CHLORHEXIDINE Dr. Shahzadi Tayyaba Hashmi [email protected] CHLORHEXIDINE GLUCONATE • Chlorhexidine gluconate is an effective bactericidal agent and broad-spectrum antimicrobial drug • It has been extensively researched and is the “gold.
Download ReportTranscript CHLORHEXIDINE Dr. Shahzadi Tayyaba Hashmi [email protected] CHLORHEXIDINE GLUCONATE • Chlorhexidine gluconate is an effective bactericidal agent and broad-spectrum antimicrobial drug • It has been extensively researched and is the “gold.
Slide 1
CHLORHEXIDINE
Dr. Shahzadi Tayyaba
Hashmi
[email protected]
CHLORHEXIDINE
GLUCONATE
• Chlorhexidine gluconate is an effective
bactericidal agent and broad-spectrum
antimicrobial drug
• It has been extensively researched and is the
“gold standard” antimicrobial in oral hygiene
• Chlorhexidine is useful in many clinical
disciplines including periodontics, endodontics,
oral surgery and operative dentistry
INTRODUCTION
• Chlorhexidine is a broad-spectrum antimicrobial drug
• Acting as an antiseptic, it is an effective bactericidal
agent against all categories of microbes, including
bacteria, yeast and viruses
• Chlorhexidine was first used as a mouth rinse as an
adjunct to conventional non-surgical periodontal
therapy
• Chlorhexidine has proven efficacy as a broad-spectrum
antimicrobial for reducing supragingival plaque
PREVENTION OF DENTAL
CARIES
• There are a number of theories concerning the development and progression of
dental caries
• According to the specific Plaque hypothesis, only a limited number of bacteria
found in dental plaque can produce dental caries
• The most prominent among these bacteria are streptococcus mutans and
Lactobacilli
• Streptococcus mutans represent a group of closely related bacterial species that
are the primary species that initiate enamel caries
• Therefore patients with low mutans streptococci population levels in their oral
cavity generally have low caries activity and patients with high mutans
streptococci population levels generally high caries activity
• Lactobacilli are the primary causative species of dentinal caries
PREVENTION OF DENTAL
CARIES
• Chlorhexidine is a very potent bactericidal agent
for streptococcus mutans, the most significant
group of bacterium associated with dental caries
• Chlorhexidine molecules adhere to the surfaces
of streptococcus mutans and produce cell death
• For patients with a high risk of caries,
chlorhexidine rinses can be successfully used to
reduce the number of odontopathogenic bacteria
WHAT MAKES CHX UNIQUE
• Its long lasting bacteriostatic action, also termed as
‘substantivity’
• Its action lasts for about 12 hours in the oral cavity after a
single rinse
• The di-cationic CHX molecule, attaches to the pellicle by one
cation, to the bacteria attempting to colonize the tooth surface
with the other. This is called the ‘Pin-Cushion Effect’
• This prolongs the CHX action
USES
1. As an adjunct to oral hygiene
2. Post oral surgery including periodontal surgery or root
planning
3. In patients with inter maxillary fixation.
4. For oral hygiene & gingival health in physically & mentally
handicapped
5. Medically compromised individuals predisposed to oral
infections
6. High caries risk patient
7. Recurrent oral ulceration
8. Removable & fixed orthodontic wearers
9. Treatment of denture stomatitis and dry socket
10. As an immediate prophylactic rinse in the prevention of postextraction bacteremia
ADVERSE EFFECTS
a)
b)
c)
d)
e)
f)
Extrinsic staining
Alteration in taste perception
Oral mucosal erosion
Enhanced supragingival calculus formation
Parotid gland swelling
Over dosage ingestion of 1 or 2 ounces of CHX oral rinse by
a small child might result in gastric distress, including nausea
or signs of alcohol intoxication
DOSES AND ADMINISTRATION
• Recommended use is twice daily oral rinsing for 30 seconds
after tooth brushing
• Usual dosage is 15ml (1 tablespoon) of undiluted
chlorhexidine oral rinse
• Patient should be instructed not to rinse with water or brush
teeth or eat immediately after CHX oral rinse
• CHX should not be ingested and should be expectorated after
rinsing
AVAILABLE
FORMULATIONS
• Mouth rinse- aqueous/ alcohol solutions of 0.2% [Zordyl
,Clorasept]
• Gel [corsodyl dental gel]
• Sprays [Hibispray]
• Tooth pastes
• Varnishes
• Chewing gums
• Periodontal dressings
• Subgingival plaque control [Periochip]
THANK YOU
Slide 2
CHLORHEXIDINE
Dr. Shahzadi Tayyaba
Hashmi
[email protected]
CHLORHEXIDINE
GLUCONATE
• Chlorhexidine gluconate is an effective
bactericidal agent and broad-spectrum
antimicrobial drug
• It has been extensively researched and is the
“gold standard” antimicrobial in oral hygiene
• Chlorhexidine is useful in many clinical
disciplines including periodontics, endodontics,
oral surgery and operative dentistry
INTRODUCTION
