Transcript Experimental Probes Soft Materials, Polymers, Experimental Biophysics Na

Experimental Probes
Soft Materials, Polymers,
Experimental Biophysics
Rama Bansil
Shyamsunder Erramilli
Kenneth Rothschild
Nanostructures and Materials
Michael El-Batanouny
Bennett Goldberg
Karl Ludwig
Raj Mohanty
William Skocpol
Kevin Smith
Intensity (counts
From one to many
y (micron)
Condensed
Theory of formation,
growth dynamics
Gene Stanley
Sid Redner
Bill Klein
From atoms to
clusters to
nanostructures to
polymers to life
Collective behavior
Interdisciplinary Science
-- Photonics, Engineering,
Biology, Economics,
BioMedical
BOSTON UNIVERSITY PHYSICS DEPARTMENT
Matter
Many-body Theory
Anders Sandvik
Claudio Chamon
Antonio Castro Neto
CONDENSED MATTER EXPERIMENT
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Rama Bansil
Michael El-Batanouny
Bennett Goldberg
Karl Ludwig
Raj Mohanty
William Skocpol
Kevin Smith
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Other Physics faculty with
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He-Scattering Facility – Michael El-Batanouny
DOE
BOSTON UNIVERSITY PHYSICS DEPARTMENT
Magnetic Domain Formation
S z = ± 3/2
) = 29 meV
S z = ± 1/2
TN bu lk
BOSTON UNIVERSITY PHYSICS DEPARTMENT
T N s urface
Spectroscopic Measurements of
Electronic Structure in Novel Materials
• NSF
Professor Kevin Smith
• ARO
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The BU
Novel
Materials
Group:
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• DOE
Professor Cormac McGuinness
Dr. Per-Anders Glans
James Downes
Dongfeng Fu
Tim Learmonth
Paul Sheridan
Lindsey McCaslin
Experiments are performed at:
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The National Synchrotron Light Source, Brookhaven National Lab, New York
The Advanced Light Source, Lawrence Berkeley National Lab, California
The MAXLAB light source, Lund, Sweden
The HASYLAB light source, Hamburg, Germany
BOSTON UNIVERSITY PHYSICS DEPARTMENT
OUTLINE
Our group deals with two broad topics:
 The application of established spectroscopies to study
electronic structure in complex solids
 The development of new spectroscopies suitable for
complex materials
Two primary spectroscopies are used:
 Angle Resolved Photoemission (ARP)
Measures surface and bulk band structure
Measures many body effects in correlated solids
 Soft X-Ray Emission (SXE) / Resonant Inelastic X-Ray
Scattering (RIXS)
Measures bulk electron density of states, resolved by element,
and resolved by orbital angular momentum component
At resonance, measures low energy excitations in an inelastic
scattering mode.
Three systems are being studied:
 Correlated and Low Dimensional Solids
 Organic Superconductors and Metals
 Wide Band Gap Semiconductors
BOSTON UNIVERSITY PHYSICS DEPARTMENT
EXAMPLES
Three examples will be presented:
1. Many body interactions in the layered twodimensional conductor TaSe2
The next figure shows a map of the photoemission intensity
from TaSe2
From this data we can extract quantitative measurements of
the many-body interactions: electron-impurity scattering,
electron-charge density wave scattering
The many-body interactions are described by the
quasiparticle self-energy, as shown in the subsequent
figure.
Published in Physical Review Letters, 85, 4759 (2000)
2. Band gap evolution in nitride alloys.
3. Elementally resolved band structure in organic
superconductors
BOSTON UNIVERSITY PHYSICS DEPARTMENT
ARP from TaSe2
a)
b)
0.0

 (eV)
-0.1
-0.2
-1
M
kF-k (Å ):
K
0
0.065
0.082
0.143
G
SK
SC
-0.3
-0.10
-0.05
0.00
-1
k-kF (Å )
0.05
Intensity
T = 34 K
BOSTON UNIVERSITY PHYSICS DEPARTMENT
Real and Imaginary parts of the self energy
in TaSe2 as a function of temperature
50
Im
80
40
30
34 K
34 K edc
76 K
76 K edc
111 K
111 K edc
40
20
20
Re
10
0
0
-250
-200
-150
-100
 (meV)
BOSTON UNIVERSITY PHYSICS DEPARTMENT
-50
0
Re (meV)
-Im (meV)
60
EXAMPLES
Three examples will be presented:
1. Many body interactions in the layered twodimensional conductor TaSe2
2. Band gap evolution in nitride alloys.
The next figure shows the elementally resolved valence
band electronic structure of the AlxGa 1-xN alloy system as
measured using high resolution soft x-ray emission
spectroscopy.
