List of publications

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Transcript List of publications

List of publications
First and shared first author publications
Montalbán-López,M.*, van Heel,A.J.*, and Kuipers,O.P. Employing the promiscuity of lantibiotic
biosynthetic machineries to produce novel antimicrobials. Submitted.
van Heel,A.J., Kloosterman,T., Montalbán-López,M., Jingjing,D., Plat,A., Hendriks,D., Baptiste,B.,
Moll,G.N. and Kuipers,O.P. Discovery, production and modification of 5 novel lantibiotics using the
promiscuous nisin modification machinery. Submitted.
van Heel,A.J.*, Montalbán-López,M.*, and Kuipers,O.P. Genome-guided discovery of pumilarin, a novel
head-to-tail cyclized antimicrobial peptide produced by Bacillus pumilus. In revision.
van Heel,A.J.*, Mu,D.*, Montalbán-López,M., Hendriks,D. and Kuipers,O.P. (2013) Designing and
producing modified, new-to-nature peptides with antimicrobial activity by use of a combination of
various lantibiotic modification enzymes. ACS Synth. Biol., 2, 397–404.
van Heel,A.J.*, de Jong,A.*, Montalbán-López,M., Kok,J. and Kuipers,O.P. (2013) BAGEL3: automated
identification of genes encoding bacteriocins and (non-) bactericidal posttranslationally modified
peptides. Nucleic Acids Res., 41, W448–W453.
van Heel,A.J.*, Montalban-Lopez,M.* and Kuipers,O.P. (2011) Evaluating the feasibility of lantibiotics
as an alternative therapy against bacterial infections in humans. Expert Opin. Drug Metab. Toxicol., 7,
675–680.
de Jong,A.*, van Heel,A.J.*, Kok,J. and Kuipers,O.P. (2010) BAGEL2: mining for bacteriocins in genomic
data. Nucleic Acids Res., 38, W647–51.
*= Both authors contributed equally
Other publications
Zhou,L., Shao,J., Li,Q., van Heel,A.J., de Vries,M.P., Broos,J. and Kuipers,O.P. (2016) Incorporation of tryptophan
analogues into the lantibiotic nisin. Amino Acids, 10.1007/s00726-016-2186-3.
Zhou,L., van Heel,A.J., Montalban-Lopez,M. and Kuipers,O.P. (2016) Potentiating the activity of nisin against
Escherichia coli. Front. Cell Dev. Biol., 4.
Back,A., Borges,F., Mangavel,C., Paris,C., Rondags,E., Kapel,R., Aymes,A., Rogniaux,H., Pavlović,M., van Heel,A.J.,
et al. (2015) Recombinant pediocin in Lactococcus lactis: increased production by propeptide fusion and improved
potency by co-production with PedC. Microb. Biotechnol., 10.1111/1751-7915.12285.
Zhou,L., van Heel,A.J. and Kuipers,O.P. (2015) The length of a lantibiotic hinge region has profound influence on
antimicrobial activity and host specificity. Front. Microbiol., 6, 11.
de Jong,A., van Heel,A.J., Montalban-Lopez,M., Krawczyk,A.O., Berendsen,E.M., Wells-Bennik,M. and Kuipers,O.P.
(2015) Draft Genome Sequences of Five Spore-Forming Food Isolates of Bacillus pumilus. Genome Announc., 3.
Khusainov,R., van Heel,A.J., Lubelski,J., Moll,G.N. and Kuipers,O.P. (2015) Identification of essential amino acid
residues in the nisin dehydratase NisB. Front. Microbiol., 6, 102.
Daszczuk,A., Dessalegne,Y., Drenth,I., Hendriks,E., Jo,E., van Lente,T., Oldebesten,A., Parrish,J., Poljakova,W.,
Purwanto,A.A., et al. (2014) Bacillus subtilis biosensor engineered to assess meat spoilage. ACS Synth. Biol., 3,
999–1002.
Wood,K., Gallat,F.-X., Otten,R., van Heel,A.J., Lethier,M., van Eijck,L., Moulin,M., Haertlein,M., Weik,M. and
Mulder,F.A.A. (2013) Protein Surface and Core Dynamics Show Concerted Hydration-Dependent Activation. Angew.
Chem. Int. Ed Engl., 125, 693–696.
Montalbán-López,M., Zhou,L., Buivydas,A., van Heel,A.J. and Kuipers,O.P. (2012) Increasing the success rate of
lantibiotic drug discovery by Synthetic Biology. Expert Opin. Drug Discov., 7, 695–709.
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