• Chlorhexidine is a broad-spectrum antimicrobial drug
• Acting as an antiseptic, it is an effective bactericidal
agent against all categories of microbes, including
bacteria, yeast and viruses
• Chlorhexidine was first used as a mouth rinse as an
adjunct to conventional non-surgical periodontal
therapy
• Chlorhexidine has proven efficacy as a broad-spectrum
antimicrobial for reducing supragingival plaque
PREVENTION OF DENTAL
CARIES
• There are a number of theories concerning the development and progression of
dental caries
• According to the specific Plaque hypothesis, only a limited number of bacteria
found in dental plaque can produce dental caries
• The most prominent among these bacteria are streptococcus mutans and
Lactobacilli
• Streptococcus mutans represent a group of closely related bacterial species that
are the primary species that initiate enamel caries
• Therefore patients with low mutans streptococci population levels in their oral
cavity generally have low caries activity and patients with high mutans
streptococci population levels generally high caries activity
• Lactobacilli are the primary causative species of dentinal caries
PREVENTION OF DENTAL
CARIES
• Chlorhexidine is a very potent bactericidal agent
for streptococcus mutans, the most significant
group of bacterium associated with dental caries
• Chlorhexidine molecules adhere to the surfaces
of streptococcus mutans and produce cell death
• For patients with a high risk of caries,
chlorhexidine rinses can be successfully used to
reduce the number of odontopathogenic bacteria
WHAT MAKES CHX UNIQUE
• Its long lasting bacteriostatic action, also termed as
‘substantivity’
• Its action lasts for about 12 hours in the oral cavity after a
single rinse
• The di-cationic CHX molecule, attaches to the pellicle by one
cation, to the bacteria attempting to colonize the tooth surface
with the other. This is called the ‘Pin-Cushion Effect’
• This prolongs the CHX action
USES
1. As an adjunct to oral hygiene
2. Post oral surgery including periodontal surgery or root
planning
3. In patients with inter maxillary fixation.
4. For oral hygiene & gingival health in physically & mentally
handicapped
5. Medically compromised individuals predisposed to oral
infections
6. High caries risk patient
7. Recurrent oral ulceration
8. Removable & fixed orthodontic wearers
9. Treatment of denture stomatitis and dry socket
10. As an immediate prophylactic rinse in the prevention of postextraction bacteremia
ADVERSE EFFECTS
a)
b)
c)
d)
e)
f)
Extrinsic staining
Alteration in taste perception
Oral mucosal erosion
Enhanced supragingival calculus formation
Parotid gland swelling
Over dosage ingestion of 1 or 2 ounces of CHX oral rinse by
a small child might result in gastric distress, including nausea
or signs of alcohol intoxication
DOSES AND ADMINISTRATION
• Recommended use is twice daily oral rinsing for 30 seconds
after tooth brushing
• Usual dosage is 15ml (1 tablespoon) of undiluted
chlorhexidine oral rinse
• Patient should be instructed not to rinse with water or brush
teeth or eat immediately after CHX oral rinse
• CHX should not be ingested and should be expectorated after
rinsing
AVAILABLE
FORMULATIONS
• Mouth rinse- aqueous/ alcohol solutions of 0.2% [Zordyl
,Clorasept]
• Gel [corsodyl dental gel]
• Sprays [Hibispray]
• Tooth pastes
• Varnishes
• Chewing gums
• Periodontal dressings
• Subgingival plaque control [Periochip]
THANK YOU
Slide 3
CHLORHEXIDINE
Dr. Shahzadi Tayyaba
Hashmi
[email protected]
CHLORHEXIDINE
GLUCONATE
• Chlorhexidine gluconate is an effective
bactericidal agent and broad-spectrum
antimicrobial drug
• It has been extensively researched and is the
“gold standard” antimicrobial in oral hygiene
• Chlorhexidine is useful in many clinical
disciplines including periodontics, endodontics,
oral surgery and operative dentistry
INTRODUCTION
• Chlorhexidine is a broad-spectrum antimicrobial drug
• Acting as an antiseptic, it is an effective bactericidal
agent against all categories of microbes, including
bacteria, yeast and viruses
• Chlorhexidine was first used as a mouth rinse as an
adjunct to conventional non-surgical periodontal
therapy
• Chlorhexidine has proven efficacy as a broad-spectrum
antimicrobial for reducing supragingival plaque
PREVENTION OF DENTAL
CARIES
• There are a number of theories concerning the development and progression of
dental caries
• According to the specific Plaque hypothesis, only a limited number of bacteria
found in dental plaque can produce dental caries
• The most prominent among these bacteria are streptococcus mutans and
Lactobacilli
• Streptococcus mutans represent a group of closely related bacterial species that
are the primary species that initiate enamel caries
• Therefore patients with low mutans streptococci population levels in their oral
