Transcript Document

Questions?
Establishing an Integrative
Care Center
Dr. Brent Bauer
Dr. Adam Perlman
Thursday, October 4th
Title by Presenter Name
From CAM to Integrative Medicine
at Mayo Clinic
Research Informing Practice and Improving Care
Brent A. Bauer MD
Director, Complementary and Integrative Medicine Program
Mayo Clinic
Department of Medicine
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Massage Therapy – Mayo Clinic
Pilot Trial
58 cardiac surgery patients
Massage
therapy
vs
quiet
relaxation
Decreased
Pain
Anxiety
Tension
Cutshall, Comp. Therap.Clin. Practice, 2009
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Massage Therapy after CV Surgery
Control group (n=28)
V
A
S
Massage group (n=30)
10
10
8
8
6
6
4
4
2
2
0
0
Before
After
Before
After
Anxiety Level
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Massage Therapy after CV Surgery
Control group (n=28)
V
A
S
Massage group (n=30)
10
10
8
8
6
6
4
4
2
2
0
0
Before
After
Before
After
Pain level
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Massage Therapy – Mayo Clinic
Randomized – Controlled Trial
 113 cardiac surgery patients
 MT therapy days 2,4 vs. quiet relaxation
 Decreased pain
P<0.001
 Decreased anxiety
P<0.001
 Decreased tension
P<0.001
 Increased relaxation
P<0.001
Bauer, Comp. Therap. Clin. Practice, 2010
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Massage Therapy at Mayo Clinic
Other Studies
 MT for colo-rectal surgery patients
2009
 MT prior to cardiac interventions
2009
 MT for thoracic surgery patients
2011
 MT for breast cancer surgery pts
2012
 MT for cardiologists and nurses
2010
 MT for cardiac ultrasonographers
2011
 MT for in-patient nurses
2012
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Massage Therapy at Mayo Clinic
The Impact
 Massage therapy now routine at MC
 Domino effect
 Small investment > “snowball” returns
 48 hospitals in US
 7 international hospitals
 Australia, Austria, China, Ireland, Switzerland, Turkey
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Massage Therapy at Mayo Clinic
The Vision
Massage therapy routinely available to all
Hospitalized
patients at
Mayo Clinic
Family
members
Staff
Continue to use the Mayo experience to transform
health care in the U.S. and around the world
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Questions
[email protected]
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Bibliography
 Effect of massage therapy for postsurgical mastectomy recipients. Drackley NL,
Degnim AC, Jakub JW, Cutshall SM, Thomley BS, Brodt JK, Vanderlei LK, Case JK,
Bungum LD, Cha SS, Bauer BA, Boughey JC. Clin J Oncol Nurs. 2012 Apr;16(2):121-4.
PMID:22459520
 Feasibility and effectiveness of massage therapy for symptom relief in cardiac
catheter laboratory staff: a pilot study. Keller SR, Engen DJ, Bauer BA, Holmes DR Jr,
Rihal CS, Lennon RJ, Loehrer LL, Wahner-Roedler DL. Complement Ther Clin Pract.
2012 Feb;18(1):4-9. Epub 2011 Sep 23. PMID:22196566
 Effect of massage on pain management for thoracic surgery patients. Dion L,
Rodgers N, Cutshall SM, Cordes ME, Bauer B, Cassivi SD, Cha S. Int J Ther Massage
Bodywork. 2011;4(2):2-6. Epub 2011 Jun 29. PMID:21847428
 Massage therapy after cardiac surgery. Wang AT, Sundt TM 3rd, Cutshall SM, Bauer
BA. Semin Thorac Cardiovasc Surg. 2010 Autumn;22(3):225-9. Review.
PMID:21167456
 The effect of chair massage on muscular discomfort in cardiac sonographers: a pilot
study. Engen DJ, Wahner-Roedler DL, Nadolny AM, Persinger CM, Oh JK, Spittell PC,
Loehrer LL, Cha SS, Bauer BA. BMC Complement Altern Med. 2010 Sep 16;10:50.
PMID:20846441
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Bibliography
 Effect of massage therapy on pain, anxiety, and tension in cardiac surgical patients: a
pilot study. Cutshall SM, Wentworth LJ, Engen D, Sundt TM, Kelly RF, Bauer BA.
Complement Ther Clin Pract. 2010 May;16(2):92-5. Epub 2009 Nov 14.
