Transcript Klug9chapt17

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Concepts of Genetics
Ninth Edition
Klug, Cummings, Spencer, Palladino
Chapter 17
Regulation of Gene Expression in
Prokaryotes
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17.1 Prokaryotes Regulate Gene
Expressions in Response to
Environmental Conditions
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17.2 Lactose Metabolism in E. coli Is
Regulated by an Inducible System
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Figure 17.1
17.2 Lactose Metabolism in E. coli Is
Regulated by an Inducible System
17.2.1 Structural Genes
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Figure 17.2
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Figure 17.3
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Figure 17.4
17.2 Lactose Metabolism in E. coli Is
Regulated by an Inducible System
17.2.2 The Discovery of Regulatory Mutations
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17.2 Lactose Metabolism in E. coli Is
Regulated by an Inducible System
17.2.3 The Operon Model: Negative Control
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Figure 17.5
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Figure 17.5a
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Figure 17.5b
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Figure 17.5c
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Figure 17.6a
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Figure 17.6b
17.2 Lactose Metabolism in E. coli Is
Regulated by an Inducible System
17.2.4 Genetic Proof of the Operon Model
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constitutive
trans element
cis element
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Table 17.1
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Figure 17.7
17.3 The Catabolite-Activating Protein
(CAP) Exerts Positive Control over the
lac Operon
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Figure 17.8
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Figure 17.8a
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Figure 17.8b
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Figure 17.9
17.4 Crystal Structure Analysis of
Repressor Complexes Has Confirmed
the Operon Model
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Figure 17.10
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Figure 17.11c
17.5 The Tryptophan (trp) Operon in E. coli
Is a Repressible Gene System
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Figure 17.12
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Figure 17.12a
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Figure 17.12b
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Figure 17.12c
17.6 Attenuation Is a Critical Process during
the Regulation of the trp Operon in E.
coli
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Figure 17.13
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Figure 17.13ab
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Figure 17.13c
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Figure 17.13d
17.7 TRAP and AT Proteins Govern
Attenuation in B. subtilis
TRAP = trp RNA-binding attenuation protein
AT = anti-TRAP
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Figure 17.14
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Figure 17.14a
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Figure 17.14b
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17.8 The ara Operon Is Controlled by a
Regulator Protein That Exerts Both
Positive and Negative Control
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Figure 17.15
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Figure 17.15a
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Figure 17.15b
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Figure 17.15c