cavity generally have low caries activity and patients with high mutans
streptococci population levels generally high caries activity
• Lactobacilli are the primary causative species of dentinal caries
PREVENTION OF DENTAL
CARIES
• Chlorhexidine is a very potent bactericidal agent
for streptococcus mutans, the most significant
group of bacterium associated with dental caries
• Chlorhexidine molecules adhere to the surfaces
of streptococcus mutans and produce cell death
• For patients with a high risk of caries,
chlorhexidine rinses can be successfully used to
reduce the number of odontopathogenic bacteria
WHAT MAKES CHX UNIQUE
• Its long lasting bacteriostatic action, also termed as
‘substantivity’
• Its action lasts for about 12 hours in the oral cavity after a
single rinse
• The di-cationic CHX molecule, attaches to the pellicle by one
cation, to the bacteria attempting to colonize the tooth surface
with the other. This is called the ‘Pin-Cushion Effect’
• This prolongs the CHX action
USES
1. As an adjunct to oral hygiene
2. Post oral surgery including periodontal surgery or root
planning
3. In patients with inter maxillary fixation.
4. For oral hygiene & gingival health in physically & mentally
handicapped
5. Medically compromised individuals predisposed to oral
infections
6. High caries risk patient
7. Recurrent oral ulceration
8. Removable & fixed orthodontic wearers
9. Treatment of denture stomatitis and dry socket
10. As an immediate prophylactic rinse in the prevention of postextraction bacteremia
ADVERSE EFFECTS
a)
b)
c)
d)
e)
f)
Extrinsic staining
Alteration in taste perception
Oral mucosal erosion
Enhanced supragingival calculus formation
Parotid gland swelling
Over dosage ingestion of 1 or 2 ounces of CHX oral rinse by
a small child might result in gastric distress, including nausea
or signs of alcohol intoxication
DOSES AND ADMINISTRATION
• Recommended use is twice daily oral rinsing for 30 seconds
after tooth brushing
• Usual dosage is 15ml (1 tablespoon) of undiluted
chlorhexidine oral rinse
• Patient should be instructed not to rinse with water or brush
teeth or eat immediately after CHX oral rinse
• CHX should not be ingested and should be expectorated after
rinsing
AVAILABLE
FORMULATIONS
• Mouth rinse- aqueous/ alcohol solutions of 0.2% [Zordyl
,Clorasept]
• Gel [corsodyl dental gel]
• Sprays [Hibispray]
• Tooth pastes
• Varnishes
• Chewing gums
• Periodontal dressings
• Subgingival plaque control [Periochip]
THANK YOU
Slide 4
CHLORHEXIDINE
Dr. Shahzadi Tayyaba
Hashmi
[email protected]
CHLORHEXIDINE
GLUCONATE
• Chlorhexidine gluconate is an effective
bactericidal agent and broad-spectrum
antimicrobial drug
• It has been extensively researched and is the
“gold standard” antimicrobial in oral hygiene
• Chlorhexidine is useful in many clinical
disciplines including periodontics, endodontics,
oral surgery and operative dentistry
INTRODUCTION
• Chlorhexidine is a broad-spectrum antimicrobial drug
• Acting as an antiseptic, it is an effective bactericidal
agent against all categories of microbes, including
bacteria, yeast and viruses
• Chlorhexidine was first used as a mouth rinse as an
adjunct to conventional non-surgical periodontal
therapy
• Chlorhexidine has proven efficacy as a broad-spectrum
antimicrobial for reducing supragingival plaque
PREVENTION OF DENTAL
CARIES
• There are a number of theories concerning the development and progression of
dental caries
• According to the specific Plaque hypothesis, only a limited number of bacteria
found in dental plaque can produce dental caries
• The most prominent among these bacteria are streptococcus mutans and
Lactobacilli
• Streptococcus mutans represent a group of closely related bacterial species that
are the primary species that initiate enamel caries
• Therefore patients with low mutans streptococci population levels in their oral
cavity generally have low caries activity and patients with high mutans
streptococci population levels generally high caries activity
• Lactobacilli are the primary causative species of dentinal caries
PREVENTION OF DENTAL
CARIES
• Chlorhexidine is a very potent bactericidal agent
for streptococcus mutans, the most significant
group of bacterium associated with dental caries
• Chlorhexidine molecules adhere to the surfaces
of streptococcus mutans and produce cell death
• For patients with a high risk of caries,
chlorhexidine rinses can be successfully used to
reduce the number of odontopathogenic bacteria
WHAT MAKES CHX UNIQUE
• Its long lasting bacteriostatic action, also termed as
‘substantivity’
• Its action lasts for about 12 hours in the oral cavity after a
single rinse
• The di-cationic CHX molecule, attaches to the pellicle by one
cation, to the bacteria attempting to colonize the tooth surface
with the other. This is called the ‘Pin-Cushion Effect’
