Nuclear Medicine division status Jean-Michel Poutissou 7

th

April 2011

Response to last year’s report

• • • • • • • • • Formal screening of new projects MHESA project status CCM status Expansion of wet laboratory space New recruitment Graduate students Solid target New imaging detectors MDS Nordion collaboration

November 29

th

retreat

• • • • • 15 months NRCan NISP grant for cyclotron production of 99m Tc received : Tight delivery deadlines. (March 2012) NSERC/CIHR grant ongoing (LS96) linked to the above.

MHESA new radiochemistry laboratory ( Joint project with Nordion) finally on track to be done soon ( TRIUMF`s share in the NRC budget to be expended by March 2011) GMP lab to be operational in December Radiochemistry research projects

NUMED FY 2011-12 Goals

• • 1) deliver on the NRCan project milestones 2) Deliver Tracers to our best partners like PPRC,PET centre, BCCA, UBC faculties ,Nordion, GE,..

• • We need: MHESA laboratory completion and operation GMP lab Operation

Other goals

• • Centre Comparative Medicine – New MicroPet /Spec scanner (CFI-Vesna) – Design of new pipeline connection to CCM Detector development: – New MicroPet/MRI scanner F.Retiere CFI proposal ( U.Manitoba/UBC/TRIUMF) – New “low” cost PET scanner development ( TRIUMF/BCCA) by Fabrice Retiere

Other projects under consideration

• • • Second CDR grant with Nordion Grant application with Genome BC Canadian Molecular Imaging Network centre of excellence proposal to be submit by August

JMP

Major Tasks Milestones Detailled design Tender & award contract Construction Hot cells delivery Install Commissioning GMP lab 005 GMP lab 005 operation GMP lab 007 upgrade ??

Funding approved Team organized Target development and testing Report to NRCan Cyclotron proposal .New building/TR19 relocation NU-MED Plan (2010-2015)

November 29, 2010

A 2010 J O J A 2011 J O J A 2012 J O J A 2013 J O J A 2014 J O J 2015 A ) NRU restart ommissioningl Legend: Research Infrastructure construction Science

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CFI proposal ( MPET/SPEct/ct

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Icfi PROPOSAL (MULTI MODAL FACILITY)

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piPELINE

NSERC/CIHR

Target Chemist

Deputy Division Head Core Programs

M. Adam

Principal Investigator Project Manager

NRCan

Nuclear Medicine

J.M. Poutissou

Special Advisor

T. Ruth

Deputy Division Head New Programs

P.Schaffer

NRCan Partners SeniorTarget Scientist New Infrastructure (P&S) Targets/Medical Isotope Production – Lead Scientist (BAE)

Cyclotron-Ops SeniorTarget Scientist

New Tracers Radiochemistry – Lead Scientist (BAE)

Target Chemist Target Engineer Electro mechanical Engineer

Electro mechanical Engineer Target Engineer

NRCan NISP project

New infrastructure

• GMP laboratory RCA005 upgrade: – 3 new hot cells ( Comecer) – 3 new chemistry boxes – New ventilation strategy – Clean room environment

GMP lab/personnel

MHESA laboratory

Centre for Comparative Medicine

• • • Construction on going Occupancy ( early 2012) CFI proposal for a Spect/Pet micro scanner by V.Sossi and P.Schaffer.

Major concern with PETA activist group New policy on disclosure of our LSPEC proposals and reports

Hiring plan

• • • • One extra Scientist ( radiochemist) One professional ( MHESA lab manager) Mike Adam will be replaced when he retires.

Several additions to the target group will be absorbed when the NRCan project terminates ( new soft funding or NRC bridge funding)

Students/ Postdocs

• • • • • • • • • • • • • • • • •

NRCan NISP project:

TOM MORLEY, PDF

PPRC/UBC PET Centre collaboration and the Good Manufacturing Practice Laboratory (GMP) upgrade:

G. TOPPING, PHD STUDENT (LS 94) 1 MSc STUDENT (VESNA) 3 PHD STUDENTS ( VESNA)

NORDION/TRIUMF collaboration:

ESTER BOROS, PHD STUDENT ERIC PRICE, PHD STUDENT CATERINA RAMOGIDA, PHD STUDENT JAQUELINE CAWTHRAY, PDF LISA MURPHY, PDF

Students/Postdocs

• • • • • • • • • • • • • • • • • • • •

BCCA-TRIUMF collaboration:

NONE AT THIS TIME

GE Healthcare Collaboration:

HUA YANG, PDF

CIHR/GENOME BC proposal (OLIGONUCLEOTIDES, MICRO-FLUIDICS):

JAMES INKSTER, PHD STUDENT KATE LIU, CO-OP STUDENT SAMAR HAROUN, PHD STUDENT ZARA SANAI, PHD STUDENT YING LI, PHD STUDENT M. POURSHIASIAN, PHD STUDENT

Collaboration with UBC’s Centre for Comparative Medicine (CCM):

TBA

MINet collaboration:

TBA

Policy for the SAP-EEC,MMS-EEC and LSPEC • • • • • • • In order to align TRIUMF policies on openness with other laboratories around the world, this document outlines in broad terms our new policies. Below EEC refers to all three committees.

1) All proposals submitted to TRIUMF will be available for view on the TRIUMF internal WEB in their entirety after review and if approved by the EEC.

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a. Only the title, author list, status, and short abstract (< 300 words) will be displayed on the public web pages.

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b. The EEC reports (and comments) are internal TRIUMF documents and will only be displayed on the internal TRIUMF web site. The full EEC report will be made available to the appropriate external funding committees.

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c. Proposals with private sector partners should follow Non Disclosure Agreements.(NDA)

2) Presentations to the EECs are open to everyone. Slides are available to the committee only. 3) Review committee members will treat the content of proposals as confidential. 4) Requests for information on proposals from outside the TRIUMF community will be granted only by the authors in consultation with TRIUMF communications. 5) Within 60 days of receiving beam time the spokesperson will provide to the Science Division for posting, on the public WEB pages, a short summary (< 300 words) of the experiment results. The summary of results will be used in the annual report. Details are disclosed at the discretion of the spokesperson. 6) The interpretation and application of this policy is the responsibility of the respective Division Head.