Transcript tutorial.ppt

Revision on intestinal
protozoa
Feature of intestinal and
tissue protozoa:
• Entamoeba histolytica, G.lamblia
are motile organisms that multiply
and encysted in lumen of intestinal
tract. they form cyst which
excreted in faces.
• Invasive strains of E histolytica
multiply in intestinal wall.
• T.vaginalis is motile and multiplies
in the urogenital tract cyst forms
are unknown.
• Cryptospordium multiply
intracellular in cells. It produces
oocysts which are excreted in
feces.
• T.gondii muliply intracelluler in
reticuloendothelial cell and cell of
brain and other organs of body.
•
•
•
•
Infection is by ingesting
cysts (E.histolytica, G.lamblia) or
oocyst (Cryptosporidium,T.gondii)
in food,water,or from hands
contaminated with infected feces.
T.gondii can also be transmitted
congenitally.
And by ingesting the parasites in undercooked meat (toxoplasma cyst) of
intermediate hosts.
• T.vaginalis is transmitted
sexually (no cyst).
Humans are important hosts of
E. histolytica, G.lamblia and
T.vaginalis.
Animal are natural definitive
hosts of Cryptosporidium and
T.gondii .
Laboratory confirmation of
• E.histolytica infection is by finding
amoebae or cysts in feces or by
detecting antibodies in serum
(invasive amoebiasis)
• Giardiasis diagnosed by finding
motile flagellates or cysts in feces
or flagellates in duodenal
aspirates.
• Infection with Cryptosporidium is
diagnosed by finding oocyst in
feces
• Toxoplasmosis is usually diagnosed
serologically.
• T. vaginalis infection is usually
confirmed by detecting flagellates
in vaginal or uretheral discharge
or urine.