• This prolongs the CHX action
USES
1. As an adjunct to oral hygiene
2. Post oral surgery including periodontal surgery or root
planning
3. In patients with inter maxillary fixation.
4. For oral hygiene & gingival health in physically & mentally
handicapped
5. Medically compromised individuals predisposed to oral
infections
6. High caries risk patient
7. Recurrent oral ulceration
8. Removable & fixed orthodontic wearers
9. Treatment of denture stomatitis and dry socket
10. As an immediate prophylactic rinse in the prevention of postextraction bacteremia
ADVERSE EFFECTS
a)
b)
c)
d)
e)
f)
Extrinsic staining
Alteration in taste perception
Oral mucosal erosion
Enhanced supragingival calculus formation
Parotid gland swelling
Over dosage ingestion of 1 or 2 ounces of CHX oral rinse by
a small child might result in gastric distress, including nausea
or signs of alcohol intoxication
DOSES AND ADMINISTRATION
• Recommended use is twice daily oral rinsing for 30 seconds
after tooth brushing
• Usual dosage is 15ml (1 tablespoon) of undiluted
chlorhexidine oral rinse
• Patient should be instructed not to rinse with water or brush
teeth or eat immediately after CHX oral rinse
• CHX should not be ingested and should be expectorated after
rinsing
AVAILABLE
FORMULATIONS
• Mouth rinse- aqueous/ alcohol solutions of 0.2% [Zordyl
,Clorasept]
• Gel [corsodyl dental gel]
• Sprays [Hibispray]
• Tooth pastes
• Varnishes
• Chewing gums
• Periodontal dressings
• Subgingival plaque control [Periochip]
THANK YOU
Slide 5
CHLORHEXIDINE
Dr. Shahzadi Tayyaba
Hashmi
[email protected]
CHLORHEXIDINE
GLUCONATE
• Chlorhexidine gluconate is an effective
bactericidal agent and broad-spectrum
antimicrobial drug
• It has been extensively researched and is the
“gold standard” antimicrobial in oral hygiene
• Chlorhexidine is useful in many clinical
disciplines including periodontics, endodontics,
oral surgery and operative dentistry
INTRODUCTION
• Chlorhexidine is a broad-spectrum antimicrobial drug
• Acting as an antiseptic, it is an effective bactericidal
agent against all categories of microbes, including
bacteria, yeast and viruses
• Chlorhexidine was first used as a mouth rinse as an
adjunct to conventional non-surgical periodontal
therapy
• Chlorhexidine has proven efficacy as a broad-spectrum
antimicrobial for reducing supragingival plaque
PREVENTION OF DENTAL
CARIES
• There are a number of theories concerning the development and progression of
dental caries
• According to the specific Plaque hypothesis, only a limited number of bacteria
found in dental plaque can produce dental caries
• The most prominent among these bacteria are streptococcus mutans and
Lactobacilli
• Streptococcus mutans represent a group of closely related bacterial species that
are the primary species that initiate enamel caries
• Therefore patients with low mutans streptococci population levels in their oral
cavity generally have low caries activity and patients with high mutans
streptococci population levels generally high caries activity
• Lactobacilli are the primary causative species of dentinal caries
PREVENTION OF DENTAL
CARIES
• Chlorhexidine is a very potent bactericidal agent
for streptococcus mutans, the most significant
group of bacterium associated with dental caries
• Chlorhexidine molecules adhere to the surfaces
of streptococcus mutans and produce cell death
• For patients with a high risk of caries,
chlorhexidine rinses can be successfully used to
reduce the number of odontopathogenic bacteria
WHAT MAKES CHX UNIQUE
• Its long lasting bacteriostatic action, also termed as
‘substantivity’
• Its action lasts for about 12 hours in the oral cavity after a
single rinse
• The di-cationic CHX molecule, attaches to the pellicle by one
cation, to the bacteria attempting to colonize the tooth surface
with the other. This is called the ‘Pin-Cushion Effect’
