Transcript Document

Pharmanex
Product Training
CordyMax Cs-4:
Dietary Supplement
CordyMax Cs-4 is an all-natural supplement
that promotes vitality and stamina without
the use of stimulants. CordyMax Cs-4
promotes the efficient use of oxygen and
increases the body’s resistance to daily
environmental stresses.
Vitality and Stamina.
CordyMax Cs-4: What is it?
• CordyMax Cs-4 is an all natural supplement that
promotes vitality and stamina without the use of
stimulants.
• CordyMax Cs-4 is a proprietary natural fermented
product derived from fresh, natural Cordyceps
sinensis, a mushroom from Qinghai Province in
China.
• Cordyceps sinensis is a blade shaped mushroom
that grows primarily in the Tibetan plateau at
altitudes above 14,000 feet.
CordyMax Cs-4: Benefits
• Promotes vitality and stamina in all
essential body organs
• Reduces fatigue
• Promotes healthy lung function
• Improves liver and kidney functions
• Positive benefit for sexual health
• Support of 30 clinical studies
CordyMax Cs-4: Advantage
• Unique fermentation process
• Standardised
– HPLC to guarantee potency and consistent results by
supplying minimum levels of 0.14% adenosine
• Clinically and scientifically proven
– 15 years of research; over 30 clinical studies
– Contains no stimulants, reduce fatigue, increase energy
– Not dependent on anecdotal data for efficacy
• Studies support resistance to free radical attack
– Superoxide Dismutase
– Mitochondria
CordyMax Cs-4: Advantage
• Pharmanex’s exclusive CordyMax Cs-4 formula is
recognised in China as the fermented Cordyceps
mushroom product offering health benefits most
comparable to the rare and protected wild
mushroom of the Tibetan high plateau.
• CordyMax Cs-4 has been placed under intellectual
property protection, and only Pharmanex has an
exclusive license outside of China.
CordyMax Cs-4: Clinical Studies
Health Benefit
Respiratory
Sexual function
Cardiovascular function
Free radical scavenging
Kidney function
Immune function
Liver function
Anti-fatigue
No. of studies
20
5
4
4
3
2
1
2
Recent data:
Improved bioenergy status in animals (JACM 2001;7:231-240)
Elevated VO2max in frail elderly subjects (MSSE 1999;31:S174)
Enhanced exercise performance in athletes (MSSE 2001;33:S164)
CordyMax Cs-4: Clinical Studies
• Abstracts
• Supplementation with Cordyceps Cs-4
fermentation product promotes fat metabolism
during prolonged exercise.
• Increased aerobic capacity in healthy elderly
humans given a fermentation roduct of Cordyceps
Cs-4.
• CordyMax Cs-4 enhances endurance in sedentary
individuals.
CordyMax Cs-4: Clinical Studies
• Pharmanex Web Site http://www.pharmanex.com.au/au/au/produ
ct/clinical_studies_references.shtml
• PubMed Web Site http://www.ncbi.nlm.nih.gov/entrez/query.fc
gi
31P
NMR spectroscope (w/MDPA ref)
JACM 2001;7:231-240
•Male C57-BL/6 mice (n=5-6/group)
•Treatment by gavage for 7days
•Hepatic ATP levels and inorganic phosphate by 13P NMR
•B-ATP and B-ATP/Pi ratio increased in both Cs-4 groups (p<0.001)
•“Cs-4 increased hepatic energy state”
6
5
Hepatic B-ATP
B-ATP/Pi
*
*
4
3
2
1
0
Placebo
Cs-4 (200mg/kg/d)
Cs-4 (400mg/kg/d)
* = P<0.001
MSSE 1999;31:S174
•30 healthy, elderly Chinese subjects
•Randomized to Cs-4 (3g/d/6wk) or placebo
•Incremental work rate cycle ergo meter protocol
•Increased VO2max 1.88+0.13 to 2.00+0.14 (p<0.05)
“Cs-4 has potential for improving exercise capacity and
resistance to fatigue”
+9%
0%
CordyMax Cs-4 Placebo
MSSE 2001;33:S164
Percent change from baseline
•30 highly trained male endurance athletes
•Baseline VO2max = 62.6+7.7 ml/kg/min
•Cs-4 (4.5g/d/6wk) or placebo
•60 min sub maximal performance test at 70% VO2max
“Cs-4 has positive circulatory and metabolic effects and may enhance fat
mobilization and beta-oxidation during prolonged exercise”
15
NS
10
NS
5
0
-5
-10
P=0.058
NS
NS
HR
O2 Pulse
RER
LA
P=0.056
P<0.05
P<0.05
-15
Placebo
Cs-4
CordyMax Cs-4:
Enhances Endurance in Sedentary Individuals
Pharmanex data demonstrates that healthy sedentary adults consuming
CordyMax Cs-4 for 12 weeks can:
(1) Increase oxygen consumption (+5% in VO2peak)
(2) Enhance fat metabolism
(-2% in RER)
(3) Improve exercise performance (-20 sec in 1-mile walk)
(+3% work output on bike test)
This confirms previous findings in animals, frail elderly and elite athletes,
showing a metabolic effect of Cs-4 supplementation to favourably
influence oxygen consumption, energy metabolism and endurance
performance.
CordyMax Cs-4: Recommended
Adult Usage
• For persons with busy, stressful and/or hectic
lifestyles; athletes and the elderly, those desiring
increased stamina.
• Take 2 capsules 2 to 3 times daily with food and
drink.
• Women who are pregnant or are lactating, and
people with know medical conditions, should
consult a physician prior to taking supplements.
Keep out of reach of children.
CordyMax Cs-4: Q&A
• Who should take CordyMax Cs-4?
• As a food supplement for use by individuals with busy, hectic
lifestyles, athletes and the elderly, and those desiring increased vitality
without the use of stimulants.
• How are the ingredients in CordyMax Cs-4 standardised?
• Each 525 mg capsule of proprietary CordyMax Cs-4 is standardised by
HPLC to guarantee potency and consistent results by supplying
minimum levels of 0.14% adenosine. An additional test method is used
to standardise to less than 6% mannitol, which is an indicator of
polysaccharide content.
• If I’m taking CordyMax Cs-4, do I need to take OverDrive?
• CordyMax Cs-4 is a daily supplement for your daily stamina and
vitality. OverDrive is focused more for the athlete. Even if you are not
an athlete but have a busy and hectic lifestyle, CordyMax Cs-4 and
OverDrive taken together is a great combination.
CordyMax Cs-4: Marketing
Material
•
•
•
•
•
Pharmanex Brochure (5 pk)
Pharmanex Cap (ea)
Power of Wisdom & Knowledge Video (ea)
Pharmanex Pill Box (ea)
CordyMax Cs-4 Brochure (5 pk)
$8.00
$12.95
$7.50
$3.00
$4.50
CordyMax Cs-4: Summary
• Capsules
• Vitality and Stamina
– Increased VO2 max
– Healthy lung function & capacity
• Cordyceps sinensis proprietary ingredient
• Standardised
• Over 30 clinical studies