US TOO INTERNATIONAL, INC US TOO GREATER QUAD CITIES PROSTATE CANCER SUPPORT GROUP The Anatomy.
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US TOO INTERNATIONAL, INC US TOO GREATER QUAD CITIES PROSTATE CANCER SUPPORT GROUP The Anatomy STATISTICS:PROSTATE CANCER • The prostate is the #1 Cancer site in men • 220K men are diagnosed each year • The number of new prostate cancer cases will rise sharply as the “Baby Boomers” come of age • 29K men die of prostate cancer each year (down from 40K men that used to die each year before DRE and PSA screenings were used • AFRICAN-AMERICAN men have prostate cancer death rates over twice those of Caucasians (53.7/100K men VS. 24.1/10K) • 1 in 6 men will develop Prostate Cancer • Each person w/ Prostate CA is someone’s father, uncle, brother, son, etc. • With early detection, prostate cancer has an 8595% cure rate • In early stages, treatments are far less traumatic Relationship of the PSA Level to the Prevalence of Prostate Cancer and High-Grade Disease PSA Level # of men (N=2950) 0 - 0.5 ng/ml 0.6-1.0 ng/ml 1/1-2/0 ng/ml 2.1-3.0 ng/ml 3.1-4.0 ng/ml *High-grade 496 791 998 482 193 Men with Prost. CA Men with hi-grade Prost. CA (N=449) (N+67) 32(6.6) 80 (10.1) 170 (17.0) 115 (23.9) 52 (26.9) 4/32 (12.5) 8/80 (10.0) 20/170 (11.8) 22/115 (19.1) 13/52 (25.0) disease = Gleason score > 7. PSA < 4.0 ng/ml. Reproduced with permission from: Thompson, M, Pauler, DK, Goodman, PJ, et al. N Engl J Med 2004; 350:2239. Copyright C 2004 Massachusetts Medical. Prevalence of prostate cancer among men with a prostate-specific antigen level >4.0 ng Prostate cancer is NOT just an old man’s disease! • Literature on prostate cancer usually states that older men in their 60s or 70s are more likely to get the disease. • More men in their late 40s and early 50s are being diagnosed with prostate cancer. SYMPTOMS: PROSTATE CANCER • • • • • • • • • NO SYMPTOMS (EARLY STAGE CA) Blood in urine Pain or difficulty urinating Increased frequency of urination, often at night Increased urgency to urinate Inability to urinate Pain/discomfort in area of prostate (near rectum) Unexplained weight loss Unusual, persistent bone pain (usually spine) PROSTATE CANCER: THE GENETIC LINK • NO FAMILY HISTORY OF CANCER (CA) • 1 in 9 (11.2%) • FAMILY HISTORY OF CA OTHER THEN PROSTATE • 2 in 9 (18.9%) • BOTH PARENTS W/ CA OTHER THEN PROSTATE • 2 in 5 (42.6%) • DAD w/ PROSTATE CA, MOM w/ OTHER CANCER • 1 in 2 (53.1%) • FATHER AND UNCLES(S) WITH PROSTATE CA • 3 in 5 (61,7%) GRAMPA, DAD & UNCLE(S) HAD PROSTATE CA • 4 in 5 (86.3%) • PROSTATE CANCER SCREENING RECOMMENDATIONS WHO SHOULD BE SCREENED? Men over 40 w/ risks: Annual DRE &PSA (African American or w/ family history) All men by age 45: Annual DRE & PSA THE “MAN-O-GRAM” The DRE THE BENEFITS OF SCREENING Peace of mind! Catching prostate CA early Improving your odds of surviving Detecting CHANGES in PSA PSA: WHAT YOU SHOULD KNOW • PSA stands for Prostate Specific Antigen • All men should get a baseline PSA by age 45, then annually thereafter • All men should know their PSA number • Men should keep track of changes in their PSA # over time • Don’t accept this answer from your Dr: “Your PSA is normal” WHAT IS A “GOOD” PSA READING? • One that stays CONSTANT! • An increase of 25% in one year means you should get checked again in 6 months • If PSA continues to rise sharply, get biopsy PROSTATE CANCER TREATMENT OPTIONS • RADICAL PROSTATECTOMY – Perineal – Retropubic* – Laproscopic* *Nerve Sparing Procedures PROSTATE CANCER TREATMENT OPTIONS RADIATION THERAPY • External Radiation – IMRT: Intensity-Modulated Radiation Therapy – Conformal Radiation – 3-D Radiation – Proton Beam Radiation PROSTATE CANCER TREATMENT OPTIONS • BRACKYTHERAPY (Internal Radiation) – Paladium Seeds – Iodine Seeds – High Dose Therapy PROSTATE CANCER TREATMENT OPTIONS • Hormone Therapy • Cryotherapy • Thermal Therapy • Watchful Waiting WHAT YOU NEED TO KNOW ABOUT PROSTATE CANCER • If you have a family history, include DRE and PSA in your annual checkups • Get to know your PSA numbers (make sure your PSA numbers are stable) IF YOU HAVE PROSTATE CA • Know your PSA numbers • Know your Gleason Score • Find a support network or group to get unbiased info on treatment options