POWERPOINT ® LECTURE SLIDE PRESENTATION by ZARA OAKES, MS

, The University of Texas at Austin

UNIT 1

3 PART A

Compartmentation: Cells and Tissues

HUMAN PHYSIOLOGY

AN INTEGRATED APPROACH

FOURTH EDITION

DEE UNGLAUB SILVERTHORN

Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

About this Chapter       Lumen and fluid compartments Biological membranes Intracellular compartments Tissue types and characteristics Tissue remodeling Organs Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

Three Major Body Cavities Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

Figure 3-1

Lumens of Hollow Organs  Hollow organs  Heart  Lungs  Blood vessels  Intestines  Lumen  Fluid-filled interior  Not the internal environment Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

Functional Compartments  Extracellular fluid  Plasma  Interstitial fluid  Intracellular fluid Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

Body Fluid Compartments Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

Figure 3-2

Cell Membrane: Overview Membranes in the body Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

Figure 3-3

Cell Membrane: Function      Physical barrier Gateway for exchange Communication Cell structure Phospholipid bilayer Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

Cell Membrane: Structure The fluid mosaic model of a biological membrane Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

Figure 3-4

Cell Membrane: Composition  Lipids  Micelles  Liposomes  Sphingolipids  Proteins  Integral  Peripheral  Lipid-anchored Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

Cell Membrane: Formation Membrane phospholipids form bilayers, micelles, or liposomes Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

Figure 3-5a

Cell Membrane: Formation Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

Figure 3-5b

Cell Membrane: Proteins The three types of membrane proteins: integral, peripheral, and lipid-anchored Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

Figure 3-6

Cell Membrane Map of cell membrane components Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

Figure 3-9

Cell Compartments  Cytoplasm  Cytosol  Inclusions  Organelles  Nucleus Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

Cell Compartments A map for the study of cell structure Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

Figure 3-11

Inclusions: No Membranes    Ribosomes  Free  Fixed Proteasomes Vaults Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

Cytoplasmic Proteins Fibers    Actin (microfilaments) Intermediate Microtubules  Tubulin  Centrioles  Cilia  Flagella Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

Centrioles, Cilia, and Flagella  Centrioles  Pull chromosomes  Form core in cilia  Cilia and flagella  Fluid movement Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

Centrioles, Cilia, and Flagella Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

Figure 3-13a –b

Cilia and Flagella     Motor proteins Microtubules  Nine pairs surrounding a central pair Cilia move fluids Flagella move sperm cell Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

Cilia and Flagella Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

Figure 3-13c –d

Cytoskeleton: Function      Cell shape Internal organization Intracellular transport Assembly of cells into tissues Movement Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

Cytoskeleton and Cytoplasmic Protein Fibers Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

Figure 3-14a

Cytoskeleton and Cytoplasmic Protein Fibers Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

Figure 3-14b

Mitochondria: Membrane-Bound   Membranes for protected reactions Mitochondria  Generates cell energy (ATP)  Have own DNA Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

Mitochondria: Membrane-Bound Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

Figure 3-16a

Mitochondria: Membrane-Bound Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

Figure 3-16b

Endoplasmic Reticulum (ER)  Smooth ER  Lipid synthesis  Conversion  Rough ER  Ribosomes  Protein assembly  Transport vesicles Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

Endoplasmic Reticulum Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

Figure 3-17 (1 of 3)

Endoplasmic Reticulum Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

Figure 3-17 (2 of 3)

Endoplasmic Reticulum Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

Figure 3-17 (3 of 3)