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NYC Syndromic Surveillance IFH HIT Meaningful Use Workshop 10/1/2010 Marlena Plagianos, MS NYCDOHMH [email protected] What is Biosurveillance? • “Collection and integration of timely healthrelated information for public health action achieved through the early detection, characterization, and situation awareness of exposures and acute human health events of public health significance.” Aaron T Fleischauer, PhD; Pamela S Diaz, MD; Daniel M Sosin MD . Biosurveillance: A Definition, Scope and Description of Current Capability for a National Strategy. Advances in Disease Surveillance 2008;5:175 2 Traditional Surveillance • Case definitions • Historically low compliance • Laboratory confirmation can be slow • Still important (e.g. H1N1 in NYC) 3 Laboratory Confirmation •Making firm diagnosis commonly relies on lab result •Limited in-house testing in outpatient setting (minutes) •Commercial laboratory testing takes time (daysweeks) 4 Traditional Reporting is Labor Intensive 5 Traditional Reporting is Labor Intensive 6 Syndromic Surveillance • Pre-diagnostic indicators of disease • Readiness scenarios: bioterrorism, pandemics • Objectives: – Timely, sensitive, specific surveillance – Detect outbreak before ‘astute clinician’ • Typical Process Collect data Process & code data Establish baseline Identify outbreak Sound alarm 7 New and Exciting Data Types Data source Level of data Data type Setting Care phase Medication sales School absences Nurse hotline call Aggregate Aggregate Individual Drug category Frequency Call type Pre-clinical Pre-clinical Pre-clinical Pre-diagnostic Pre-diagnostic Pre-diagnostic Chief complaint / Reason for Visit Individual Text, brief Clinical Pre-diagnostic EMS call Temperature Radiology Report Chest X-ray Diagnosis code Progress Note Individual Individual Individual Individual Individual Individual Run type Vital sign Text, narrative CPT code ICD9 code Text, narrative Clinical Clinical Clinical Clinical Clinical Clinical Pre-diagnostic Pre-diagnostic Pre-diagnostic Pre-diagnostic Diagnostic Diagnosis 8 EHR Syndromic Surveillance • The Primary Care Information Project (PCIP) uses different EHR data sources to conduct & pilot its syndromic surveillance activities • Some syndromes tracked using EHR data are: – Influenza-like Illness (ILI) – Fever – Gastrointestinal Illness (GI) • Case definitions for these syndromes based upon text in these structured fields: – Chief Complaint – Measured Temperature – Diagnosis (ICD-9 CM Code) 9 System Screenshot 10 Aggregate Level Syndromic Data • Only “Count” Data is collected 11 Data processing and syndrome coding Respiratory conditions Misspelling Shortness of breath Difficulty breathing Upper respiratory infection %Macro Resp; *Respiratory; IF CC=:'COUGH' OR CC=:'COUGHING' OR CC=:'SOB' OR CC=:'DIFFICULTY BREATHING' OR CC='BREATHING PROBLEMS' OR CC=:'SHORTNESS OF BREA' OR CC=:'DIFF BREA' CC='URI' OR THEN RESP=1; ELSE DO; RESP= INDEX(CC,"COUG") + INDEX(CC,"COUH") + INDEX(CC,"S.O.B") + INDEX(CC,"SOB") + INDEX(CC,"S O B") + INDEX(CC,"S O B") + INDEX(CC,"S.OB"); INDEX(CC,"BREAT") + INDEX(CC,"BEATH") + INDEX(CC,"DIB") + INDEX(CC,"D I B") + INDEX(CC,"D.I.B") + INDEX(CC,"BRATHING") + INDEX(CC,"DIFF BR") + INDEX(CC,"DIFF, BR") + INDEX(CC,"URI ") + INDEX(CC,"URI/") + INDEX(CC,"URI;") + INDEX(CC,"U R I") + INDEX(CC,"URI,") + INDEX(CC,"U.R.I") + 12 Analysis: Calculate Baseline Expected disease level • Approaches: Moving average, regression, time series methods. • Length of baseline: Years, months, days Adjustments • Long: Seasonal, secular, environmental (e.g. heat, pollen) • Short: Day of week, weekend/weekday, holidays, reporting failures 13 Analysis: Test Observed vs. Expected Significance tests Predetermined number of standard deviations Crossing statistical thresholds Signal 14 Analysis: Test Observed vs. Expected 15 Electronic Health Record Syndromic Surveillance During 2009 Pandemic H1N1 in NYC Friday 18 Saturday 19 Sunday 20 Monday 21 Tuesday 22 Wednesday 23 Thursday 24 Friday 25 Saturday 26 Sunday 27 Monday – Memorial Day 28 Tuesday 29 H1N1 in New York City: Where did patients seek treatment? Emergency Departments or Primary Care Clinics? Objective • To determine whether the timing of the increase in patient visits was different at emergency departments from primary care clinics during the spring 2009 H1N1 influenza outbreak across the 5 boroughs of NYC 31 Study Sites l 58 Primary Care Providers (PCP): – 9 Institute for Family Health (IFH) clinics – 49 practices enrolled in the NYCDOHMH PCIP (30 visits/day) v 50 Emergency Departments – 247 visits/day 32 Methods • Influenza-like Illness (ILI) as a broad estimate of H1N1 PCP ED • Fever + respiratory related reason for visit or diagnosis • Chief complaint of fever + a sore throat or cough, or a chief complaint of flu 33 Methods Compared number of days to a significant increase at EDs to PCP clinics using a logrank test • City-wide • By borough to see if there was a geographic difference Two Waves: • 4/24-5/8 • 5/14-6/4 34 ED, IFH and PCIP ILI Visits 35 ED, IFH and PCIP ILI Visits ED, IFH and PCIP ILI Visits Facilities with a significant increase in ILI volume 38 Results, April 24-May 8 Median Days to Facilities with Increase in Increase in ILI ILI ED 1-sided log rank Borough All 4 PCP ED PCP p-value 12 43/50 (86%) 36/58 (62%) <0.0001 Bronx 5 12 8/9 (88%) Brooklyn 3 14 12/15 (80%) 6/9 (67%) Manhattan 4 13 13/15 (87%) 11/19 (58%) 0.008 Queens 3 7 8/8 (100%) 6/7 (86%) Staten Island 14 10 2/3 (67%) 3/3 (100%) 0.902 10/17 (59%) 0.045 0.025 0.007 39 Results, May 14-June 4 Median Days to Facilities with Increase in Increase in ILI ILI ED PCP 1-sided log rank Borough All 4 8 ED PCP p-value 47/50 (94%) 50/58 (86%) <0.0001 Bronx 1 6 9/9 (100%) Brooklyn 4 12 13/15 (87%) 7/9 (78%) Manhattan 4 7 14/15 (93%) 17/19 (89%) 0.016 Queens 4 8 8/8 (100%) 5/7 ( 71%) Staten Island 5 8 3/3 (100%) 3/3 (100%) 0.012 16/17 (82%) 0.004 0.039 0.091 40 Findings • Emergency Departments experienced an increase in patients with ILI before Primary Care Providers • PCPs were vastly under-utilized during the outbreak • NYCDOHMH changed messaging to encourage visiting PCPs instead of EDs for mild illness 41 Future of Syndromic Surveillance Meaningful Use • Capability to submit syndromic data to health departments Regional Health Information Organizations (RHIOS), Hubs Data Validation and Quality Assurance 42 Online Resources CDC Flu Surveillance http://www.cdc.gov/flu/weekly/fluactivity.htm Distribute http://www.isdsdistribute.org/ 43