• This prolongs the CHX action
USES
1. As an adjunct to oral hygiene
2. Post oral surgery including periodontal surgery or root
planning
3. In patients with inter maxillary fixation.
4. For oral hygiene & gingival health in physically & mentally
handicapped
5. Medically compromised individuals predisposed to oral
infections
6. High caries risk patient
7. Recurrent oral ulceration
8. Removable & fixed orthodontic wearers
9. Treatment of denture stomatitis and dry socket
10. As an immediate prophylactic rinse in the prevention of postextraction bacteremia
ADVERSE EFFECTS
a)
b)
c)
d)
e)
f)
Extrinsic staining
Alteration in taste perception
Oral mucosal erosion
Enhanced supragingival calculus formation
Parotid gland swelling
Over dosage ingestion of 1 or 2 ounces of CHX oral rinse by
a small child might result in gastric distress, including nausea
or signs of alcohol intoxication
DOSES AND ADMINISTRATION
• Recommended use is twice daily oral rinsing for 30 seconds
after tooth brushing
• Usual dosage is 15ml (1 tablespoon) of undiluted
chlorhexidine oral rinse
• Patient should be instructed not to rinse with water or brush
teeth or eat immediately after CHX oral rinse
• CHX should not be ingested and should be expectorated after
rinsing
AVAILABLE
FORMULATIONS
• Mouth rinse- aqueous/ alcohol solutions of 0.2% [Zordyl
,Clorasept]
• Gel [corsodyl dental gel]
• Sprays [Hibispray]
• Tooth pastes
• Varnishes
• Chewing gums
• Periodontal dressings
• Subgingival plaque control [Periochip]
THANK YOU
Slide 6
CHLORHEXIDINE
Dr. Shahzadi Tayyaba
Hashmi
[email protected]
CHLORHEXIDINE
GLUCONATE
• Chlorhexidine gluconate is an effective
bactericidal agent and broad-spectrum
antimicrobial drug
• It has been extensively researched and is the
“gold standard” antimicrobial in oral hygiene
• Chlorhexidine is useful in many clinical
disciplines including periodontics, endodontics,
oral surgery and operative dentistry
INTRODUCTION
• Chlorhexidine is a broad-spectrum antimicrobial drug
• Acting as an antiseptic, it is an effective bactericidal
agent against all categories of microbes, including
bacteria, yeast and viruses
• Chlorhexidine was first used as a mouth rinse as an
adjunct to conventional non-surgical periodontal
therapy
• Chlorhexidine has proven efficacy as a broad-spectrum
antimicrobial for reducing supragingival plaque
PREVENTION OF DENTAL
CARIES
• There are a number of theories concerning the development and progression of
dental caries
• According to the specific Plaque hypothesis, only a limited number of bacteria
found in dental plaque can produce dental caries
• The most prominent among these bacteria are streptococcus mutans and
Lactobacilli
• Streptococcus mutans represent a group of closely related bacterial species that
are the primary species that initiate enamel caries
• Therefore patients with low mutans streptococci population levels in their oral
cavity generally have low caries activity and patients with high mutans
streptococci population levels generally high caries activity
• Lactobacilli are the primary causative species of dentinal caries
PREVENTION OF DENTAL
CARIES
• Chlorhexidine is a very potent bactericidal agent
for streptococcus mutans, the most significant
group of bacterium associated with dental caries
• Chlorhexidine molecules adhere to the surfaces
of streptococcus mutans and produce cell death
• For patients with a high risk of caries,
chlorhexidine rinses can be successfully used to
reduce the number of odontopathogenic bacteria
WHAT MAKES CHX UNIQUE
• Its long lasting bacteriostatic action, also termed as
‘substantivity’
• Its action lasts for about 12 hours in the oral cavity after a
single rinse
• The di-cationic CHX molecule, attaches to the pellicle by one
cation, to the bacteria attempting to colonize the tooth surface
with the other. This is called the ‘Pin-Cushion Effect’
