Transcript brown eyes

Student #1 & Student #2 1 st Period Biology Mr. Teacher

Student #1 – blue eyes Father – blue eyes Paternal Grandparents Mother – green eyes Maternal Grandparents Grandfather – green eyes Grandmother – blue eyes Grandfather – brown eyes Grandmother – green eyes

Punnett Square for Student #1

Student #1’s Mother has allele combination bbGG and Father has bbgg.

Brown/Blue

b b

b

bb bb

b

bb bb

Green/Hazel

g g

G

Gg Gg

G

Gg Gg So the offspring (Student #1) is bbGg, which should result in hazel eyes.

However, the green/hazel gene has incomplete dominance. This means that the expressed phenotype can be anywhere from pure green to dark hazel depending on the genes given by the parents.

Student #2 – brown eyes Father – brown eyes Paternal Grandparents Mother – blue eyes Maternal Grandparents Grandfather – brown eyes Grandmother – brown eyes Grandfather – blue eyes Grandmother – hazel eyes

Punnett Square for Student #2

Student #2’s Mother has allele combination bbgg and Father has BBGG.

Brown/Blue

B B

b

Bb Bb

b

Bb Bb

Green/Hazel

G G

g

Gg Gg

g

Gg Gg So the offspring (Student #2) is BbGg, which results in brown eyes. The dominant phenotype here is brown eyes, as every possible combination results in brown eyes.

Punnett Square for Potential Offspring Student #1’s allele combination is bbgg, and Student #2’s allele combination is BbGg.

Here is the Punnett Square, and the various combinations follow:

Brown/Blue

B b

B

BB Bb

b

Bb bb

Green/Hazel

G g

g

Gg gg

g

Gg gg Student #1 is homozygous in their gene makeup. Both alleles for each genes are the same (bb and gg). Student #2 is heterozygous in their gene makeup. Student #2 posseses both alleles for each gene (Bb and Gg).

Punnett Square for Potential Offspring See the possible combinations of the two genes (brown/blue, green/hazel):

Brown/Blue

B b

Green/Hazel

G g

B

BB Bb

g

Gg gg

b

Bb bb

g

Gg gg Each brown/blue gene can be paired up with 4 different green/hazel genes. This is repeated with each brown/blue gene. Therefore there are 16 different gene pairs. These are listed on the next slide.

Possible Genotypes

 The 4 brown/blue genes we paired are BB, Bb, Bb, and bb. These were taken from the Punnett Square.

Brown/Blue Gene Possible Pairs with Green/Hazel

BB pair BBGg, BBGg, BBgg, BBgg Bb pair (first) BbGg, BbGg, Bbgg, Bbgg Bb pair (second) bb pair BbGg, BbGg, Bbgg, Bbgg bbGg, bbGg, bbgg, bbgg  Number of Genotypes = 16  BBGg = 2, BBgg = 2, BbGg = 4, Bbgg = 4, bbGg = 2, bbgg = 2

Genotype Probabilities

       Number of Genotypes = 16  BBGg = 2, BBgg = 2, BbGg = 4, Bbgg = 4, bbGg = 2, bbgg = 2 Probability of BBGg offspring = 2/16 * 100 = 12.5% Probability of BBgg offspring = Probability of BbGg offspring = Probability of Bbgg offspring = 2/16 * 100 = 12.5% 4/16 * 100 = 25% 4/16 * 100 = 25% Probability of bbGg offsrping = Probatility of bbgg offspring = Total 2/16 * 100 = 12.5% 2/16 * 100 = 12.5% 100%

Brown Phenotype Probability

There are 4 genotypes that produce a brown eyed offspring: • BBGg, BBgg, BbGg, Bbgg Since brown is dominant over all other colors the presence of a big B allele will automatically give the child brown eyes, regardless of the green/blue gene.

Adding the probabilities for each of the genotypes we get the total probability for the phenotype • 12.5% + 12.5% + 25% + 25% = 75% probability of having a brown eyed offspring

Hazel Phenotype Probability

For the green/hazel gene to be shown in a phenotype the brown/blue gene must be bb.

There is one genotype that will give you hazel eyes. Because the gene for green/hazel eyes has incomplete dominance you need a heterozygous genotype for green/hazel to have hazel eyes.

• bbGg Since there is only one genotype for hazel eyes, the probability for the phenotype is the same as the probability for the genotype.

• bbGg = 12.5% probability of having a hazel eyed offspring

Green Phenotype Probability

The green phenotype requires a genotype of bbGG. Since this genotype is not represented in our hypothetical offspring, the probability of green phenotype is 0%.

Blue Phenotype Probability

The only genotype that produces a blue phenotype is bbgg.

Because of this the probability of the genotype is the same as the probability of the phenotype.

12.5% probability child will have blue eyes.

Conclusion!

It is most probable that if Student #1 and Student #2 were to create an offspring, that offspring would have the phenotype of brown eyes. It is impossible for their offspring to have green eyes.