The linear evolution of the band gap is easily observed
Only three instruments in the U.S. are capable of making
these measurements.
AlGaN data published in Physical Review B, 58, 1928
(1998), our InGaN experiments have just been accepted to
PRB
3. Elementally resolved band structure in organic
superconductors
BOSTON UNIVERSITY PHYSICS DEPARTMENT
N 2p Partial Density of States in Al xGa1-xN
X
0
0.1
0.25
0.5
0.7
1.0
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-6
-4
-2
0
2
Binding Energy (eV) relative to AlN VBM
BOSTON UNIVERSITY PHYSICS DEPARTMENT
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EXAMPLES
Three examples will be presented:
1. Many body interactions in the layered twodimensional conductor TaSe2
2. Band gap evolution in nitride alloys.
3. Elementally resolved band structure in organic
superconductors
The next figure shows the elementally resolved valence band
electronic structure in the organic superconductor known as
-ET2Cu[N(CN)2]Br
Measurement was made using soft x-ray emission
spectroscopy
The spectroscopy allowed us to extract all the important
contributions to the occupied electronic structure in this
complex solid.
Published in J. Solid State Chemistry 143, 1 (1999).
BOSTON UNIVERSITY PHYSICS DEPARTMENT
C 2p SXE as a Function of Excitation Energy for -ET2Cu[N(CN)2]Br
Excitation
energy
hexec (eV)
310.0
298.0
291.8
289.6
289.0
288.0
265
270
275
280
285
290
Photon Energy (eV)
BOSTON UNIVERSITY PHYSICS DEPARTMENT
295
300
Karl Ludwig X-ray Group –
Real-Time X-ray Studies of Materials Processes
X-Ray Diffraction
Resistance
- Phase Formation
- Electrical Characterization
Light Scattering
- Surface Roughness
Lock-in #1
Laser
1013 /sec E = 6.9 keV
Focusing
X20C
Synchrotron
Mirror
Lock-in #2
Laser
Multilayer
Position
Monochromator
Sensitive
Detector
Linear
NSLS
Sample
•14° range in 2
•30ms time resolution
Annealing
Chamber
Beamline
Control
Analysis
Workstation
Experiment
Measurement
and Control
Electronics
Control
LabVIEW
BOSTON UNIVERSITY PHYSICS DEPARTMENT
X-ray Detector
• Growth of C54 TiSi2 Phase Used in Semiconductor Industry
(collaboration with IBM Research)
27 nm Ti
BOSTON UNIVERSITY PHYSICS DEPARTMENT
• Development of Surface Nanostructures During Ion Bombardment
(collaboration with Naval Research Lab)
8000
150 eV
6000
1210 sec
4000
1050 sec
735 sec
2000
0 sec
0
0
0.1
0.2
0.3
0.4
qx [nm-1]
0.5
0.6
Evolution of x-ray scattering during ion
bombardment showing formation of surface nanostructures
AFM image after ion
bombardment showing
formation of “nanodots”
•Growth of III-V Nitride Semiconductors by Molecular Beam Epitaxy
(collaboration with Moustakas – Electrical Engineering)
BOSTON UNIVERSITY PHYSICS DEPARTMENT
An In-situ UHV Materials Processing Facility
at National Synchrotron Light Source
NSF, DOE
Real-time X-ray Studies of:
• III-nitride thin film growth
by MBE
• Surface evolution during
sputter erosion and plasma
exposure
• Ultra-thin (< 10 nm)
silicide film formation –
Co-Si, Ni-Si
BOSTON UNIVERSITY PHYSICS DEPARTMENT
Biological and Synthetic Nanoscale
Structures formed by Macromolecules
Rama Bansil – NSF
• Microscopy
• Light Scattering
• Small-angle X-ray
Scattering
• Small-angle
Neutron Scattering
BOSTON UNIVERSITY PHYSICS DEPARTMENT
Bennett Goldberg – Nano-optics of Quantum Structures
 Simultaneous electronic and
optical quantum confinement
 Manipulate the electronic
excitations with optical fields,
D lifetime, spin, coupling
 Quantum computing,
nanoscale electronics,
photonics
BOSTON UNIVERSITY PHYSICS DEPARTMENT
Low-Temperature Near-field Scanning Optical Microscopy
Self Assembled Quantum Dots:

Small (10-20nm) - Confinement ~ Coulomb energy
 Virtually defect free - very high quantum efficiency
 Homogenous size distribution
 Self - assembly, Straski-Krastanov growth
100x
Emission Intensity (a.u.)