• This prolongs the CHX action
USES
1. As an adjunct to oral hygiene
2. Post oral surgery including periodontal surgery or root
planning
3. In patients with inter maxillary fixation.
4. For oral hygiene & gingival health in physically & mentally
handicapped
5. Medically compromised individuals predisposed to oral
infections
6. High caries risk patient
7. Recurrent oral ulceration
8. Removable & fixed orthodontic wearers
9. Treatment of denture stomatitis and dry socket
10. As an immediate prophylactic rinse in the prevention of postextraction bacteremia
ADVERSE EFFECTS
a)
b)
c)
d)
e)
f)
Extrinsic staining
Alteration in taste perception
Oral mucosal erosion
Enhanced supragingival calculus formation
Parotid gland swelling
Over dosage ingestion of 1 or 2 ounces of CHX oral rinse by
a small child might result in gastric distress, including nausea
or signs of alcohol intoxication
DOSES AND ADMINISTRATION
• Recommended use is twice daily oral rinsing for 30 seconds
after tooth brushing
• Usual dosage is 15ml (1 tablespoon) of undiluted
chlorhexidine oral rinse
• Patient should be instructed not to rinse with water or brush
teeth or eat immediately after CHX oral rinse
• CHX should not be ingested and should be expectorated after
rinsing
AVAILABLE
FORMULATIONS
• Mouth rinse- aqueous/ alcohol solutions of 0.2% [Zordyl
,Clorasept]
• Gel [corsodyl dental gel]
• Sprays [Hibispray]
• Tooth pastes
• Varnishes
• Chewing gums
• Periodontal dressings
• Subgingival plaque control [Periochip]
THANK YOU
Slide 7
CHLORHEXIDINE
Dr. Shahzadi Tayyaba
Hashmi
[email protected]
CHLORHEXIDINE
GLUCONATE
• Chlorhexidine gluconate is an effective
bactericidal agent and broad-spectrum
antimicrobial drug
• It has been extensively researched and is the
“gold standard” antimicrobial in oral hygiene
• Chlorhexidine is useful in many clinical
disciplines including periodontics, endodontics,
oral surgery and operative dentistry
INTRODUCTION
• Chlorhexidine is a broad-spectrum antimicrobial drug
• Acting as an antiseptic, it is an effective bactericidal
agent against all categories of microbes, including
bacteria, yeast and viruses
• Chlorhexidine was first used as a mouth rinse as an
adjunct to conventional non-surgical periodontal
therapy
• Chlorhexidine has proven efficacy as a broad-spectrum
antimicrobial for reducing supragingival plaque
PREVENTION OF DENTAL
CARIES
• There are a number of theories concerning the development and progression of
dental caries
• According to the specific Plaque hypothesis, only a limited number of bacteria
found in dental plaque can produce dental caries
• The most prominent among these bacteria are streptococcus mutans and
Lactobacilli
• Streptococcus mutans represent a group of closely related bacterial species that
are the primary species that initiate enamel caries
• Therefore patients with low mutans streptococci population levels in their oral
cavity generally have low caries activity and patients with high mutans
streptococci population levels generally high caries activity
• Lactobacilli are the primary causative species of dentinal caries
PREVENTION OF DENTAL
CARIES
• Chlorhexidine is a very potent bactericidal agent
for streptococcus mutans, the most significant
group of bacterium associated with dental caries
• Chlorhexidine molecules adhere to the surfaces
of streptococcus mutans and produce cell death
• For patients with a high risk of caries,
chlorhexidine rinses can be successfully used to
reduce the number of odontopathogenic bacteria
WHAT MAKES CHX UNIQUE
• Its long lasting bacteriostatic action, also termed as
‘substantivity’
• Its action lasts for about 12 hours in the oral cavity after a
single rinse
• The di-cationic CHX molecule, attaches to the pellicle by one
cation, to the bacteria attempting to colonize the tooth surface
with the other. This is called the ‘Pin-Cushion Effect’
