Transcript Post Graduate Quiz

Postgraduate Quiz
Instructions
• All slides carry equal marks
• There is no negative marking
• Each slide will be given 30 seconds to 1 minute
after reading out the question
All the Best!
Q1.
• 18 years female presented with high grade fever
• She was a known case of HIV
PBF
• Identify the abnormality
• Advice Cytochemistry
Q2.
• 48 years ♀ presented with weakness & variable cytopenias
• She was being treated for depression
Trephine biopsy
• Identify the abnormality
• Advice Confirmatory test
Q3.
• 15 years male presented with fever with chills
PBF
• Identify the abnormality
• Name the Vector
Q4.
HPLC graph from BioRad Classic
• Identify the abnormality
• What will be the expected clinical
phenotype?
Q5.
• Identify the preparation
• Enumerate 2 conditions where the test may be positive
Q6.
64 year male with
splenomegaly.
• Interpret the flow cytometry
• Suggest a molecular
confirmatory test for this
disease?
Q8.
Describe the morphology of the cell in the peripheral blood film.
Mention 2 conditions where this can be seen
Q9.
Normal
Patient
Spot the abnormality
A
B
Name 2 conditions where the
abnormality can be seen
Methemoglobin levels:
7.5% & after blood transfusion- 0.3%
?
Father (Case II)
Son (Case I )
OxyHb is capable of reversible oxygenation; its heme iron is in the
reduced (or ferrous) state
MetHb: Heme oxidizes spontaneously & is incapable of reversible
oxygenation
Q10.
• 21 years ♀ presented with gum bleeds & skin nodule
• Blood counts showed increased TLC with thrombocytopenia
BM aspirate
1. Suggest possible diagnosis
2. Suggest associated
cytogenetic abnormality
• 2 year male presented with epistaxis
• Coagulogram: PT- 13 sec, APTT-27 secs, N platelets
Platelet aggregation
Physiological Agonists
ADP
10mM
Collagen
2mg/ml Epinephrine
10mM Arachidonic acid
0.5mM
• What is the diagnosis?
• What will you find in a finger prick smear
• What is the mode of inheritance of the condition?
Q6.
Q 10.
• Name any 2 agents
that can be used for
decalcification of bone
marrow biopsies.
Q 11.
Kidney biopsy from a 33 yr
female with seizures and
acute renal failure following
fever for a day.
• What is the diagnosis?
• What will the PT & PTTK
results?
• Mention one therapeutic
modality.
Two siblings ages 3 & 5 years presented with
pallor and mild hemolytic facies
BM was done to investigate cause of anemia
Q 12.
BM aspirate
Descibe the BM findings
Any confirmatory tests?
Q 13.
6 months child presented with progressive anemia and splenomegaly
Screening for thalassemia was negative
Trephine biopsy
Descibe the findings
Any special stains?
Q 14.
• 13 yrs male presented with fever & echymosis for 3 days
• Blood cell counts showed anemia, leucocytosis and thrombocytopenia
Describe the BM findings and interpret the MPO stain
BM
MPO
Q 15.
Describe the BM aspirate finding