Atomic-like emission due to 3D
quantum confinement
Ensemble of ~30 self-assembled
quantum dots measured by ~100nm
near-field tip at 4K
homogeneous linewidth < 0.1 meV
1850
1900
1950
Energy (meV)
BOSTON UNIVERSITY PHYSICS DEPARTMENT
2000
Spatial spectroscopy scans
 Build 3D data set: x - y - l, -- then take slices at specific l
l -- scan through emission line of dot in center
 Imaging a single quantum dot
1888.34
1888.41
1888.48
Intensity (counts
doughnut shape due to tip shadowing
1.0
y 1889.68
(micron)
meV
y (micron)
0.8
1888.55
1888.62
1888.69
1888.76
1888.83
1888.90
0.6
0.4
0.2
size of tip
0.0
0.0 0.2 0.4 0.6 0.8 1.0
x (micron)
streaks due to spectra diffusion
BOSTON UNIVERSITY PHYSICS DEPARTMENT
• Quantum Information
Electronic
Systems
• Quantum-Classical Transition
• Fundamental properties of
Metals, Insulators, Superconductors
PHYSICS WITH NANOSTRUCTURES
Mechanical
Systems
• Quantum “Mechanical” Oscillator
• Dissipation and Quantum Friction
• Fundamental Force Measurements
with Micromechanical Structures
• Quantum regime of heat flow
Laboratory for Nanoscale Research, Prof. Raj Mohanty + Prof. William Skocpol
BOSTON UNIVERSITY PHYSICS DEPARTMENT
Nanoscale Electronic
Structures
Nanoscale Mechanical
Structures
Advanced E-beam lithography & surface micromachining
Quantum Decoherence
Coherent electrons
over 25 mm and 80 ns
Schrodinger’s Kitten
(8 mm loop)
Persistent current
from a single electron
Berry Phase
Spin rotation of single
Electron (by p/6) about
another localized spin
BOSTON UNIVERSITY PHYSICS DEPARTMENT
Quantum Dissipation
Energy relaxation in
Micro-electromechanical
Systems (MEMS)
Force Detection
Nanoscale Antenna
Mechanical sensor for
ultrasmall force
detection
(DNA, Gravity,tunneling)
a single electron
Quantum Friction
Mechanical (friction)
force, due to the
tunneling of
a handful of atoms
Problems being addressed in the Lab
Electronic
Structures
Mechanical
Structures
• How to fabricate, control
& manipulate a quantum bit
to create coherence and
(EPR) entanglement
•
What determines energy loss
(quantum dissipation) in
Nano- or Micro-Electro
Mechanical Systems
• How to control & reverse
quantum decoherence in
any quantum system
•
Is the Newton’s inverse-square
law of gravity valid in micron
distance scales
(Do extra dimensions exist)
•
Does heat flow in nanoscale
structures occur according to
quantum mechanics
• How do the nanoscale
high-Tc superconductors
behave
Laboratory for Nanoscale Research, Prof. Raj Mohanty
BOSTON UNIVERSITY PHYSICS DEPARTMENT
Physics Research in Affiliated Areas
Quantum Optics, Biomedical Optics, Ultramicroscopy,
Device and Materials Physics, Nanoscience, Nanobiotech
Ted Moustakas ECE
Selim Ünlü ECE
Alexander Sergienko ECE
Bahaa Saleh ECE
Mal Teich ECE
Irving Bigio BME
Evan Evans BME
Kamil Ekinci AME
Todd Murray, AME
Tejal Desai, BME
BOSTON UNIVERSITY PHYSICS DEPARTMENT
QUANTUM IMAGING LABORATORY
at Boston University
CO-DIRECTORS:
B. E. A. Saleh, A. V. Sergienko, M. C. Teich
http://www.bu.edu/qil
Quantum Information and Communication, Quantum Networking: multiparty secure quantum key
distribution (quantum cryptography).
(In cooperation with Tom Toffoli and Lev Levitin at BU).
Quantum Imaging (Spatial Entanglement at Work): designing imaging
configurations for unconventional practical applications.
