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How to promote entrepreneurship and
commercialization of research
at an old General University?
Lars Jonsson
Head of UU Innovation & UUAB Holding Company
Uppsala University
Sweden
Old General Universities
• Difficult to grasp
• Even more difficult to manage
• Long processes to achieve living policies
• Strong academic culture
– It is not noble to commercialize
– Professor's privilege
Uppsala University
• 530 years in business…
– Strong academic traditions
– Academic research should stand free!
• Heavily decentralized
• Strongly divested
– Theology  Space Technology
Nine faculties,
Three disciplinary domains
~450 M€ AnnualArts
turn over
Educational Sciences
Arts
&
Social Sciences
Education
32%
Languages
Law
Social Sciences
Research
Theology 68%
Medicine
Pharmacy
Science and Technology
Professor's privilege
A Swedish specialty…
• All results are the researchers private equity
– The University has no rights
– Only Sweden; (Italy with some restrictions)
• Can not use University Money for
– Patent applications
– Investments in shares
– Investments in developing projects
Tough odds for patents!
Canadian survey
» Thomas Asterbot, Univ of
Toronto, 2003
1061 out of 1091 failed….
< 7 % reached the market
0,5 % became profitable
Research is an investment
Return of investment:
–
–
–
–
Competitive work force
Competitive inventions
Knowledge based economy
Increased welfare
A University Innovation System is
mandatory to achieve this !
Commercialize research
We have a mission to make our
research useful to society
through commercialization and
patents.
Anders Hallberg,
Vice-Chancellor,
Uppsala University, 2006
Patents are instruments
• Patents and Knowledge Transfer
should not be the goal for a university
institution
• They are tools to establish a relation
and enforce the institution!
”The Svedberg Group”
- the cradle of modern biotechnology industry!
• The Svedberg
– Nobel Laureate 1926
– The Ultracentrifuge
• Arne Tiselius
– Nobel Laureate 1949
– Electrophoresis and Chromatography
– Gel filtration, phase partition etc
Today:
GE Health Biosciences
Uppsala Bio
Invention to company turn-over
Commercialization
Fragmin™
Biacore
67 MUSD
Q-Med
Pharmacia Biotech
  GE Healthcare
600 MUSD *
Xalatan™
1.300 MUSD
78 MUSD
Turn-over today
Biotage
Olink
114 MUSD ~2,600 MUSD / year
AMO Uppsala
Phadia
204 MUSD
of which > 1,000 MUSD is
based in Uppsala
1940
Electrophoresis
Dextran
1960
Function of
Hyaluronic
acid
1980
IgE
2000
Padlock Probes
Heparin
SPR Biosensors
Research
inventions
Microwave
syntheses
neuropeptides effect
on ocular blood flow
What have been done
- Organizational structure
UUAB
Holding
Company
STUNS –
Non-profit
university & society
foundation
Science Park
Technical
Bridge
Foundations
Ad hoc
Collaboaration
And spin-outs
1985
Liasion
office
1990
1995
2000
2005
• Owned by the University
• Arm length distance – no part of the Authority
• Legal form = private company
• The Government decides the object in
the Articles of Associations
What have been done
- Organizational structure
UUAB
Holding
Company
STUNS –
Non-profit
university & society
foundation
Science Park
University
Liasion
Company
CEF
Technical
Bridge
Foundations
Entrepreneurial
Educational
Programs
Innoventus
Life Science
Venture
Liasion
office
1990
ÅMA
A Wall
Chair
SHB
Patent
Grants
Foundation
Drivhuset
Student
Foundation
1985
Key Actors
Program
UIC
Business
Incubator
Patent
Office
Ad hoc
Collaboaration
And spin-outs
UU Innovation
1995
2000
Connect
PUB
meetings
Venture
Cup
2005
Material
Academy
What have been done
- Processes
• Recruiting right people
• Two-cultural
• Identify champions and relate
• Researchers
• External network of entrepreneurs
• Traditional spin-out strategy
• Start-ups, out licensing
• Collaborative research
• Pro active approach
Three main processes
Stimulate entrepreneurship
– Mainly students
– Business idea in a known market
Commercialization of inventions
– Research results, new products & markets
Creation of business opportunities
– Collaborative research platforms
– between disciplines and with companies
Stimulate 1
CEF -Centre for Entrepreneurship
University centre to stimulate entrepreneurship
– The School of Entrepreneurship
• Last year program for science students
• Real industrial project + theory & seminaries
– Project Management for students
– Seminaries for PhD students and researchers
– Seminaries for small knowledge based companies
Stimulate 2
Drivhuset
Student non-profit organization
– Inspire and stimulate students
– Support entrepreneurship vs employed
– Seminaries, lectures and hands on
– 50 student based companies per year
Stimulate 3
Anders Wall's chair
Professor chair in entrepreneurship
– Donation by Anders Wall, famous
local entrepreneur
– Education and research
– Entrepreneurial Day
• Entrepreneurs Academy
• Niklas Zennström, founder of Skype
– Dollar billionair, Uppsala alumni
Commercialization of research results
Disclosure process
Fuel
Find
Foster
Forward
Professional Project Management
Secure
Verify
Top Class
International
Research
Develope
Free Patent
Supervisor
Projects (UUAB)
New Company
Innoventus
UIC- Business
Incubator
Existing
Company
Existing
Company
Start-Ups
~ 150 discl/year
$
UUAB
UUAB
UUAB
$
$
$
$
VC $$$
Business Incubator
UIC
• We are business developers, not landlords
• Business coach 1 day / week
– Not for free, but pay when (if) you can
• UIC not an owner!
• Gives 7,9 times return on the tax investment!
UUAB
the Holding Company
UUAB value of portfolio
(last price value, adjusted for new investments)
70,00
• > 500 disclosures
60,00
• > 50 start-ups
50,00
40,00
• Invested ~ 8 M€
30,00
20,00
• High value creation
10,00
0,00
2000
2001
2002
2003
2004
2005
2006
2007
UUAB Results
(june 2007)
UUAB Invested
Realized profit UUAB (exits)
Value of portfolio
Running costs
Net profit
Consequently investments
Generated University Incomes
7,8 M€
6,7 M€
~ 7,7 M€
3,3 M€
~ 3,3 M€
~ 128 M€
~ 26 M€
Huge leverage for the University and the Society
A new entity
UU Innovation
Uppsala University
Commercialization
units
UU Innovation
UUAB
(Holding Company)
Forskarpatent
(Patent Office)
Uppsala
Innovation Centre
business incubator
• Strategy
• Partnership
• IPR management
• Business Law
• Entrepreneurship
• Innovation
Vice-Chancellor
(President)
Vice President
Vice President
Vice President
Faculty & Departments
Faculty & Departments
Faculty & Departments
Faculty & Departments
Faculty & Departments
Faculty & Departments
Faculty & Departments
Faculty & Departments
Society - the winner
Not always profitable
for the professor
for the university
for the Holding Company
Very profitable for the society
Gives valuable collaborations
Increases the competitiveness of the
university
Never ever give up
“Success is going from
failure to failure without
a loss of enthusiasm”Winston Churchill