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Dosimetry measurements with an intra-operative x-ray device Eaton, D. J., & Duck, S. (2010). Dosimetry measurements with an intraoperative x-ray device. Physics in medicine and biology, 55(12), N359. Chairman: Shih-Jhong Chen Presenter： Cheng-bang Shih Adviser:：Dr.Yi-Chun Du Date: 2015.05.13 1 Outline Introduction Materials and methods Results Conclusion 2 生醫系統整合實驗室 Integrated Biomedical System Laboratory Introduction 3 生醫系統整合實驗室 Integrated Biomedical System Laboratory Introduction • TARGIT , it uses a compact mobile x-ray unit, the Carl Zeiss INTRABEAM system, to deliver radiation from inside the tumour cavity. • The device accelerates electrons to a maximum energy of 50 keV. 4 生醫系統整合實驗室 Integrated Biomedical System Laboratory Introduction For breast treatments is a solid spherical applicator is attached to the probe 5 生醫系統整合實驗室 Integrated Biomedical System Laboratory Introduction Aim of this study: – measure dosimetric data required by the IPEMB code of practice for the source with applicators attached. – compare the dosimetry of the INTRABEAM system to a superficial therapy x-ray unit in our centre. 6 生醫系統整合實驗室 Integrated Biomedical System Laboratory Materials and methods 7 生醫系統整合實驗室 Integrated Biomedical System Laboratory Materials and methods HVL • Applicators with diameters of 3.0 cm and below have a metal sheath around the inside surface of this channel • Ionization chamber was positioned 1.0 m from the x-ray source and a 1.5 mm thick lead sheet with 4 cm aperture in the centre was placed equidistant between the source and chamber. 8 生醫系統整合實驗室 Integrated Biomedical System Laboratory Materials and methods Determination of NK • An applicator size of 1.5 cm. • A cone size of 4.0 cm diameter with the Therapax 3. • The end of the cone or applicator was positioned approximately 3 cm. • without moving the x-ray source. 9 生醫系統整合實驗室 Integrated Biomedical System Laboratory Materials and methods Determination of kch (1) (2) (3) Mair = the chamber reading in air corrected to standard temperature and pressure Bw = the backscatter factor Mphan = chamber reading in a full scatter phantom corrected to standard temperature and pressure 10 生醫系統整合實驗室 Integrated Biomedical System Laboratory Materials and methods Depth dose curves 11 生醫系統整合實驗室 Integrated Biomedical System Laboratory Results 12 生醫系統整合實驗室 Integrated Biomedical System Laboratory Results HVL 13 生醫系統整合實驗室 Integrated Biomedical System Laboratory Results Determination of NK 14 生醫系統整合實驗室 Integrated Biomedical System Laboratory Results Determination of kch 15 生醫系統整合實驗室 Integrated Biomedical System Laboratory Results Depth dose curves 16 生醫系統整合實驗室 Integrated Biomedical System Laboratory Conclusion 17 生醫系統整合實驗室 Integrated Biomedical System Laboratory Conclusion • This study has described aspects of the dosimetry of the system with the spherical applicators used clinically for breast treatments. • This study reduces the technical limitations in these measurements. 18 生醫系統整合實驗室 Integrated Biomedical System Laboratory Thank you for your attention! http://faculty.stust.edu.tw/~terrydu/ 生醫系統整合實驗室 Integrated Biomedical System Laboratory 19