
disease
Eye
Diabetes
Mellitus
Retinal vessel
disease
Hypertension
Hypercholes
terolaemia
Diabetes
Mellitus
Retinal vessel
disease
Background
Retinopathy
Maculopat
hy
Diabetes
Mellitus
Proliferati
ve
Retinopat
hy
Pre-prolif
Retionopa
thy
Background
Retinopathy
Maculopat
hy
Diabetes
Mellitus
Proliferati
ve
Retinopat
hy
Pre-prolif
Retionopa
thy
Dot
Haemorrha
ges
NORMAL eyesight
Background
Retinopathy
-present in almost all who have had type 1
diabetes for 20 years
-present in nearly 80 percent of those with type
2 disease for 20 years
Microaneurysms
Hard
Exudates
Backgrou
nd
Retinopat
hy
Maculopat
hy
Diabetes
Mellitus
Proliferati
ve
Retinopat
hy
Pre-prolif
Retionopa
thy
Diabetes
Mellitus
Pre-prolif
Retinopat
hy
Cotton
Wool
Spots
NORMAL EYESIGHT
Pre-prolif
Retionopathy
Venous
Irregularity
Pre-prolif
Retionopathy
REFER!
50% of patients progress to
proliferative retinopathy within 1-2 years
Backgrou
nd
Retinopat
hy
Maculopat
hy
Diabetes
Mellitus
Proliferati
ve
Retinopat
hy
Pre-prolif
Retionopa
thy
Diabetes
Mellitus
Proliferati
ve
Retinopat
hy
NVD
Neovascularisa
tion
NVE
NORMAL
EYESIGHT,
but
threatened....
Proliferative
Retinopathy
Proliferative
Retinopathy
REFER!
Backgrou
nd
Retinopat
hy
Maculopat
hy
Diabetes
Mellitus
Proliferative
Retinopathy
Pre-prolif
Retinopathy
Maculopathy
Diabetes
Mellitus
Early
and
Diffuse
EYESIGHT
AFFECTED
Maculopathy
Severe
and
Ischaemi
c
REFER!
Maculopathy
Diabetes
Mellitus
Retinal vessel
disease
Hypertension
Hypercholes
terolaemia
Retinal vessel
disease
Hypertension
Grade I
Grade IV
Hypertension
Grade III
Grade II
Grade I
Grade IV
Hypertension
Grade III
Grade II
Grade I
Grade IV
Hypertension
Grade III
Grade II
Grade I
Hypertension
Grade IV
Cotton
Wool
Spots
Grade III
Grade II
Haemo
rrhages
Grade I
Grade IV
Hypertension
Grade III
Grade II
Silver
Wiring
Grade I
Grade IV
Hypertension
Grade III
Grade II
Grade I
Grade IV
Hypertension
Grade II
A-V
Nipping
Grade III
Grade I
Hypertension
Grade IV
Cotton
Wool
Spots
Grade III
Grade II
Haemo
rrhages
Grade I
Papilloedem
a
Grade IV
Hypertension
Grade III
Grade II
Diabetes
Mellitus
Retinal vessel
disease
Hypertension
Hypercholesterolaemia
Common Eye Problems
Amauros
is
Fugax
Retinal
vessel
disease
Pupillary
Abnormali
ties
Cataracts
Eye
Uveitis
CRAO
Abnorm
Eye
Movements
Common Eye Problems
Amauros
is
Fugax
Retinal
vessel
disease
Pupillary
Abnormali
ties
Cataracts
Eye
Uveitis
CRAO
Abnorm
Eye
Movements
Amaurosis
Fugax = painless,
transient (secs/
mins), partial or
complete
Neourol
ogic
Embolic
Amaurosis
Fugax
Vasospasti
c/
Haemodyn
amic
Ocular
Idiopathi
c
Optic
Neuritis
(MS)
Neurologic
Embolic
Migraine
Amaurosis
Fugax
Vasospasti
c/
Haemodyn
amic
Ocular
Idiopathi
c
Neourol
ogic
Embolic
Amaurosis
Fugax
Vasospasti
c/
Haemodyn
amic
Ocular
Idiopathi
c
TIA
(cardiac/
carotid/
other)
Neurologic
Embolic
Amaurosis
Fugax
Vasospastic/
Haemodynamic
Temp
Arteritis
Ocular
Idiopathic
Common Eye Problems
Amauros
is
Fugax
Retinal
vessel
disease
Pupillary
Abnormali
ties
Cataracts
Eye
Uveitis
CRAO
Abnorm
Eye
Movements
Common Eye Problems
Amauros
is
Fugax
Retinal
vessel
disease
Pupillary
Abnormali
ties
Cataracts
Eye
Uveitis
CRAO
Abnorm
Eye
Movements
Horner's
Syndrom
e
Pupillary
Defects
Adie’s Pupil
CVA/SO
L
Common Eye Problems
Amauros
is
Fugax
Retinal
vessel
disease
Pupillary
Abnormali
ties
Cataracts
Eye
Uveitis
CRAO
Abnorm
Eye
Movements