Transcript Module 6 – Rotavirus vaccine AEFI monitoring ppt, 530kb

Training for rotavirus vaccine introduction
Module 6
Rotavirus vaccine AEFI
monitoring
Learning objectives
 At the end of the module, the participants will be
able to:
– Identify adverse events following immunization
(AEFIs), including intussusception (IS)
– Explain how to report AEFIs
 Duration
– 15’
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Rotavirus vaccine AEFI monitoring, Module 6 I 24 July 2016
Key issues
1 What are the AEFIs of
rotavirus vaccine?
2 What is intussusception (IS)?
3 How to report an AEFI?
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Rotavirus vaccine AEFI monitoring, Module 6 I 24 July 2016
What is an AEFI?
AEFI= Adverse event following immunization
A medical incident that takes place after an immunization,
causes concern, and is believed to be caused by
immunization
AEFI can be categorized into
•Vaccine reaction
•Programme error
•Coincidental
•Injection reaction
•Unknown
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Rotavirus vaccine AEFI monitoring, Module 6 I 24 July 2016
What about Intussusception (IS)? (1/2)
 In the past, the first rotavirus vaccines (RotashieldTM)
caused IS, a serious but very rare bowel obstruction
 With the new rotavirus vaccines, there seems to be a very
small increased risk of IS in infants following rotavirus
vaccination
 The increased risk appears to occur mainly in the first 1- 7
days following the first dose of rotavirus vaccine
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Rotavirus vaccine AEFI monitoring, Module 6 I 24 July 2016
Risk of IS against risk of rotavirus
infection
 Whether the new rotavirus vaccine affects the overall
incidence of IS has not yet been established
 The risk of IS after rotavirus vaccination is much lower than
the risk of severe rotavirus disease in unvaccinated
children!
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Rotavirus vaccine AEFI monitoring, Module 6 I 24 July 2016
How to report a AEFI? (1/2)
 Report the identified AEFI through existing AEFI reporting
systems established by national immunization programs
Suspected signs
or symptoms
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Community, district, and
regional levels
Rotavirus vaccine AEFI monitoring, Module 6 I 24 July 2016
National
authorities
How to report an AEFI? (2/2)
 AEFI report should contain
–
–
–
–
Client information
Immunization event(s) description
Adverse event(s) description
Relevant medical and treatment
history
– Associated event(s)
– Reporter details
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Rotavirus vaccine AEFI monitoring, Module 6 I 24 July 2016
Key messages
 The current safety profile of rotavirus vaccines is good
 Many infants who get the rotavirus vaccine do not
experience any side effects
 The risk of IS after rotavirus vaccination is much lower
than the risk of severe rotavirus disease in unvaccinated
children
 AEFIs should be reported through the existing AEFI
reporting systems/forms
 Reassure the caretaker- Admit uncertainty, investigate
fully, and keep the community informed
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Rotavirus vaccine AEFI monitoring, Module 6 I 24 July 2016
End of module
Thank you
for your attention!
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Rotavirus vaccine AEFI monitoring, Module 6 I 24 July 2016