Transcript HOST PARASITE INTERACTIONS • NORMAL FLORA • DISEASE STATE - PROGRESS OF DISEASE.

HOST PARASITE
INTERACTIONS
• NORMAL FLORA
• DISEASE STATE - PROGRESS OF DISEASE
PROGRESS OF DISEASE
HOW BACTERIA CAUSE
DISEASE
• TOXINS
– EXOTOXINS AND ENDOTOXINS
• SYMPTOMS OF EXOTOXINS AND ENDOTOXINS
• EXOTOXINS – HIGHLY VARIED
– NEUROTOXINS
– CYTOTOXINS
– ENTEROTOXINS
• ENDOTOXINS – ALL THE SAME
– FEVER
– SHOCK
– DIARRHEA
– SOMETIMES INTERNAL HEMORRHAGE AND
ABORTION
• ENZYMES (INVASINS)
– HYALURONIDASE
– COAGULASE
– KINASES
– HEMOLYSINS
– LEUCOCIDINS
• ABILITY TO BE TRANSMITTED
– DIRECT CONTACT
– AIR-BORNE MECHANISM
– FOOD AND WATER-BORNE MECHANISM
– VECTOR MECHANISM
• TISSUE AFFINITY
• INFECTIVE DOSE