Uppsala Longitudinal Study of Adult Men (ULSAM)

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Transcript Uppsala Longitudinal Study of Adult Men (ULSAM)

Uppsala Longitudinal Study of
Adult Men (ULSAM)
Age 50
1970 - 1973
N = 2322
Age 60
Age 70
Age 77
Age 88
1980 - 1985
1991 - 1995
1997 - 2001
2008 - 2009
N = 1860
N = 1221
N = 839
N = 354
Age 82
2003 - 2005
N = 530
2011-02-15
Participation
1.0
0.8
0.7
0.6
0.5
0.4
0.3
Cumulative Proportion Surviving
0.9
0.2
0.1
0.0
2011-02-15
Causes of death
By October 2010, 576 participants still were alive
 1746 participants have dead

2011-02-15
Hospital visits

74 individuals have never been at the hospital

46% off them are still alive
26% died over age of 65

From remaining 2248 participants only 24% are still
alive

They all together have visited hospital more than 23
000 times and have spent there over
200 000 days
2011-02-15
Use of hospital time 1970-2009
Total 218 847 days
2011-02-15
Measurements
2011-02-15
Genetic Analyses

First genetic study published in 1997

Over 4000 individual SNPs genotyped
2003 - 2010

In 2010 1221 individuals were genotyped
for ~180 000 SNPs using MetaboChip

In 2010 110 individuals were genotyped using
Illumina 1M chip
2011-02-15
Research activity

At least 50 researchers have been working with ULSAM
data under last three years

Over 150 research proposals have been approved by
ICTUS group from 2002

At least 220 articles have been published from ULSAM
initiation in 1970

27 doctoral theses have been defended
2011-02-15
Articles and theses based on
ULSAM cohort
2011-02-15