Transcript Non-Sporeforming Anaerobes Non-Sporeforming Anaerobes Stains gram-variable or gram-negative, but not a gram-negative cell wall.

Non-Sporeforming
Anaerobes
Non-Sporeforming
Anaerobes
Stains gram-variable or gram-negative,
but not a gram-negative cell wall
Non-Sporeforming
Anaerobes (cont.)
Most Common
Sites of Anaerobic
Infection
Characteristics of
Anaerobic Infection
Characteristic Clinical Signs of
Anaerobic Infection
Anaerobic Gram-Positive
Non-Sporeforming
Bacterial Infections
Gram-Positive
Non-sporeforming
Anaerobes
NOTE:
Figure legend in text
indicates that each of these
organisms is a bacillus (i.e., rodshaped). This is INCORRECT.
Peptostreptococcus is, as the
name indicates, a coccus.
Diseases Associated with
Anaerobic Gram-Positive Bacilli
Gram Stain and Macroscopic
Colonies of Actinomyces
NOTE:
Molar tooth appearance
of colonies on agar can help
remind us that the oral cavity is a
common niche for Actinomyces.
Actinomyces Infections
Cervicofacial Actinomycosis
NOTE:
Sinus tract originating in oral cavity has
made it’s way to the surface at the jawline.
Colonized IUD Resulting in
Pelvic Actinomycosis
Epidemiology
of
Actinomycosis
Sulfur Granule from Sinus Tract of
Actinomycotic Infection
Epidemiology of
Propionibacterium
(doxycycline)
Anaerobic Gram-Negative
Non-Sporeforming
Bacterial Infections
Anaerobic Gram-Negative Infections
Anaerobic Gram-Negative Infections (cont.)
Clinically Predominant Anaerobic Gram-Negatives
Broad Classes of Virulence Factors
Associated with Gram-Neg. Anaerobes
 Adhesins
 Protection from:
• Oxygen toxicity
• Phagocytosis
 Tissue Destruction
Anaerobic Gram-Neg. Virulence Factors
Anaerobic Gram-Negative Virulence
Factors (cont.)
Epidemiology of
Bacteroides
Bacteroides Gram Stain
Bacteroides Virulence Factors
MIXED
Bacteroides
Pathogenicity
[1]
MIXED
[5]
MIXED
[3]
LIVE
[4]
LIVE
[2]
DEAD
[6]
SUBUNIT
[8]
SUBUNIT
[7]
+
+
REVIEW
Non-Sporeforming Anaerobes
Characteristics of
Anaerobic Infection
REVIEW
Characteristic Clinical Signs of
Anaerobic Infection
REVIEW
Most Common
Sites of Anaerobic
Infection
REVIEW
Review of
Anaerobic Gram-Positive
Non-Sporeforming
Bacterial Infections
REVIEW
Gram-Positive
Non-sporeforming
Anaerobes
REVIEW
Actinomyces Infections
REVIEW
Epidemiology
of
Actinomycosis
REVIEW
Epidemiology of
Propionibacterium
(doxycycline)
REVIEW
Review of
Anaerobic Gram-Negative
Non-Sporeforming
Bacterial Infections
REVIEW
Anaerobic Gram-Negative Infections
REVIEW
Anaerobic Gram-Negative Infections (cont.)
REVIEW
Clinically Predominant Anaerobic Gram-Negatives
REVIEW
Broad Classes of Virulence Factors
Associated with Gram-Neg. Anaerobes
 Adhesins
 Protection from:
• Oxygen toxicity
• Phagocytosis
 Tissue Destruction
REVIEW
Anaerobic Gram-Neg. Virulence Factors
REVIEW
Anaerobic Gram-Negative Virulence
Factors (cont.)
REVIEW
Epidemiology of
Bacteroides
REVIEW
Bacteroides Virulence Factors
REVIEW
MIXED
Bacteroides
Pathogenicity
MIXED
[5]
MIXED
[3]
LIVE
[4]
LIVE
[2]
DEAD
[6]
SUBUNIT
[8]
SUBUNIT
[7]
+
+
REVIEW
[1]