Quantum Ellipsometry: characterization of surface properties of semiconductors,
and materials used in optoelectronics.
Quantum Optical Tomography: (of real objects) do not confuse with tomography
of quantum states.
The feasibility of cryptography, metrology, and imaging has been demonstrated
experimentally in our laboratory and experiments demonstrating ellipsometry,
microscopy, tomography, and holography are underway.
Parametric Down Conversion - source of entangled states
Phase Matching TYPE I
QuickTime™ and a
Sorenson Video decompressor
are needed to see this picture.
-Photons 1 and 2 have
the same polarization and
traverse the same direction
BOSTON UNIVERSITY PHYSICS DEPARTMENT
Phase Matching TYPE II
QuickTime™ and a
Sorenson Video decompressor
are needed to see this picture.
-Photons 1 and 2 have
orthogonal polarizations
and travel different directions
Quantum Ellipsometry
A2
Coincidence
Detection
NLC
LASER
LIGHT
A1
SAMPLE (y, D)
-Makes use of polarization-entangled photon pairs generated from type-II
spontaneous parametric down conversion.
-Interferometric scheme in conjunction with using two-photon source
provides a “natural” self-referencing.
-A reference sample need not be used for ellipsometric measurements.
BOSTON UNIVERSITY PHYSICS DEPARTMENT
Proposed Applications
Quantum Information and Communication, Quantum Networking:
multiparty secure quantum key distribution (quantum cryptography).
(In cooperation with Tom Toffoli and Lev Levitin at BU).
Quantum Imaging (Spatial Entanglement at Work): designing imaging
configurations for unconventional practical applications.
Quantum Ellipsometry: characterization of surface properties of semiconductors,
and materials used in optoelectronics.
Quantum Optical Tomography: (of real objects) do not confuse with tomography
of quantum states.
The feasibility of cryptography, metrology, and imaging has been demonstrated
experimentally in our laboratory and experiments demonstrating ellipsometry,
microscopy, tomography, and holography are underway.
BOSTON UNIVERSITY PHYSICS DEPARTMENT
Near field and Picosecond Spectroscopy
•
•
•
•
•
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•
•
M. Selim Ünlü, B. B. Goldberg
Anna Swan
Ultramicroscopy
DARPA, NSF, ONR, ARO, NIH
Material Characterization
GaN - time-resolved spectroscopy
Scanning probe microscopy
• NSOM
Waveguides, biosensing
Thermal Imaging
Photodetectors
HYPX MRI
BOSTON UNIVERSITY PHYSICS DEPARTMENT
NANO
OPTICS
Carbon Nano-tubes
Imaging of PBG, Waveguide Devices and Lasers
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High spatial resolution subsurface microscopy
Quantum Dot Spectroscopy
BOSTON UNIVERSITY PHYSICS DEPARTMENT
Goldberg & Ünlü
NAIL: Numerical Aperture Increasing Lens
100X objective
Conventional
State-of-the-art
BOSTON UNIVERSITY PHYSICS DEPARTMENT
10 mm
10X w/ NAIL
Boston Univ.
Comparison of Confocal to Tip-Enhanced in Raman
Microscopy of Carbon nanotubes
BOSTON UNIVERSITY PHYSICS DEPARTMENT
Raman scattering in a nutshell
Lattice vibrations
lscattered
Stokes
Anti-Stokes
llaser
-300
Energy units for optical spectroscopy
1/l (cm-1)
E(eV )  h  ck  hc  1240
l l(nm)
1/l = wavenumber
500 nm = 20 000 cm-1
300 cm-1 = 37.2 meV
BOSTON UNIVERSITY PHYSICS DEPARTMENT
-200
-100
0
100
200
300
-1
Raman shift (cm )
Energy and momentum
conservation:
     

L
S
phonon






KL  KS  qphonon
Resonant Raman Scattering


Laser light in to illuminate at most
one tube at a time
Only tubes in resonance with light
will interact & start to vibrate (or give
up vibration energy to light)
Signal=laser  vibration energy from
resonant tubes
RBM
BOSTON UNIVERSITY PHYSICS DEPARTMENT
G
Measures the
properties of
an individual
tube
SWNT on a Substrate with Grid
1mm
laser spot size
AFM image
RBM=185cm-1 dt=1.34nm
Lithography: Steve Cronin, Harvard
BOSTON UNIVERSITY PHYSICS DEPARTMENT
SURFACE ENHANCED VIBRATIONAL SPECTROSCOPY
AND MICROSCOPY
o - N
o
N
Phys.Rev.Lett. 90, 95503 (2003)
BOSTON UNIVERSITY PHYSICS DEPARTMENT
Carbon nanotubes: - well defined topography
- large sRaman
- resonance enhancement
NEAR-FIELD RAMAN IMAGING OF CARBON NANOTUBES
topography
BOSTON UNIVERSITY PHYSICS DEPARTMENT
Raman scattering
line-scan
Self Interference of fluorescent light
Self interference between directly
emitted and reflected light
interferes constructively or
destructively depending on
wavelength and height over mirror.
