Transcript - flubendiamide -

BELT 4 SC Insecticide for Cotton
Beltwide Cotton Conferences, 2007
- flubendiamide -
1
The Next Generation in Lepidoptera
Pest Management in Cotton
Alan Hopkins, Shane Hand,
Jon Mixson and Steve Krueger
BELT 4 SC Insecticide for Cotton
Chemical Properties = The Nuts ‘n Bolts
 1st compound of new chemical class (phthalic acid diamides)
 Newly discovered mode of action = interrupts the Ca2+ balance as an
ingested stomach poison
 Considered harmless to pollinators and beneficials
 Environmentally-friendly with favorable tox, ecotox, e-fate profile
 IPM / IRM friendly
Beltwide Cotton Conferences, 2007

REI*
I
OH C
3
= 12 hours (all crops)
N
H
O
 PHI* = 1 day (all veggies)
 Apps by air / ground / chemigation*
CH3
SO2CH3
HN
 Highly rainfast (once dry)
 Low rates = low env. loading
 Excellent crop safety
2
* Proposed labels
H3C
CF
CF3
CF3
BELT 4 SC Insecticide for Cotton
Beltwide Cotton Conferences, 2007
3
Biological Characteristics
Target Pests:
Other
Target Crops:
Lepidoptera (broad-spectrum)
– evaluating activity on secondary pests
The active ingredient will also be registered for use in
vegetables, grapes, fruits, tree nuts, citrus, and corn
Mode of action:
=> unmatched larvicidal activity
=> orally-ingested intoxicant
=> fast acting: rapid cessation of feeding (hrs)
=> long lasting: rainfast and residual (weeks)
=> novel biochemical target
=> Ca2+ balance, stomach poison
=> no known cross-resistance
Formulation:
BELT 4SC in cotton
BELT 4 SC Insecticide for Cotton
Beltwide Cotton Conferences, 2007
4
Insects Controlled
 Highly active against larval stages of
a broad range of lepidopteran pests.
 Includes a host of difficult to control
pests, including armyworm complex,
looper complex, bollworm and
budworm.
BELT 4 SC Insecticide for Cotton
Beltwide Cotton Conferences, 2007
5
Registration Timeline
Data Completion:
November, 2005
EPA Submission:
April, 2006
Anticipated Reg:
2007
Full US Launch:
2008
BELT 4 SC Insecticide for Cotton
% Control of Fall Armyworm
120
70g (2oz)
88g (2.5oz)
Tracer (2oz)
96
100
84
77
80
% Control
105g (3oz)
85
89
86
95
89
89
84
73
84
79
77
77
70
68
65
63
60
60
Beltwide Cotton Conferences, 2007
40
6
20
0
1
1 = Belt 4SC 70g (2oz)
2 = Belt 4SC 88g (2.5oz)
3 = Belt 4SC 105g (3oz)
4 = Tracer 2oz
2
3
4
7 DAA
14 DAA, 4 DAB
21 DAA, 11 DAB
24 DAA, 14 DAB, 3 DAC
30 DAA, 20 DAB, 9 DAC
Arlene Kurakowa,
Bayer CropScience
Fresno, California
BELT 4 SC Insecticide for Cotton
% Control of Fall Armyworm
120
70g (2oz)
88g (2.5oz)
105g (3oz)
Tracer (2oz)
100
80
78
79
81
1
2
3
4
% Control
80
60
Beltwide Cotton Conferences, 2007
40
7
20
0
1 = Belt 4SC 70g (2oz)
2 = Belt 4SC 88g (2.5oz)
3 = Belt 4SC 105g (3oz)
4 = Tracer 2oz
Seasonal Mean for Evaluations
7DAA and Beyond
Arlene Kurakowa,
Bayer CropScience
Fresno, California
BELT 4 SC Insecticide for Cotton
% Control of Bollworm and Tobacco Budworm
(Evaluation of Damaged Squares)
120
70g (2oz)
100
88g (2.5oz)
105g (3oz)
95
96
98
1
2
3
Tracer (2oz)
94
% Control
80
60
Beltwide Cotton Conferences, 2007
40
8
20
0
1 = Belt 4SC 70g (2oz)
2 = Belt 4SC 88g (2.5oz)
3 = Belt 4SC 105g (3oz)
4 = Tracer 2oz
Evaluation 9 days
after third application
4
John Curtis,
Bayer CropScience
Molino, FL
BELT 4 SC Insecticide for Cotton
(Dr. Gus Lorenz, University of Arkansas)
Untreated Check
BELT (2 oz)
BELT (3 oz)
TRACER (2.5 oz)
Total Number of Larvae
BELT (2.5 oz)
Number of Larvae
30
20
10
3/
20
0
7/
15 7
/2
00
7/
17 7
/2
00
7/
19 7
/2
00
7/
21 7
/2
00
7/
23 7
/2
00
7/
25 7
/2
00
7/
27 7
/2
00
7/
29 7
/2
00
7/
31 7
/2
00
7
8/
2/
20
07
8/
4/
20
07
8/
6/
20
07
8/
8/
20
07
0
7/
1
Beltwide Cotton Conferences, 2007
9
Influence on Seasonal Heliothine Larvae
Applications on July 10 and 20. Data collected from 6 evaluations.