PMID:20347840
 Effect of massage therapy on pain, anxiety, and tension after cardiac surgery: a
randomized study. Bauer BA, Cutshall SM, Wentworth LJ, Engen D, Messner PK, Wood
CM, Brekke KM, Kelly RF, Sundt TM 3rd. Complement Ther Clin Pract. 2010
May;16(2):70-5. Epub 2009 Jul 14. PMID:20347836
 Massage therapy reduces tension, anxiety, and pain in patients awaiting invasive
cardiovascular procedures. Wentworth LJ, Briese LJ, Timimi FK, Sanvick CL, Bartel
DC, Cutshall SM, Tilbury RT, Lennon R, Bauer BA. Prog Cardiovasc Nurs. 2009
Dec;24(4):155-61. PMID:20002340
 Value of massage therapy for patients in a breast clinic. Pruthi S, Degnim AC, Bauer
BA, DePompolo RW, Nayar V. Clin J Oncol Nurs. 2009 Aug;13(4):422-5.
PMID:19648098
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Questions?
Title by Presenter Name
American Massage Therapy Association
October 4, 2012
Adam Perlman, MD, MPH
Executive Director
Duke Integrative Medicine
At the Beginning
New Jersey
• Siegler Center for
Integrative Medicine
• Services Offered
• Who do you hire
• Research
Pilot Study (2006)
• Randomized controlled trial; n=68
– Massage vs. wait list
• Intervention: Whole body, Swedish massage for 8 weeks
– Standard techniques of petrissage, effleurage, and tapotement
– 60 min twice weekly x 4 weeks
– 60 min once weekly x 4 weeks
• Outcomes: function (WOMAC), pain (VAS), ROM, 50-ft walk
• Results: well tolerated, decreased pain, and improved function
• Effects persisted for weeks after cessation of massage
1. Archives of Internal Med. 2006;166:2533-2538
UMDNJ
• Serving the underserved
• Institute for Therapeutic
Massage
• Research
Dose-finding study (2009-2011)
• 2-Year study to define the ‘optimal practical’ dose of massage
for OA of the knee
• Designed to inform a future, more definitive trial
• Randomized, wait list-controlled, clinical trial
• 5-arm trial
– 4 different ‘doses’ of standardized, whole body Swedish
– wait list control
• Supported by NCCAM grant R01 AT004623
• Trial Registration: clinicaltrials.gov NCT00970008
Dose-finding study - Design
• Four distinct ‘doses’
– 1. 30 min/week x 8 weeks (240 min total)
– 2. 30 min biweekly x 4 weeks, 30 min weekly x 4 weeks (360 min
total)
– 3. 60 min/week x 8 weeks (480 min total)
– 4. 60 min biweekly x 4 weeks, 60 min weekly x 4 weeks (720 min
total)
– 5. Usual Care (no massage)
• Included:
– Adults with radiographically confirmed OA of the knee
– Self-reported pain between 4-9 on VAS
• Excluded:
– RA, fibromyalgia, intraarticular injections, knee replacement
• Assessed: baseline, 8-, 16-, and 24-weeks
• Outcomes: WOMAC, VAS, ROM, 50-ft walk
Manualization
• Goal: to produce a study protocol that was tailored to subjects with
OA of the knee, while respectful of the individualized nature of
massage therapy
• How to standardize an inherently individualized intervention?
– CAM/nonphamacological research dilemma
• 2-month process
– Massage therapists from pilot study
– Investigative team
– Massage scientists
• Constraints
– Standard techniques
– Reproducibility
– Flexible for individual subject variability
Manualized protocols
Results
•Recruitment completed two months ahead of schedule
– Free massages…
– And more free massages!
•125 enrolled
– 119 completed 8-week assessments
– 115 completed entire trial
– Intervention delivered: 11/2009 – 10/2010
Conclusions
• Winner: 60-min once weekly
• ‘Optimal-practical’= best bang for the buck
– producing the greatest ratio of desired effect compared to costs
– costs = time, labor, and convenience
• Reinforced results of pilot study
• Dose used for current study -
Duke
• Shifting the model
o Access
• Forging relationship
o DCI
• Research
Current Study
• Phase 2b Efficacy Trial
– Using 60-min once weekly dose
– Massage vs. light touch vs. wait list
– 52-week follow-up
– N=219 at three sites: Duke, UMDNJ, Yale
– Cost-effectiveness
– Biomarkers
• ‘Unanticipated Benefits’
– Modeled on studies by Cherkin et al. (Seattle)
– Qualitative study
– Participants of dose-finding study
– ‘What else?’
The good, the bad, and the ugly.