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Radia 7887 Cold Water-in-oil emulsifier INCI:Polyglycerol-3 Polyricinoleate & Sorbitan Isostearate HLB 4,2 & Single Emulsifier Liquid & EO Free Amber Coloured 1. W/O Properties 2. W/O Applications 3. Famous Examples 4. R7887 5. Formulations 1. W/O Properties •Skin protection •Long lasting moisturisation •Resemblance to the natural skin protective barrier •Improved spreading and penetration of active ingredients •Reduced preservative concentration 1. W/O Properties 2. W/O Applications 3. Famous Examples 4. R7887 5. Formulations 2. W/O Applications •Sun Screen milks, lotions and creams •Night creams •Creams & lotions for dry and sensitive skin •Skin protective baby creams •Massage milks 1. W/O Properties 2. W/O Applications 3. Famous examples 4. R7887 5. Formulations 3. Famous Examples Multi purpose cream Body Milk Sunscreen Diaper cream 1. W/O Properties 2. W/O Applications 3. Famous examples 4. R7887 5. Formulations 4. R7887.. •...is liquid and allows cold production = reduced cost! •...is based on natural raw materials & is PEG free. •...has no need for co-emulsifier single emulsifier •…is fit for high and low internal face •...provides emulsions with a glossy appearance •…functions at low levels (≥1%) 1. W/O Properties 2. W/O Applications 3. Famous examples 4. R7887 •Solid emulsifier requires temperature (=cost) input. T (°C) 1 2 3 Hot Process a. Cold Process b. Emollients c. Single Emulsifier 5. Formulations +/- 80 4 = Cost 20 Homogenize 5 1. W/O Properties 2. W/O Applications 3. Famous examples 4. R7887 •R7887 doesn’t require heating = possible cost reduction! T(C°) a. Cold Process b. Emollients c. Single Emulsifier 5. 1 2 3 4 Homogenize Formulations 20 5 1. W/O Properties 2. W/O Applications 3. Famous examples •Potential cost reduction thanks to cold proces. Hot Proces vs Cold Proces Weighing and mixing Minutes Weighing mixing 20 4. 5. R7887 Heating Homogenisation a. Cold Process b. Emollients C. Single Emulsifier Homogenisation Addition of other raw materials Cooling & agitation Filling Time loss during cooling / Addition of other raw materials / Cooling to room tempurature / Filling / Formulations 40 60 80 100 120 140 160 1. W/O Properties 2. W/O Applications 3. Famous examples 4. R7887 a. Cold Process b. Emollients c. Single Emulsifier 5. Formulations b. Emollients influence formulation. • % water => Viscosity Formulation • Viscosity emollients • Homogenisation => Viscosity Formulation => Stability (& Viscosity) Formulation 1. W/O Properties 2. W/O Applications 3. Famous examples 4. R7887 a. Cold Process b. Emollients c. Single Emulsifier 5. c. Single Emulsifier.: Test protocol Test formulation W/O Oilphase Oil Emulsifier 10 or 18 or 30 1 or 3.5 Waterphase Formulations Glycerol MgSO4.7H2O Preservative Water 4 0,7 q.s. to 100% Low external phase = 10% High external phase = 30% Low surfactant = 1% High surfactant = 3.5% Centrifuge stability (3x15min @ 4000rpm) Temperature stability 1week @ 50°C 2months@ 40°C 3 months@ RT Viscosity stability ( mPas) Brookfield 10rpm, 1 minute, LVT spindle After 1 day After 3 months appearance Visual aspect 1. W/O Properties 2. W/O Applications 3. Famous examples 4. R7887 a. Cold Process b. Emollients c. Single Emulsifier 5. Formulations c. Single Emulsifier.: Conclusions •1% emulsifier is stable for MCT and paraffin oils (18%). • 3,5% emulsfier is stable for MCT, sunflower oil and paraffin oils. Separate esters are being tested. •Highest viscosity and synergy is obtained by using sunflower oil. •Internal phases till 82% were achieved. 5. Formulations Low Cost W/O protective cream HP11-22-2 •Phase •Ingredient •INCI •A •Radia 7887 •Polyglycerol-3 Polyricinoleate & Sorbitan Isostearate •3.6 •Radia 7373 •Triisostearin •0.5 •Radia 7363 •Triolein (= Sunflower oil) •18 •Glycerin 4810 •Glycerin •water •Aqua •B •C •% w/w •4 •To 100 •Mg.SO4.7H2O •0.8 •preservative •0.7 Viscosity : 121000 mPa.s (Brookfield RV, spindle 7, rpm 10, 1 min.) Assessment: Rich protective cream, high viscosity, film forming , good spreading 5. Formulations W/O soft body cream/Lotion HP03-54-3 •Phase •Ingredient •INCI •A •Radia 7887 •Polyglycerol-3 Polyricinoleate & Sorbitan Isostearate •4 •Radia 7208 •Propylene Glycol Dicaprylate/Dicaprate •2 •Radia 7732 •Isopropyl Palmitate •B •C •% w/w •11 •Sweet almond oil •2 •Avocado oil •2 •Glycerin 4810 •Glycerin •water •Aqua •3 •To 100 •Mg.SO4.7H2O •0.5 •preservative •0.7 •Viscosity ,35000 mPa.s (Brookfield RV, spindle 6, rpm 10, 1 min.) •Assessment: Rich day lotion, nice, soft skinfeel, smooth afterfeel , good spreading 5. Formulations Low Cost Protective baby cream •Phase •Ingredient •INCI •A •Radia 7887 •Polyglycerol-3 Polyricinoleate & Sorbitan Isostearate HP11-12-1 •Paraffin Oil •B •C •% w/w •3,6 •15 •Radia 7373 •Triisostearin •0,5 •Radia 7500 •Cetyl Palmitate •2 •Glycerin 4810 •Glycerin •3 •water •Aqua •To 100 •Mg.SO4.7H2O •0.5 •preservative •0.7 •ZnO •10 •Viscosity ,35000 mPa.s (Brookfield RV, spindle 6, rpm 10, 1 min.) •Assessment: Rich day lotion, nice, soft skinfeel, smooth afterfeel , good spreading