Transcript NanoIR AFM Rice et al, Optics Lett,

NanoIR
AFM
sample
Height (nm)
cantilever
400
300
AFM
NanoIR
200
100
0
PPLN
280
4
240
200
160
Opto-acou (mV)
Elliptical
mirror
AFM laser
Quadrant
detector
5
6
7
8
9
Lateral Position (mm)
Nd:YAG
AFM
NanoIR
Rice et al,
Optics Lett,
submitted.
Absorption (au)
NanoIR
FTIR
2800 2900 3000
Wavenumbers (cm-1)
Future
Experimental equipment
Uninfected
Heavily
infected
• NanoIR Requirements
• Applications
NanoIR
Coli bacteria
& phage virus
- Heterogeneous systems
- Bacteria, viruses, cells
• Future developments
AFM Raman
single S.
epidermidis cells
CLIO (2007)
Ultramicroscopy,
107, 1194, (2007)
Nano flouresence
BIO systems
Science, 316, 1153 (2007)
E
The Drosophila
coiled-coil
domainprotein
Bruchpilot (BRP)
 h
APL, 86, 213103 (2005)
500 nm
Science, 312,
1051 (2006)
Future directions
• Requirements
- Enables classical microscopy
• Applications
- Cells, nanoarchitectures (neurons)
- Hybrid systems
• Future developments
DNA
template
NQD
NQD
DNA
template
200 nm
200 nm
Nano Lett., 6, 1502 (2006)
Conclude
• Applying nano-imaging
- Cell processes
- Nano bio architectures (ex. Neurons)
• Collaboration
- College of life sciences
- Conway Institute
- External centres