spacer
SiO2
Si
mirror
BOSTON UNIVERSITY PHYSICS DEPARTMENT
The Si substrate serves as a
mirror and the transparent SiO2
as a spacer.
Fluorescein on surface and on top of Streptavidin
Demonstration of better than 5 nm vertical resolution
Shift between
Fluorescein on Streptavidin (red)
and Fluorescein (black)
Shift in curves indicates
6.5 2 nm height difference
-6 nm
+6nm
10 mm
17000 18000 19000 20000
~5 nm
False color map:
Color == nanometer height
BOSTON UNIVERSITY PHYSICS DEPARTMENT
Wide Bandgap Semiconductors
Laboratory
Theodore D. Moustakas
In this laboratory we address materials and device physics issues
of the wide bandgap semiconductors InN, GaN, AlN and their alloys
and heterostructures. Current projects are related to making visible
and ultraviolet LED and laser structures, solar-blind, UV
photodetectors, electronic devices (diodes, transistors, thyristors)
and MEMS sensors.
The materials and devices are grown by molecular beam epitaxy
(MBE), vapor phase epitaxy (VPE) and gas cluster ion-beam
deposition (GCIB).
Wide Bandgap
Semiconductors Lab
BOSTON UNIVERSITY PHYSICS DEPARTMENT
BOSTON
UNIVERSITY
Lattice Constant (Å)
Bandgap-lattice constant
InN
3.50
3.25
GaN
AlN
3.00
visible
ultraviolet
2.75
2.0
3.0
4.0
5.0
6.0
7.0
Bandgap Energy (eV)
Wide Bandgap
Semiconductors Lab
BOSTON UNIVERSITY PHYSICS DEPARTMENT
BOSTON
UNIVERSITY
Schematic of the ECR-MBE system
Rotating heated
wafer holder
Compact ECR
source
N2 purifier
RHEED
gun
Beam flux
monitor
Transfer
rod
N2
Shutter
Group III:
Buffer
chamber
Ga, Al, In
Substrate
Dopants:
Si, Mg
Effusion
cell
Wide Bandgap
Semiconductors
Lab DEPARTMENT
BOSTON
UNIVERSITY PHYSICS
Q uadrupole
mass spectrometer
RHEED
screen
BOSTON
UNIVERSITY
Schematic of the vertical cavity laser
Ag metallic mirror
25.5 periods
InGaN/GaN MQWs
25.5 periods
AlN/GaN DBR
GaN
AlN
Sapphire
Wide Bandgap
Semiconductors Lab
BOSTON UNIVERSITY PHYSICS DEPARTMENT
BOSTON
UNIVERSITY
Laboratory for Nanometer Scale
Mechanical Engineering
Kamil L. Ekinci
[email protected]
BOSTON UNIVERSITY PHYSICS DEPARTMENT
Nanomechanics at BU
Focus areas:
1. Surface analysis and engineering of nanostructures at the atomic scale
2. Nanoelectromechanical Systems (NEMS) sensors and signal processing components
Experimental set up:
UHV Surface analysis
chamber
High frequency NEMS
Silicon atoms on the
surface of a device
BOSTON UNIVERSITY PHYSICS DEPARTMENT
NEMS to measure single molecules
Nanomechanical system moves nanometers at ultra high
frequency => Sensitive to tiny amounts of material
magnetomotive actuation and transduction
single molecule detectors
•single molecule chemical sensors
•mass spectrometry
BOSTON UNIVERSITY PHYSICS DEPARTMENT
Kamil Ekinci
What are nanomachines good for?
Unprecedented sensitivities
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Ultrafast electromechanical devices
Sensors sensitive to single molecules
Capable of detecting tiny forces
…
Interesting Physics
• Mesoscopic and molecular limit to mechanics
• No longer at the classical limit,
quantum mechanics take over.
