Transcript Von Delft Part 2 - Treatment Action Group

Why are new drugs and cheaper,
more user friendly regimes needed?
"Tuberculosis, whether caused by drug-susceptible or drugresistant strains, rarely made even medical headlines, in part
because its importance as a cause of death continued to decline
in areas in which headlines are written.”
Keshavjee and Farmer, NEJM, 2012*
And what TB
crisis?
* Tuberculosis, Drug Resistance, and the History of Modern Medicine. Salmaan Keshavjee and Paul Farmer. N Engl J Med. 2012 Sep 6;367(10):931-6.
Cost-ineffective?
“…selective primary health care and ‘cost-effectiveness’ have shaped
an anemic response to the ongoing global pandemic.”*
*Tuberculosis, Drug Resistance, and the History of Modern Medicine. Salmaan Keshavjee and Paul Farmer. N Engl J Med. 2012 Sep 6;367(10):931-6.
Slide courtesy: Prof Keertan Dheda
SA : MDR-TB already >55% of TB budget!
Financing the scale-up of MDR-TB prevention and Treatment. Katherine Floyd, Stop TB, WHO. Ministerial meeting. Beijing, China, 2009
http://www.who.int/tb_beijingmeeting/media/press_pack/presentations/day2_presentation3.pdf
The perception among the majority is that we are not at risk of being infected by TB.
This assumption is deeply flawed.
Dr Madhukar Pai, India Tribune, 29 October 2012
The RNTCP needs to think beyond treatment of drug-resistant TB, and focus on
preventing a major epidemic. In the case of drug-resistant TB, an ounce of prevention
is definitely better than a pound of cure
http://www.tribuneindia.com/2012/20121029/edit.htm#6
Care for the carer
• ±1/100: number of South Africans diagnosed with TB
last year (WHO, 2012).
• 3x: increased rate of TB among Health Care Workers
globally (Baussano, 2011).
• 6.3%: confirmed drug-resistance among occupational
TB cases at Tygerberg Hospital (Data: 2008-2011).
• 5.56x higher incidence rate of MDR- and XDR
(O’Donnell, 2010)
• Means 3/100 HCW’s could be diagnosed with TB every
year
• At least 1/16 could have MDR-TB or worse
Lucky and thankful…
• Dalene got her life back, she can still hear, and
can even practice as a clinician again…what
next?
TB PROOF
Start at the beginning:
nd
2
Year Medical Students
Anyone can get TB
Nobel peace prize TB survivors
“UBUNTU” – I am because we are
We are all in this together!
http://www.health24.com/tools/Slideshows/1891-4704-4775,61850.asp
HOPE: Life after TB
SA record: 114m in one breath!
Physicians:
•
Paul Willcox
•
Andreas Diacon
•
Simon Schaaf
•
Tony Biebuyck
•
Jantjie Taljaard
•
Keertan Dheda
Pharmacology
•
Gary Maartens
•
Elsimé Kift
•
Jeannine Du Bois
Supportive
•
Justus Apffelstaedt - Surgery
•
Mou Manie - Rheumatology
•
Anton Doubell - Cardiology
•
Mark Abelson – Cardiology
•
Prof Loock – Ear, nose and throat
Radiology
•
Sucari Vlok
•
Arthur Maydall
•
Jan Lotz
Occupational Health/TBH
•
Jack Meintjies
•
Sr Samuels
•
Sr Arendse
•
Matodzi Mukosi - super
•
Elmarie Malek
•
Mariana Kruger
SAMA - Daniel Madiba
Thank you!
CBTBR/Genetics:
•
Gerhard Walzl
•
Belinda Kriel
•
Daleen Kriel
•
Rob Warren
•
Tommie Victor
•
Soraya Bardien-Kruger
•
Lizma Streicher
Tibotec/Janssen:
•
David McNeeley
•
Gilles van Baar
NHLS
•
Mariza Hoffman
•
Haematology and Microbiology
Technologists
Audiology:
•
Rene Visagie
•
Sharon Pithey
•
Tygerberg Audiologists
CAPRISA
•
Nesri Padayatchi
•
Kogieleum Naidoo
TB PROOF
•
Angela Dramowski
•
Bart Willems
•
Heena Narotam
•
Helene-Mari van der Westhuizen
•
Koot Kotze
Treatment Action Group
“The momentum to break this disease is in real danger. We are now at a
crossroads between TB elimination within our lifetime, and millions
more TB deaths.”
Dr Mario Raviglione; Director of the WHO Stop TB Department;
17 October 2012
Questions?