Transcript Lyme Disease

Lyme Disease
A New Name for
an Old Condition?
August 2008, Sonoma County
California
Cecile Jadin
South Africa
Continued Discontinuity In
Microbiology
 Examples: H.Pylori,Leishmaniosis,
Trypanosomiasis, Toxoplasmosis, Rickettsia…
 Slows down progress in research
 Masks the pandemia of today's germs already highlighted by Homer in the sixth
section of the Iliad:
“migration of gulls who every winter carry the
carnage and war from one end of the earth to the
other”
 Medicine is built mainly on new findings
 If this were the case for Mathematics and
Physics, how chaotic would it be?
Borreliosis’ Case
 Drury discovers Malgache fever in 1702 - Central
Africa
 Early 1900’s Spirochete hispanicum in Spain
 A few years later, Nicolle tracks Malgache fever Northern Africa
 Scheltz, while working in Congo in 1933, reports
the same recurrent fever associated with
spirochete
 In 1944, Palakov publishes that the relapsing fever
disabling patients in Cape Town is due to the same
bug
 Heisch claims the recognition of Borreliosis as
causing the never-ending fever in 1950 - Kenya
 Borrelia burgdoferi, isolated in 1982 by Willy
Burgdorfer after a mysterious outbreak of arthritis
in Connecticut in 1975, is Americanised as Lyme
disease
The Vector is Known
Ixodes Ricinus & Others
Life span of 4 Years
Walking distance of 50 meters/life time
Can lay 1000 eggs
Can be genetically infected - trans-ovarian
transmission of Rickettsia has been observed
 Is more virulent than ever:
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 Insecticides: tick & eating birds
 Global Warming
 Traffic intensity
 More than one organism is needed to collapse
the immune system
Check as many tick-born
A
tick contains
an
 Lyme
isas
a your
tick-born
diseases
labaverage
offers
ofdisease
80 germs of insect bites
in
presence
or close contact
Our Diagnostic Tools
 Medical history Contact?
Insect Bite?
 Symptomatology - Headaches?
Chills? Fatigue? Muscular & Joints Pains?
Carditis?…
 Medical examination - Rash?…
 Biological investigation
Biological Investigation
Infections
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
Rickettsia Prowazeki
R. Mooseri
R. Conori
Q Fever
Mycoplasma
Pneumoniae
Chlamydia Pneumoniae
Chlamydia Trachomatis
Chlamydia Psittaci
Brucellosis
Toxoplasmosis
H. Pylori
Bartonella
Lyme Disease:
Direct examination preferred
 Bilharzia
Dysfunction
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FBC
ESR
LFT
TFT & Thyroid antibodies
IgE
Iron Study
Kidney Study
Glucose
CRP
RF
ANF
Cardiolipin
Cholesterol
Biological Window
500 Patients Randomly Sampled
TFT
KFT
ESR
FBC (abs
Thyroid AB
Toxoplasmosis
Borreliosis
CRP, RF, ANF
Iron
Mycoplasma
LFT
Bartonella
Chlamydiae non spec
Lympho Study
Rickettsial Infection
0%
10%
20%
30%
40%
50%
60%
70%
80%
90%
100%
1 Germ  Different Diseases
1 Disease  Different Causes
 According to its
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position in the human 
One
disease
at a time
body,
spread
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throughout
the another
One
disease after
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ReticuloEndothelial
All diseases together
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tissue
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 According to its
specific toxicity
 Facing the
physiological
conditions of the host
 Symbiosis of germs
Neurological Disease
Psychiatric Disease
Rheumatologic Disease
Cardio-Vascular Disease
Dermatologic Disease
Etcetera
Experience with
Treatment
 Established by French school 30 years ago,
used in our clinic since 1992
 Antibiotics
 Preferably orally - except for Ceftriaxone
 Pulse Therapy as opposed to continuous
 High Dosage
 Associated - Bacteriostatics + Bactericidals
 Alternated
 With Adjuvants: vit B com - probiotics - gastric
proton inhibitor
 Vaccination - Mutation - Relapse