Transcript VASCULITIS Dr SAMI BAHLAS

VASCULITIS
Dr SAMI BAHLAS
CLASSIFICATION
CLASSIFICATION
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Granulomatous; GCA, Takayasu, Wegener,
Churg-Strauss & Isolated CNS.
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Immune Complex; PAN, MPA, Kawasaki,
hypersensitivity vasculitis & HSP.
PAN
PAN
PAN
PAN
PAN
GCA
GCA
GCA
GCA
TAKAYASU’S
CHRUG-STRAUSS
WGENER`S
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Granulomatous inflammation.
GN.
cANCA.
WGENER`S
BEHCET’S
KAWASAKI DISEASE
KAWASAKI DISEASE
KAWASAKI DISEASE
HENOCH-SCHONLEIN
CUTANEOUS VASCULITIS
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Drugs
Infections
HSP
Autoimmune
Malignancy
Cryoglobulinemia
Urticarial vasculitis
URTICARIAL VASCULITIS
CRYOGLOBULINAEMIA
Type I
Type II
single homogeneous monolonal IG.
mixed cryoglobulins with a monoclonal component
against a polyclonal IgG.
Type III
mixed polyclonal that are heterogenous.
CRYOGLOBULINAEMIA
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Unmixed (I)L ; myeloma, lymphoma,
waldenstrom, essential  raynauds,
thrombosis, ulceration.
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Mixed (II &III) ; CIC, CTD, infection,
essential  purpura, arthritis, raynaud,
renal, neuropathy.