Transcript Prediabetes Burden Epidemiology: Health Performance Gaps • Prevalence • Risk factors – Metabolic syndrome – Obesity • Clinical risks of prediabetes – Progression to diabetes • Complications (eg, retinopathy)

Prediabetes
Burden
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Epidemiology:
Health Performance Gaps
• Prevalence
• Risk factors
– Metabolic syndrome
– Obesity
• Clinical risks of prediabetes
– Progression to diabetes
• Complications (eg, retinopathy)
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Progression to Type 2 Diabetes
Impaired
Glucose
Tolerance
Impaired
Fasting
Glucose
Diabetes
Or both
Prediabetes
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Prevalence of Diabetes and
Prediabetes in the United States
140
120
Undiagnosed DM
Diagnosed DM
Persons (millions)
Prediabetes
8.1
7
100
21.0
18.8
80
60
Diabetes
9.1% of US population
5.7
17.9
40
79
86
Prediabetes
37% of US population
57
20
0
2007
2011
2014
CDC. National diabetes fact sheet, 2008. http://www.cdc.gov/diabetes/pubs/pdf/ndfs_2008.pdf.
CDC. National diabetes fact sheet, 2011. http://www.cdc.gov/diabetes/pubs/pdf/ndfs_2011.pdf.
CDC. National diabetes statistics report, 2014. http://www.cdc.gov/diabetes/pubs/statsreport14/national-diabetes-report-web.pdf
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Prevalence of IFG and IGT in US
Adults Without T2D
NHANES 2005-2006
(N=1547)
40
US Population (%)
35
34.6%
30
25
19.4%
20
15
9.8%
10
5.4%
5
0
Prediabetes
IFG only
IGT only
IFG and IGT
IFG, impaired fasting glucose; IGT, impaired glucose tolerance; NHANES, National Health and Nutrition Examination Survey;
T2D, type 2 diabetes.
Karve A, Hayward RA. Diabetes Care. 2010;33:2355-2359.
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