BELT 4 SC Insecticide for Cotton
(Dr. Gus Lorenz, University of Arkansas)
Untreated Check
BELT (3 oz)
BELT (2 oz)
TRACER (2.5 oz)
Total Number of Larvae
BELT (2.5 oz)
DENIM (8 oz)
STEWARD (1.6 oz)
Number of Larvae
30
20
10
3/
20
0
7/
15 7
/2
00
7/
17 7
/2
00
7/
19 7
/2
00
7/
21 7
/2
00
7/
23 7
/2
00
7/
25 7
/2
00
7/
27 7
/2
00
7/
29 7
/2
00
7/
31 7
/2
00
7
8/
2/
20
07
8/
4/
20
07
8/
6/
20
07
8/
8/
20
07
0
7/
1
Beltwide Cotton Conferences, 2007
10
Influence on Seasonal Heliothine Larvae
Applications on July 10 and 20. Data collected from 6 evaluations.
(Dr. Gus Lorenz, University of Arkansas)
Untreated Check
BELT (2 oz)
BELT (3 oz)
TRACER (2.5 oz)
Total Number of Larvae
BELT (2.5 oz)
80
60
40
20
0
3/
20
0
7/
15 7
/2
00
7/
17 7
/2
00
7/
19 7
/2
00
7/
21 7
/2
00
7/
23 7
/2
00
7/
25 7
/2
00
7/
27 7
/2
00
7/
29 7
/2
00
7/
31 7
/2
00
7
8/
2/
20
07
8/
4/
20
07
8/
6/
20
07
8/
8/
20
07
Number of Damaged Fruit
100
7/
1
BELT 4 SC Insecticide for Cotton
Beltwide Cotton Conferences, 2007
11
Influence on Seasonal Heliothine Damage
Applications on July 10 and 20. Data collected from 6 evaluations.
(Dr. Gus Lorenz, University of Arkansas)
Untreated Check
BELT (3 oz)
BELT (2 oz)
TRACER (2.5 oz)
Total Number of Larvae
BELT (2.5 oz)
DENIM (8 oz)
STEWARD (1.6 oz)
80
60
40
20
0
3/
20
0
7/
15 7
/2
00
7/
17 7
/2
00
7/
19 7
/2
00
7/
21 7
/2
00
7/
23 7
/2
00
7/
25 7
/2
00
7/
27 7
/2
00
7/
29 7
/2
00
7/
31 7
/2
00
7
8/
2/
20
07
8/
4/
20
07
8/
6/
20
07
8/
8/
20
07
Number of Damaged Fruit
100
7/
1
BELT 4 SC Insecticide for Cotton
Beltwide Cotton Conferences, 2007
12
Influence on Seasonal Heliothine Damage
Applications on July 10 and 20. Data collected from 6 evaluations.
BELT 4 SC Insecticide for Cotton
Beltwide Cotton Conferences, 2007
13
Summary
 Flubendiamide is the first compound of the new
chemical class: phthalic acid diamides.
 Newly discovered mode of action: interrupts the
Ca2+ balance as an ingested stomach poison.
 Bayer CropScience expects registration of the
active ingredient in several crops including cotton.
 Provides excellent control of several lepidopteran
pests of cotton, including the Heliothine complex.
 Registration is expected in time for launch in 2008.
Beltwide Cotton Conferences, 2007
14
BELT 4 SC Insecticide for Cotton