Transcript Powerpoint Presentation: Respiration and the Kreb's Cycle

RESPIRATION &
OXIDATION
GLYCOLYSIS

Step 1: Phosphorylation:
Glucose + 2ATP  Fructose 1,6-diphosphate + 2ADP

Step 2: Splitting 6C sugar to 2 x 3C
sugars:
Fructose 1,6-diphosphate  2 Glyceraldehyde Phosphate

Step 3: Energy release:
2 Glyceraldehyde Phosphate  2 Pyruvate (oxypropanoate)
8ADP
© 2010 Paul Billiet ODWS
8ATP
KREB'S CYCLE
Enzymes located in the inner matrix of
mitochondria (in eukaryotes)
Note: Number of mitochondria per cell =
activity of the cell On average 1000 per cell
(between 20 and 10 000)
© 2010 Paul Billiet ODWS
Inner matrix
Cristae
Inter membrane space
outer
membrane
Mitochondrial
envelope
inner
membrane
Image credit: Mitochondria
Step 1: Synthesising ACETYL
COENZYME A
Also produced from
fatty acids and
amino acids
3ADP 3ATP
Pyruvate  Acetyl CoA + CO2
(3C)
(2C)
(1C)
CYTOPLASM  MITOCHONDRIA
© 2010 Paul Billiet ODWS
Step 2: Oxidising Acetyl CoA
back to the cytoplasm
Acetyl CoA + Oxaloacetate
(2C)
(4C)
Breathed out or used
by chloroplasts
Citrate + CoA
(6C)
KREB'S
CYCLE
2CO2
4 x 1/2O2
4H2O
12ATP 12ADP
© 2010 Paul Billiet ODWS
The Kreb's Cycle was discovered by using
inhibitors and isolating enzymes from
tissues rich in mitochondria
 Total ATP from 1 molecule of glucose
in AEROBIC CONDITIONS
 Glycolysis
- 2 (phosphorylation) +8
Kreb's Cycle
+30 (2x15)
TOTAL
36 ATP

© 2010 Paul Billiet ODWS