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INTESTINAL OBSTRUCTION By: Brig Mushahid Aslam “Neither sun shall rise nor set on patient of intestinal obstruction” Sequence Duodenal Atresia Jejuno-ileal Atresia Meconium Ileus Definitions Agenesis Aplasia Atresia Hypoplasia Hyperplasia Dysplasia absence of organ or primordium absence of organ due to failure of primordium absence of an opening incomplete development of an organ overdevelopment of an organ abnormal cell organization Duodenal Atresia 1: 5000 Associated Anomalies Down’s Syndrome 30 % Congenital Heart Diseases Malrotation Anorectal Malformations Congenital Atresia of the Small Intestine “Vascular Accidents” blood supply to a region of the bowel is compromised and a segment “dies”, resulting in narrowing or complete loss of that region 50% 20% 20% a region of the bowel is lost a fibrous cord remains narrowing, with a thin diaphragm separating the larger and smaller pieces of bowel N.B. stenoses (5%) and multiple atresias (5%) account for the remaining defects Presentation Antenatal USG Polyhydramnios Distended stomach and 1st part Duodenum Newborn Feeding Intolerance Bilious Vomiting Scaphoid Abdomen Failure to pass Meconium Association Types Type I: Complete membrane obstructing the lumen Type II: A pouch with a fibrous cord connecting to the distal duodenum Type III: blind-ending pouch with no connection to the distal duodenum Investigations Management NPO Nasogastric aspiration Intravenous fluids Antibiotics Surgery 5’ Hs Hypothermia Hypoxia Hypovolemia Hypoglycaemia Hypoprothrombinaemia Management Management Jejuno-ileal Atresia 1/2000 Vomiting Abdominal Distension Failure to pass meconium Pathogenesis Mesenteric vascular accidents during early embryologic development infarction organization + resorption of the necrotic segment The bowel segment distal to the atresia may contain meconium, indicating previous continuity of the intestine Types Types Types “APPLE PEEL” ATRESIA CONGENITAL MIDGUT ATRESIA Investigations Management Management Meconium Ieus 30 % intestinal obstruction Associated Anomalies Cystic Fibrosis 15% Atresia Malrotation Presentation Newborn Feeding Intolerance Bilious Vomiting Abdominal Distention Failure to pass Meconium Investigations Treatment Hypertonic Enema Washouts Gastrograffin 25-50 % Effective 30-60 % cases N-Acetyl cysteine 10 % Management