Transcript Generic PrimeStore Presentation

Presentation on
Longhorn Vaccine & Diagnostics LLC
PrimeStore® Suite of Products and Pipeline
1747 Citadel Plaza, Suite 206, San Antonio, Texas 78209
2 Bethesda Metro Center• Suite 905 • Bethesda, MD 20814
Phone: (210) 826-0910
Email: [email protected]
www.lhnvd.com
Issues with Specimen Collection
collection
Transport
< 4 Days: 4˚C packs
Laboratory testing
Transport Medium: REMEL, Copan, BD
or raw clinical specimen
• Sample pre-treatment
> 4 Days: Dry Ice
• Requires cold chain (4˚C packs or -70˚C dry ice) - $$$
• Samples are viable and potentially infectious
• Shipment restrictions---hazardous materials and packaging,
special handling - $$$
• Quality control, i.e., temperature, transport monitoring
documentation
• Stabilization/preservation of DNA/RNA from sample,
short transport window
PrimeStore® Molecular Transport Media
• Target: “From Sputum to Sequencing”
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No BSL3?
No power?
No cold chain?
No timely specimen transportation?
• No Problem!
• PrimeStore® MTM, the Safe, Reliable, Accurate, Affordable
Collection-to-Detection System
– “The Front-End for all Molecular Diagnostics”
PrimeStore MTM™
Advantages:
• Collect and transport at ambient temperature
• Ready for storage (in collection tube)
• Kills microbes, destroys nucleases (DNase/RNase)
and stabilizes and preserves DNA/RNA
– Enhances nucleic acid testing sensitivity
• Compatible with silica-based extraction
methodologies including spin columns and beadbased extraction kits
PrimeStore MTM™
Advantages:
• Compatible with multiple extraction kits/platforms
– Ambion, Qiagen (including robotic extraction)
– Roche MagnaPure and LightCycler
– Life Technologies 7000/7500
– Others (i.e. BioMerieux, BioRad)
– Hain GenoType MTBDRplus Assay
• Facilitates POC detection or high throughput testing
(fixed or mobile diagnostic laboratories)
“From Sputum to Sequencing”
Transport
Swab in PS
Lab
Safe, ambient
temperature shipping
Sputum Specimen
Collection
PrimeStore MTM
Ion Torrent
Laboratory Preparation
•Extraction
•PCR
•Sample processing