Transcript Lesson 9
M.Tech. (CS), Semester III, Course B50 Functional Brain Signal Processing: EEG & fMRI Lesson 9 Kaushik Majumdar Indian Statistical Institute Bangalore Center [email protected] Buzsaki et al., Nat. Rev. Neurosci., 13: 407 – 420, 2012 Bentivogilo et al., Epileptic Disorders, 5: S27 – S34, 2003 Action Potential, LFP, ECoG, EEG Buzsaki et al., Nat. Rev. Neurosci., 13: 407 – 420, 2012 Action Potential, LFP, ECoG, EEG (cont.) or ECoG Buzsaki, Nat. Neurosci., 7(5): 446 – 451, 2004 LFP Acquisition http://www.ece.unm.edu/~vcalhoun/courses/fMRI_Spring07/Lecture02_IntroTofMRI.pdf Hemodynamic Response http://www.ece.unm.edu/~vcalhoun/courses/fMRI_Spring07/Lecture02_IntroTofMRI.pdf MRI Machine Logothetis & Wandell, Annu. Rev. Physiol., 66: 735 – 769, 2004 BOLD vs. LFP http://www.ece.unm.edu/~vcalhoun/courses/fMRI_Spring07/Lecture02_IntroTofMRI.pdf Blood Oxygen Level Dependent Signal HbO2 is dimagnetic. Deoxy-Hb is paramagnetic. Anatomical MRI Kandel et al., Principles of Neural Science, 4e, 2000 Elements of MRI Physics Pooley, 2005 Larmor Equation Gyromagnetic ratio is nucleus dependent. For hydrogen it is 42.6 MHz/T. Pooley, 2005 Radio Frequency (RF) Pulse T1 relaxation time Pooley, 2005 Tissue Contrast Maximization by T1 Relaxation Kandel et al., Principles of Neural Science, 4e, 2000 Relaxation Process and T2 Relaxation Kandel et al., Principles of Neural Science, 4e, 2000 T1 and T2 Weighting Kandel et al., Principles of Neural Science, 4e, 2000 T1, T2 Time Constants in ms at 1 Tesla for Different Tissues Noll, 2001 One Dimensional Frequency Encoding B(x) = B0 + G.x ƒ(x) = γ(B0 + G.x) Kandel et al., Principles of Neural Science, 4e, 2000 Slice Location Kandel et al., Principles of Neural Science, 4e, 2000 Slice Location (cont.) Buxton, 2009 T1 and T2 Relaxation Time Kandel et al., Principles of Neural Science, 4e, 2000 Functional Magnetic Resonance Imaging or T2* Relaxation Imaging Pooley, 2005 T2 and T2* Dephasing References G. Buzsaki, C. A. Anastassiou and C. Koch, The origin of extracellular fields and currents – EEG, ECoG, LFP and spikes, Nat. Rev. Neurosci., 13: 407 – 420, 2012. E. R. Kandel, J. H. Schwartz and T. M. Jessel, Principles of Neural Science, 4e, McGraw Hill, New York, 2000, p. 370 – 374. R. A. Pooley, Fundamental physics of MR imaging, RadioGraphics, 25(4): 1087 – 1099, 2005. References (cont.) D. C. Noll, A primer on MRI and functional MRI, available online at http://www.cs.ucsb.edu/~mturk/imaging/Misc/ MRI%20primer.pdf R. B. Buxton, Introduction to Functional Magnetic Resonance Imaging, 2e, Cambridge University Press, Cambridge, UK, 2009. THANK YOU This lecture is available at http://www.isibang.ac.in/~kaushik