Transcript Slide 1

Preparing Your Lab
for an IACUC or
AAALAC Inspection
Office of the Campus
Veterinarian
The following slides are to serve as a
reminder of areas that all animal users
are expected to know and be able to
appropriately respond, if asked during an
AAALAC or IACUC site visit.
If you need assistance with any of these
areas, please contact the Office of the
Campus Veterinarian.
First Impressions
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Keep laboratory neat and organized
 This says a great deal about the lab
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Convey image that animal
users are interested in a
quality program
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Good Animal Care = Good Science
Or is this your lab?
Animal Care Acronyms to Know
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AAALAC-International - Association for the Assessment and
Accreditation of Laboratory Animal Care-International
• IACUC - Institutional Animal Care and Use Committee
• ASAF - Animal Subjects Approval Form
• USDA - United States Department of Agriculture
• AWA – Animal Welfare Act
• AALAS – American Association of Laboratory Animal Science
• OLAW – Office for Laboratory Animal Welfare
Role of the IACUC
• Protocol review
• Program review
• Facilities review
• Address animal concerns
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Note: The IACUC is required to conduct the same
level of review twice per year as the AAALAC site
team conducts once every three years.
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Have you attended a recent Animal Awareness
Seminar? Maybe you should.
Animal Concerns
What can you do?
Animal Subjects Approval Form
• Know your animal protocol (ASAF).
• It better match your grant application.
• Refer to the protocol often.
• Make no deviations from the protocol.
• There is no such thing as a pilot study that
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does not need IACUC approval.
Has everyone in your lab read it and know
where it is located?
Sick animal?
• What do you do? Post your procedure.
• What do you do with a sick animal on weekends?
• Do you know the point at which the animal should be
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euthanized?
Remember: ALL clinical care of animals MUST be
coordinated through the Office of the Campus
Veterinarian.
Anesthesia/Analgesics
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Use anesthetics only as described in ASAF
Gas anesthetics vaporizers should be
calibrated frequently
Use a chemical fume hood or other means to
scavenge gas anesthetic agents
appropriately
Rodent Aseptic Surgery
• Must follow WSU published
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“Guidelines”
Appropriate sterilization of
instruments
Surgical preparation of
 Animal
 Surgeon
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Monitor anesthesia
 An anesthetized animal cannot be left
unattended
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Post-Operative Care consistent
with
 WSU “Guidelines”
 And described in your ASAF
Clinical Records for warm-blooded species other
than rodents
 Each animal must have an individual clinical record.
 Clinical records must be available to the OCV staff at
all times.
 Clinical records must be kept
with the animal.
 All procedures conducted
on the animal must be entered
into its clinical record.
Drugs
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Only use those drugs listed in the ASAF
Other drugs that may be needed for
clinical care must be under the direction
of a veterinarian.
Do you have a system for identifying and
disposing of expired drugs?
Controlled substances will be audited.
Know the DEA rules!!
Euthanasia
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Your euthanasia procedure must be as
written in your ASAF.
What methods do you use to assure death?
Physical methods of euthanasia require
specialized training and justification.
Use of a guillotine for euthanasia requires
that it be properly maintained.
Occupational Health and Safety
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All animal users MUST be registered in the
Animal Contact program. Are you?
Physical injury issues:
 Do not recap needles – get our EH&S
policy.
 Bite wounds – do you know what to
do?
 Personal Protective Equipment – do
know what is required?
Chemicals
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All chemical containers must be labeled.
If appropriate, an expiration date must be
on the label.
Keep chemicals away from human or
animal food items.
Certifications
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Gas anesthetic vaporizers must be certified annually.
Hoods must be certified annually.
Training with Animals
• Training for Research staff
 General animal use training is
provided at least monthly
 Rodent training is provided as
needed/required by the faculty
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Training for Animal Care staff
 Documented on-the-job
 Certification is ideal (AALAS)
Animal Housing
• To remain consistent with the Guide, NO overcrowding is permitted
 Review “Overcrowding” policy – rodent housing most commonly affected
 Delayed or incomplete weaning is most common cause of overcrowding
conditions
• Identification
 Cage cards must be visible
 Animals must be identified
• No housing of animals outside the vivariums unless approved by the
IACUC
 Warm blooded animals except laboratory reared rats, mice and birds cannot be
outside the vivarium for longer than 12 hours (USDA regulations).
 Rats, mice, and birds and other vertebrates not covered by the USDA regulations
can be kept outside the central animal facilities for up to 24 hours. (PHS Policy)
What do you do if you must clean the
cages or cage accessories yourself?
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You must have a method to ensure an
adequate level of sanitation.
 This can be accomplished by
periodically (at least monthly)
culturing the cage or cage
accessory.
• Contact the OCV for assistance.
WSU Animal Policies
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Designed to help users and WSU to maintain a
program consistent with the “Guide”.
Designed to reduce costs when possible.
Designed to treat all investigators equitably.
Are Posted on OCV web site - Please review often.
If you need clarification or assistance, contact the
OCV at 335-6246.
Useful Web sites
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http://campusvet.wsu.edu - Office of the Campus
Veterinarian
http://hazel.forest.net/latanet/client/wsu/introducti
on.htm - WSU’s On-line Training Program
http://www.aalas.org – Animal Technician
certification program
http://www.aaalac.org – AAALAC International
home page
Please contact us if you
have any questions.
Office of the Campus
Veterinarian
335-6246
campusvet.wsu.edu