Transcript Nitro

NITROGLYCERIN
Temple College
EMS Professions
ECA
Nitroglycerin
• Mechanism of Action
–Relaxes vascular smooth muscle
Nitroglycerin
• Effects
–Dilates blood vesels
–Decreased pre-load
–Decreased after-load
–Increased blood flow to Ischemic
Myocardium
Nitroglycerin
• Indications
–Ischemic Chest Pain
Nitroglycerin
• Contraindications
–BP<100mm Hg
–ED drugs in past 24-48 hours
Nitroglycerin
• Forms
–Tablet
–Spray
–Patch
–Paste
Nitroglycerin
Nitroglycerin
• Dose
–0.4mg sublingual
• Tablet or Metered-dose Spray
• May repeat at 5 minute
intervals
–Patch Varies
–Paste Varies
Nitroglycerin
• Side Effects
– Hypotension
– Reflex Tachycardia
– Headache
– N/V
– Flushing
– Dizziness
Nitroglycerin
• Comments
–Do not give if patient is standing
–If tablet form - Protect potency
• Store in original brown bottle
• Keep tightly sealed
• Protect from light, air, heat
• Secure new supply every 4 - 6 months
Nitroglycerin
• Potent Nitroglycerin
–Headache
–Burning sensation under tongue