• No longer at the thermodynamic limit,
atomistic processes are important
BOSTON UNIVERSITY PHYSICS DEPARTMENT
AME Laser Acoustics Lab: Photoacoustic and
Photothermal (PA/PT) Characterization at the
Nanoscale
PA/PT techniques well suited for materials
characterization at the macro/micro scales but
spatial resolution limited by diffraction
Laser interaction with materials: physical processes
used in photoacoustic and photothermal microscopy.
Evaluation of thermomechanical properties of nanoscale
systems through photoacoustic and photothermal
microscopy requires higher resolution: Nearfield Optical
Techniques
High resolution photoacoustic and photothermal
microscope in the Laser Acoustics Lab.
Research part of NIRT effort
BOSTON UNIVERSITY PHYSICS DEPARTMENT
Photothermal and Photoacoustic Characterization of Nanoscale Systems
Plasmon resonance in nanoparticles may help
us to localize the excitation laser energy
PL
y
NA
EL
x
l
EAM
PD
EL
L
(a)
NEMS
(b)
We are currently evaluating the use of PA/PT
to measure the thermal and mechanical
response of nanoelectromechanical systems
(NEMS)
BOSTON UNIVERSITY PHYSICS DEPARTMENT
Nanomechanical resonators fabricated at BU (Ekinci)
Supported through NSF NER
Nanotechnology
Research @ BOSTON
UNIVERSITY
Bennett Goldberg
Electrical and Computer Engineering
Physics
[email protected]
[email protected]
BOSTON UNIVERSITY PHYSICS DEPARTMENT
Material Synthesis & Device Fabrication
Nanomachining
Advanced E-beam lithography & surface
micromachining (Mohanty, Physics)
(Ekinci, Mech.ENG)
BioMEMS/NEMS (Desai
and Tien, BME)
•Optoelectronics Processing Facility
•Lightwave Technology Laboratory
III-V Nitride MBE
(Moustakas, ECE)
BOSTON UNIVERSITY PHYSICS DEPARTMENT
Ekinci, Moustakas, Mohanty
Applications in Biology and
Biomedical Engineering :
Nano-Bio-Technology
5 mm Nanoporous Silicon (pSi)
Particles
Self Assembly of Scaffolds
•High Resolution Biological Imaging
Interdisciplinary Research Teams
Volume (Particle) = 68 fL
Volume (RBC) = 76 – 100 fL
BOSTON UNIVERSITY PHYSICS DEPARTMENT
Desai & Tien
Why Therapeutic Nanotechnology?
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Significant unmet medical needs
Nanoscale features mimic biological world
Unprecedented control over features (surface
chemistry, topography)
Targeting and localization
Self-regulation (sensing & transduction)
Novel Materials
MULTI-FUNCTIONALITY
BOSTON UNIVERSITY PHYSICS DEPARTMENT
Fiction: Nano-robots or the Fantastic Voyage
BOSTON UNIVERSITY PHYSICS DEPARTMENT
Fact: Non-Invasive Delivery
of Peptides and Proteins
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
Lectin coating
•
Nano-reservoirs
•
•
•
BOSTON UNIVERSITY PHYSICS DEPARTMENT
adheres to intestinal mucosa
Filled with EPO (
) and
enhancer (
) [lyophilized]
Drug released close to
intestinal cells
Locally high concentrations to
enhance paracellular
transport
Future: Integrated Drug Delivery Nanosystems
Biosensors
Tumor Targeting
Molecule, Cell
Reservoir
Sensor Interface
Encapsulation
Packaging
Power
Supply
Nanopores
Antenna
Actuator
Control Electronics
Fantastic voyage?