• This prolongs the CHX action
USES
1. As an adjunct to oral hygiene
2. Post oral surgery including periodontal surgery or root
planning
3. In patients with inter maxillary fixation.
4. For oral hygiene & gingival health in physically & mentally
handicapped
5. Medically compromised individuals predisposed to oral
infections
6. High caries risk patient
7. Recurrent oral ulceration
8. Removable & fixed orthodontic wearers
9. Treatment of denture stomatitis and dry socket
10. As an immediate prophylactic rinse in the prevention of postextraction bacteremia
ADVERSE EFFECTS
a)
b)
c)
d)
e)
f)
Extrinsic staining
Alteration in taste perception
Oral mucosal erosion
Enhanced supragingival calculus formation
Parotid gland swelling
Over dosage ingestion of 1 or 2 ounces of CHX oral rinse by
a small child might result in gastric distress, including nausea
or signs of alcohol intoxication
DOSES AND ADMINISTRATION
• Recommended use is twice daily oral rinsing for 30 seconds
after tooth brushing
• Usual dosage is 15ml (1 tablespoon) of undiluted
chlorhexidine oral rinse
• Patient should be instructed not to rinse with water or brush
teeth or eat immediately after CHX oral rinse
• CHX should not be ingested and should be expectorated after
rinsing
AVAILABLE
FORMULATIONS
• Mouth rinse- aqueous/ alcohol solutions of 0.2% [Zordyl
,Clorasept]
• Gel [corsodyl dental gel]
• Sprays [Hibispray]
• Tooth pastes
• Varnishes
• Chewing gums
• Periodontal dressings
• Subgingival plaque control [Periochip]
THANK YOU
Slide 8
CHLORHEXIDINE
Dr. Shahzadi Tayyaba
Hashmi
[email protected]
CHLORHEXIDINE
GLUCONATE
• Chlorhexidine gluconate is an effective
bactericidal agent and broad-spectrum
antimicrobial drug
• It has been extensively researched and is the
“gold standard” antimicrobial in oral hygiene
• Chlorhexidine is useful in many clinical
disciplines including periodontics, endodontics,
oral surgery and operative dentistry
INTRODUCTION
• Chlorhexidine is a broad-spectrum antimicrobial drug
• Acting as an antiseptic, it is an effective bactericidal
agent against all categories of microbes, including
bacteria, yeast and viruses
• Chlorhexidine was first used as a mouth rinse as an
adjunct to conventional non-surgical periodontal
therapy
• Chlorhexidine has proven efficacy as a broad-spectrum
antimicrobial for reducing supragingival plaque
PREVENTION OF DENTAL
CARIES
• There are a number of theories concerning the development and progression of
dental caries
• According to the specific Plaque hypothesis, only a limited number of bacteria
found in dental plaque can produce dental caries
• The most prominent among these bacteria are streptococcus mutans and
Lactobacilli
• Streptococcus mutans represent a group of closely related bacterial species that
are the primary species that initiate enamel caries
• Therefore patients with low mutans streptococci population levels in their oral
cavity generally have low caries activity and patients with high mutans
streptococci population levels generally high caries activity
• Lactobacilli are the primary causative species of dentinal caries
PREVENTION OF DENTAL
CARIES
• Chlorhexidine is a very potent bactericidal agent
for streptococcus mutans, the most significant
group of bacterium associated with dental caries
• Chlorhexidine molecules adhere to the surfaces
of streptococcus mutans and produce cell death
• For patients with a high risk of caries,
chlorhexidine rinses can be successfully used to
reduce the number of odontopathogenic bacteria
WHAT MAKES CHX UNIQUE
• Its long lasting bacteriostatic action, also termed as
‘substantivity’
• Its action lasts for about 12 hours in the oral cavity after a
single rinse
• The di-cationic CHX molecule, attaches to the pellicle by one
cation, to the bacteria attempting to colonize the tooth surface
with the other. This is called the ‘Pin-Cushion Effect’
• This prolongs the CHX action
USES
1. As an adjunct to oral hygiene
2. Post oral surgery including periodontal surgery or root
planning
3. In patients with inter maxillary fixation.
4. For oral hygiene & gingival health in physically & mentally
handicapped
5. Medically compromised individuals predisposed to oral
infections
6. High caries risk patient
7. Recurrent oral ulceration
8. Removable & fixed orthodontic wearers
9. Treatment of denture stomatitis and dry socket
10. As an immediate prophylactic rinse in the prevention of postextraction bacteremia
ADVERSE EFFECTS
a)
b)
c)
d)
e)
f)
Extrinsic staining
Alteration in taste perception
Oral mucosal erosion
Enhanced supragingival calculus formation
Parotid gland swelling
Over dosage ingestion of 1 or 2 ounces of CHX oral rinse by
a small child might result in gastric distress, including nausea
or signs of alcohol intoxication
DOSES AND ADMINISTRATION
• Recommended use is twice daily oral rinsing for 30 seconds
after tooth brushing
• Usual dosage is 15ml (1 tablespoon) of undiluted
chlorhexidine oral rinse
• Patient should be instructed not to rinse with water or brush
teeth or eat immediately after CHX oral rinse
• CHX should not be ingested and should be expectorated after
rinsing
AVAILABLE
FORMULATIONS
• Mouth rinse- aqueous/ alcohol solutions of 0.2% [Zordyl
,Clorasept]
• Gel [corsodyl dental gel]
