US TOO INTERNATIONAL, INC US TOO GREATER QUAD CITIES PROSTATE CANCER SUPPORT GROUP The Anatomy.
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Transcript US TOO INTERNATIONAL, INC US TOO GREATER QUAD CITIES PROSTATE CANCER SUPPORT GROUP The Anatomy.
US TOO
INTERNATIONAL, INC
US TOO GREATER QUAD
CITIES PROSTATE CANCER
SUPPORT GROUP
The Anatomy
STATISTICS:PROSTATE CANCER
• The prostate is the #1 Cancer site in men
• 220K men are diagnosed each year
• The number of new prostate cancer cases will rise
sharply as the “Baby Boomers” come of age
• 29K men die of prostate cancer each year (down
from 40K men that used to die each year before DRE
and PSA screenings were used
• AFRICAN-AMERICAN men have prostate cancer
death rates over twice those of Caucasians
(53.7/100K men VS. 24.1/10K)
• 1 in 6 men will develop Prostate Cancer
• Each person w/ Prostate CA is someone’s
father, uncle, brother, son, etc.
• With early detection, prostate cancer has an 8595% cure rate
• In early stages, treatments are far less traumatic
Relationship of the PSA Level to the
Prevalence of Prostate Cancer and High-Grade Disease
PSA Level
# of men
(N=2950)
0 - 0.5 ng/ml
0.6-1.0 ng/ml
1/1-2/0 ng/ml
2.1-3.0 ng/ml
3.1-4.0 ng/ml
*High-grade
496
791
998
482
193
Men with
Prost. CA
Men with hi-grade
Prost. CA
(N=449)
(N+67)
32(6.6)
80 (10.1)
170 (17.0)
115 (23.9)
52 (26.9)
4/32 (12.5)
8/80 (10.0)
20/170 (11.8)
22/115 (19.1)
13/52 (25.0)
disease = Gleason score > 7. PSA < 4.0 ng/ml.
Reproduced with permission from: Thompson, M, Pauler, DK, Goodman, PJ, et al. N
Engl J Med 2004; 350:2239. Copyright C 2004 Massachusetts Medical. Prevalence
of prostate cancer among men with a prostate-specific antigen level >4.0 ng
Prostate cancer is NOT
just an old man’s disease!
• Literature on prostate cancer usually
states that older men in their 60s or 70s
are more likely to get the disease.
• More men in their late 40s and early 50s
are being diagnosed with prostate cancer.
SYMPTOMS: PROSTATE CANCER
•
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NO SYMPTOMS (EARLY STAGE CA)
Blood in urine
Pain or difficulty urinating
Increased frequency of urination, often at night
Increased urgency to urinate
Inability to urinate
Pain/discomfort in area of prostate (near rectum)
Unexplained weight loss
Unusual, persistent bone pain (usually spine)
PROSTATE CANCER:
THE GENETIC LINK
•
NO FAMILY HISTORY OF
CANCER (CA)
•
1 in 9 (11.2%)
•
FAMILY HISTORY OF CA OTHER
THEN PROSTATE
•
2 in 9 (18.9%)
•
BOTH PARENTS W/ CA OTHER
THEN PROSTATE
•
2 in 5 (42.6%)
•
DAD w/ PROSTATE CA, MOM w/
OTHER CANCER
•
1 in 2 (53.1%)
•
FATHER AND UNCLES(S) WITH
PROSTATE CA
•
3 in 5 (61,7%)
GRAMPA, DAD & UNCLE(S)
HAD PROSTATE CA
•
4 in 5 (86.3%)
•
PROSTATE CANCER
SCREENING
RECOMMENDATIONS
WHO SHOULD BE SCREENED?
Men over 40 w/ risks: Annual DRE &PSA
(African American or w/ family history)
All men by age 45: Annual DRE & PSA
THE “MAN-O-GRAM”
The DRE
THE BENEFITS OF SCREENING
Peace of mind!
Catching prostate CA early
Improving your odds of surviving
Detecting CHANGES in PSA
PSA: WHAT YOU SHOULD KNOW
• PSA stands for Prostate Specific Antigen
• All men should get a baseline PSA by age 45, then
annually thereafter
• All men should know their PSA number
• Men should keep track of changes in their PSA #
over time
• Don’t accept this answer from your Dr:
“Your PSA is normal”
WHAT IS A “GOOD” PSA READING?
• One that stays CONSTANT!
• An increase of 25% in one year means you
should get checked again in 6 months
• If PSA continues to rise sharply, get biopsy
PROSTATE CANCER
TREATMENT OPTIONS
• RADICAL PROSTATECTOMY
– Perineal
– Retropubic*
– Laproscopic*
*Nerve Sparing Procedures
PROSTATE CANCER
TREATMENT OPTIONS
RADIATION THERAPY
• External Radiation
– IMRT: Intensity-Modulated Radiation Therapy
– Conformal Radiation
– 3-D Radiation
– Proton Beam Radiation
PROSTATE CANCER
TREATMENT OPTIONS
• BRACKYTHERAPY (Internal Radiation)
– Paladium Seeds
– Iodine Seeds
– High Dose Therapy
PROSTATE CANCER
TREATMENT OPTIONS
• Hormone Therapy
• Cryotherapy
• Thermal Therapy
• Watchful Waiting
WHAT YOU NEED TO KNOW
ABOUT PROSTATE CANCER
• If you have a family history, include DRE
and PSA in your annual checkups
• Get to know your PSA numbers (make
sure your PSA numbers are stable)
IF YOU HAVE PROSTATE CA
• Know your PSA numbers
• Know your Gleason Score
• Find a support network or group to get
unbiased info on treatment options