Transcript ATOLL trial
Enoxaparin versus unfractionated Heparin – ATOLL trial
Objective:
Study:
Population:
Endpoint:
to compare unfractionated heparin with enoxaparin in primary PCI
multi-center randomised open-label trial
patients with ST-elevation MI
30 day incidence of death, re-infarction, procedure failure or major
bleeding
Enoxaparin versus unfractionated Heparin – ATOLL trial
Enoxaparin versus unfractionated Heparin – ATOLL trial
Enoxaparin versus unfractionated Heparin – ATOLL trial
Conclusion
the effectiveness of enoxaparin compared to heparin was not different but
enoxaparin was associated with reduced MACE
Montalescot Lancet 2011;378:693-703