Upper Gastrointestinal Cancer The Triumvirate Mr John P Griffith Consultant Gastrointestinal Surgeon The triumvirate Their incidence (per 100 000) • • • • Oesophagus Stomach Pancreas Locally M 14 M 24.3 – oesophagus 52 – stomach–

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Transcript Upper Gastrointestinal Cancer The Triumvirate Mr John P Griffith Consultant Gastrointestinal Surgeon The triumvirate Their incidence (per 100 000) • • • • Oesophagus Stomach Pancreas Locally M 14 M 24.3 – oesophagus 52 – stomach–

Upper Gastrointestinal Cancer
The Triumvirate
Mr John P Griffith
Consultant Gastrointestinal Surgeon
The triumvirate
Their incidence (per 100 000)
•
•
•
•
Oesophagus
Stomach
Pancreas
Locally
M 14
M 24.3
12
– oesophagus 52
– stomach
102
– pancreas
54
(1/3)
(1/2)
(1/20)
F 9
F 14
The triumvirate
Changes in incidence
• Oesophagus
• Gastric
AdenoCA of cardia
increasing
Falling (proximal migration)
• Pancreas
Static
Risk factors
•
•
•
•
•
Age
majority > 70 years
Alcohol
independent and synergistic
Tobacco
Diet
Reflux >5 years (not reduced by PPI)
• Barretts oesophagus
Outcome
1 & 5 year survival rates
• Oesophagus
27%
9%
• Stomach
28%
12%
• Pancreas
12%
3%