Transcript Voiding Dysfunction in Children
VOIDING DYSFUNCTION IN CHILDREN
Natalie Barganski, RN, CPNP
Objectives
The learner will be familiar with the presentation of voiding dysfunction The learner will be familiar with the evaluation of voiding dysfunction The learner will be familiar with different treatment options for voiding dysfunction
Physiology of micturition
Muscles of the bladder and the internal urinary sphincter are innervated by autonomic nerves, sympathetic and parasympathetic These nerves are integrated at various sites in the spinal cord, brain stem, midbrain, and higher cortical centers
Physiology of micturition
Two major functional roles of the bladder, storage and elimination of urine Filling Phase Storage Voiding Phase
Micturition continued
It evolves from involuntary bladder emptying during infancy to daytime urinary continence, usually around 4 years of age, then night time incontinence usually by 5 -7 years of age It is usually achieved after successful nighttime daytime bowel continence
Voiding Dysfunction
General term to describe abnormalities in either the filling and/or emptying of the bladder It constitutes ~ 40% of the Pediatric Urology Clinic
International Children’s Continence Society Global multidisciplinary organization of clinicians involved in the care of children with lower urinary tract dysfunction Standardized definitions for voiding dysfunction symptoms and disorders These definitions mostly apply to children who are five or more years of age
ICCS Definitions
Daytime frequency Incontinence Urgency Hesitancy Straining
ICCS Definitions continued
Weak stream Intermittent stream Holding maneuvers Post-micturition dribbling Residual urine
Categories
Nocturnal enuresis or nighttime incontinence Continuous or intermittent daytime urinary incontinence – these disorders are generally applied to children at least 5 years of age or older
Nocturnal enuresis
Monosymptomatic enuresis (MNE) Nonmonosymptomatic enuresis (NMNE)– occurs in children with enuresis who also describe other LUT symptoms Primary or secondary enuresis- 85% of all cases of childhood enuresis in primary
Nocturnal enuresis cont.
Both MNE and NMNE are often hereditary Three major causes: Nocturnal polyuria No family history 15%
INCIDENCE
One enuretic patient 44% Detrusor overactivity Two enuretic parent 77% Increased arousal thresholds Nevéus, T, et. al. ICCS MNE Standardization 2008
Daytime Urinary Incontinence
Due to underlying abnormalities of bladder function Overactive bladder Voiding postponement and underactive bladder Dysfunctional voiding Other conditions- giggle incontinence, vaginal voiding, primary bladder neck dysfunction
Etiology
Neurogenic causes Anatomic causes Functional causes
Prevalence
Nocturnal enuresis- 15% - 20% of 5 year olds, decreases with increasing age Daytime urinary incontinence Four – six year olds – up to 20% have daytime urinary incontinence Decreases with age Five – Six year old children – 10 % Six – Twelve year old children- 5 % Twelve – Eighteen year old children- 4 %
Categories based on risk
Minor Daytime frequency Giggle incontinence Stress incontinence Post void-dribbling Nocturnal enuresis Moderate Underactive bladder Overactive bladder Dysfunctional elimination syndrome Severe Hinman Ochoa Myogenic failure
Associated conditions
Urinary tract infection Vesicoureteral reflux Constipation and dysfunctional elimination syndrome Behavioral and neurodevelopmental issues Bladder extrophy, epispadias, ectopic ureter, neurogenic bladder
Assessment of urinary incontinence
Main goals: Find those that are at risk for upper tract deterioration in order to prevent of renal impairment Establish the cause of incontinence Improve quality of life
History & Physical
History is the KEY in determining the type of disorder Birth history Child’s medical history Family medical history Developmental history
Voiding History
Toilet training history Voiding schedule Symptoms of voiding dysfunction Diet intake, including fluid intake (caffeinated) Bowel habits Family conflict or stress, behavior, peer relations Sleep Treatment strategies
Clinical Tools- Voiding Questionnaire
Tools- Bladder (Voiding) Diary
Tools- Bristol Stool Chart
Physical Examination
Focus is on detecting neurologic and urologic abnormalities Height/weight Blood pressure Abdominal palpation Lower back Neurologic exam Genital examination
Investigations
UA, culture Nocturnal urine production Bladder scan Uroflow with or w/o EMG RUS VCUG MRI Urodynamic studies Dynamic renal imaging
Management
FIRST- Treatment of Constipation 40% of children with LUT symptoms have constipation Large retrospective study of 234 patients showed a resolution of constipation was associated with elimination of wetting in 89% and 63 % of children with daytime or nighttime urinary incontinence, and prevention of UTIs Loening-Baucke, V. Pediatrics 1997; 100-228
Management
When to start treatment? When the child is ready!
Nonpharmacolgic or conservative treatment- Voiding Behavior Modification A partial response with > 50% reduction of incontinent episodes Allen, et al. Urology 2007; 69:962 Weiner, et al. J Urol 2000; 164-786
Management
If conservative treatment fails to relieve symptoms treatment is condition specific NE- desmopressin, alarm, maybe anticholinergics, imipramine OAB- anticholinergic medication can be beneficial
Management
Underactive bladder- timed voiding is important, avoid anticholinergics, alpha adrenergic blockade has been helpful in relaxing bladder outlet Non-neurogenic dysfunctional voiding- concern for upper urinary tract deterioration, may need urodynamics, pelvic floor relaxation techniques, biofeedback, or an alpha antagonist
Dysfunctional voiding
Compensatory detrusor hypertrophy and hyperplasia Small capacity trabeculated bladder that may elevate bladder pressures Vesicoureteral reflux and resultant upper tract renal damage Detrusor decompensation and hypocontractility May need CIC or surgery
Management
Biofeedback- therapy teaches children how to identify and control the muscle groups involved in voiding Reserved for children with detrusor sphincter dyssynergia contributing to daytime incontinence despite behavior modifications/pharmacotherapy Helpful in children with significant post void residuals who have recurrent UTI and constipation
THANK YOU!! QUESTIONS?