Transcript Chapter 43: Amines

Chapter 43
Amines
Purpose
• The object of this experiment is to identify an
unknown amine or amine salt. First test to check
solubility. Second experiment represents a Hinsberg
test for distinguishing between primary, secondary
and tertiary amines.
Hinsberg Test
• In Hinsberg test, the sulfonamides are distinguishable
because the derivative from a primary amine has an
acidic hydrogen, which renders the resulting salt
soluble in H2O. Whereas the sulfonamide from the
secondary amine is insoluble.
Comments
• Follow pp. 588-590 (microscale).
• Follow the lab handout for all experimental
procedures. Wearing rubber gloves is
necessary during this lab. You will work with
toxic and corrosive compounds.
• Use solubility and Hinsberg test to figure
out the unknown structures.
Safety
• Amines are toxic and have a characteristic
smell: work in the hood. Do not swallow, do
not inhale and avoid contact with eyes and
skin. Wear gloves and handle with caution.
• Benzenesulfonyl chloride is corrosive, avoid
contact with skin and eyes, wear gloves and
goggles, use caution.