BOSTON UNIVERSITY PHYSICS DEPARTMENT
Interconnect
Center for Nanotechnology Integration
horizontal integration across disparate scientific disciplines
CNI combines
vertical integration from basic science through
transitional technologies to market opportunities
Nanoscience and nanotechnology toward applications in
human physiology
Tissue Engineering
Electronics/Photonics
NEMS & MEMS
Characterization
Materials Science
Nanofabrication
Basic Science
Medical Applications
Smart Devices
Manufacturing
Biomimetic Materials
Working from basic science through application engineering to device delivery
BOSTON UNIVERSITY PHYSICS DEPARTMENT
Integrating scientists, engineers,
medical doctors, entrepreneurs, and VC
New companies
Understanding
human Physiology
NANOTECHNOLOGY
Physical Sciences
Electronics/Optics/IT
Need Identified
Enrico Belloti
Thomas Bifano
Kamil Ekinci
Shymasunder Erramilli
Bennett Goldberg
Raj Mohanty
Ted Morse
Ted Moustakas
Bahaa Saleh
Anna Swan
Selim Ünlü
Energy
Srikanth Gopalan
Uday Pal
Vinod Sarin
Life Sciences
Tissue Engineering
Characterization
Rama Bansil
Bennett Goldberg
Todd Murray
Anna Swan
Selim Ünlü
Materials Science
Kevin Smith
Bennett Goldberg
Karl Ludwig
M. Selim Ünlü
Ted Moustakas
Biomimetic Materials
Tejal Desai
Russell Giordano
Catherine Klapperich
Joe Tien
Joyce Wong
Xin Zhang
Manufacturing
Smart Devices
Thomas Bifano
Tejal Desai
Kamil Ekinci
Raj Mohanty
Andre Sharon
Joe Tien
Xin Zhang
Thomas Bifano
Irving Bigio
Tejal Desai
Kamil Ekinci
Shymasunder Erramilli
Evan Evans
Maxim Frank-Kamenetski
Rosina Georgiadis
Bennett Goldberg
Raj Mohanty
Ted Morse
Biology
Todd Murray
James Deshler
Anna Swan
Selim Ünlü
Joyce Wong
Xin Zhang
Homeland Security
Bennett Goldberg
Shymasunder Erramilli
Raj Mohanty
Ranjith Premisiri
Selim Ünlü
BOSTON UNIVERSITY PHYSICS DEPARTMENT
Tejal Desai
Evan Evans
Russell Giordano
Catherine Klapperich
Joe Tien
Joyce Wong
Genomics & Proteomics
Charles Cantor
Jim Collins
Michael Christman
Charles Delisi
Jim Deshler
Shymasunder Erramilli
Maxim Frank-Kamenetski
Rosina Georgiadis
Catherine Klapperich
Cassandra Smith
Zhiping Weng
Core Nanoscience efforts at Boston University
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Nano-optics in materials science
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Nanoscale Interdisciplinary Research Team developing optical techniques for at length scales of λ/10. NSF
MURI with U of R
Nano-optics in subcellular bioimaging and medicine
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Using new techniques in interference microscopy to image fluorophores in vivo with nanometer resolution.
NIH+NSF
Nano-electromechanical systems
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Nanosensor arrays for molecular detection using UHF cantelevers. NEMS for microengines, active mirrors, rapid
and variable genomic and protein array fabrication
Nano-electronics
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Nanowires, dots, and devices for coherent transport for secure communications and quantum computing
Whitaker Laboratory for Micro and Nano Biosystems
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Nanotherapeutics: Targeted drug delivery, nanoporous membranes, smart nanoparticles
Cellular scaffolding, polymer tethers
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3D self assembly
Nanomechanics of biosystems: Individual chemical bonds
Dip-pen nanolithography, polymers
Infrared microscopy to 100nm, femtogram spectroscopy and breast cancer screening using a single
strand of hair
Biosensing and homeland security
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Surface Plasmon Resonance, Array-based, multichannel sensors
Ring resonators and fiber-based systems
Proteomics and genomics
BOSTON UNIVERSITY PHYSICS DEPARTMENT
Education in interdisciplinary Nanoscience
IGERT in Micro- and Nano-Biosystems
Biology
Physics
Internships at
industrial
research labs,
national labs,
and
international
centers of
excellence.
Engineering:
BME, AME,
ECE, MFG
Health
Science
Chemistry
Core courses in departmental
discipline
Core interdisciplinary courses in Micro/Nanoscience
•Physical Phenomena
•Structures and Fabrication
•Measurement and Analysis
Augmented by
journal clubs,
lab rotations,
and bioethics,
societal
impact, and
tech transfer,
seminars
Existing Advanced courses in Micro/Nanoscience
Physics: NEMS
for single
molecule
measurements
Engineering
Nano-photonic
devices for
DNA sensing
BOSTON UNIVERSITY PHYSICS DEPARTMENT
Biology:
Cells on
biomimetic
structures
Dental:
Nanocomposites
for tooth
replacement
Chemistry:
Nanostructured
arrays for SPR
of DNA