• Sprays [Hibispray]
• Tooth pastes
• Varnishes
• Chewing gums
• Periodontal dressings
• Subgingival plaque control [Periochip]
THANK YOU
Slide 9
CHLORHEXIDINE
Dr. Shahzadi Tayyaba
Hashmi
[email protected]
CHLORHEXIDINE
GLUCONATE
• Chlorhexidine gluconate is an effective
bactericidal agent and broad-spectrum
antimicrobial drug
• It has been extensively researched and is the
“gold standard” antimicrobial in oral hygiene
• Chlorhexidine is useful in many clinical
disciplines including periodontics, endodontics,
oral surgery and operative dentistry
INTRODUCTION
• Chlorhexidine is a broad-spectrum antimicrobial drug
• Acting as an antiseptic, it is an effective bactericidal
agent against all categories of microbes, including
bacteria, yeast and viruses
• Chlorhexidine was first used as a mouth rinse as an
adjunct to conventional non-surgical periodontal
therapy
• Chlorhexidine has proven efficacy as a broad-spectrum
antimicrobial for reducing supragingival plaque
PREVENTION OF DENTAL
CARIES
• There are a number of theories concerning the development and progression of
dental caries
• According to the specific Plaque hypothesis, only a limited number of bacteria
found in dental plaque can produce dental caries
• The most prominent among these bacteria are streptococcus mutans and
Lactobacilli
• Streptococcus mutans represent a group of closely related bacterial species that
are the primary species that initiate enamel caries
• Therefore patients with low mutans streptococci population levels in their oral
cavity generally have low caries activity and patients with high mutans
streptococci population levels generally high caries activity
• Lactobacilli are the primary causative species of dentinal caries
PREVENTION OF DENTAL
CARIES
• Chlorhexidine is a very potent bactericidal agent
for streptococcus mutans, the most significant
group of bacterium associated with dental caries
• Chlorhexidine molecules adhere to the surfaces
of streptococcus mutans and produce cell death
• For patients with a high risk of caries,
chlorhexidine rinses can be successfully used to
reduce the number of odontopathogenic bacteria
WHAT MAKES CHX UNIQUE
• Its long lasting bacteriostatic action, also termed as
‘substantivity’
• Its action lasts for about 12 hours in the oral cavity after a
single rinse
• The di-cationic CHX molecule, attaches to the pellicle by one
cation, to the bacteria attempting to colonize the tooth surface
with the other. This is called the ‘Pin-Cushion Effect’
• This prolongs the CHX action
USES
1. As an adjunct to oral hygiene
2. Post oral surgery including periodontal surgery or root
planning
3. In patients with inter maxillary fixation.
4. For oral hygiene & gingival health in physically & mentally
handicapped
5. Medically compromised individuals predisposed to oral
infections
6. High caries risk patient
7. Recurrent oral ulceration
8. Removable & fixed orthodontic wearers
9. Treatment of denture stomatitis and dry socket
10. As an immediate prophylactic rinse in the prevention of postextraction bacteremia
ADVERSE EFFECTS
a)
b)
c)
d)
e)
f)
Extrinsic staining
Alteration in taste perception
Oral mucosal erosion
Enhanced supragingival calculus formation
Parotid gland swelling
Over dosage ingestion of 1 or 2 ounces of CHX oral rinse by
a small child might result in gastric distress, including nausea
or signs of alcohol intoxication
DOSES AND ADMINISTRATION
• Recommended use is twice daily oral rinsing for 30 seconds
after tooth brushing
• Usual dosage is 15ml (1 tablespoon) of undiluted
chlorhexidine oral rinse
• Patient should be instructed not to rinse with water or brush
teeth or eat immediately after CHX oral rinse
• CHX should not be ingested and should be expectorated after
rinsing
AVAILABLE
FORMULATIONS
• Mouth rinse- aqueous/ alcohol solutions of 0.2% [Zordyl
,Clorasept]
• Gel [corsodyl dental gel]
• Sprays [Hibispray]
• Tooth pastes
• Varnishes
• Chewing gums
• Periodontal dressings
• Subgingival plaque control [Periochip]
THANK YOU
Slide 10
CHLORHEXIDINE
Dr. Shahzadi Tayyaba
Hashmi
[email protected]
CHLORHEXIDINE
GLUCONATE
• Chlorhexidine gluconate is an effective
bactericidal agent and broad-spectrum
antimicrobial drug
• It has been extensively researched and is the
“gold standard” antimicrobial in oral hygiene
• Chlorhexidine is useful in many clinical
disciplines including periodontics, endodontics,
oral surgery and operative dentistry
INTRODUCTION
• Chlorhexidine is a broad-spectrum antimicrobial drug
• Acting as an antiseptic, it is an effective bactericidal
agent against all categories of microbes, including
bacteria, yeast and viruses
• Chlorhexidine was first used as a mouth rinse as an
adjunct to conventional non-surgical periodontal
therapy
• Chlorhexidine has proven efficacy as a broad-spectrum
antimicrobial for reducing supragingival plaque
PREVENTION OF DENTAL
CARIES
• There are a number of theories concerning the development and progression of
dental caries
• According to the specific Plaque hypothesis, only a limited number of bacteria
found in dental plaque can produce dental caries
• The most prominent among these bacteria are streptococcus mutans and
Lactobacilli
• Streptococcus mutans represent a group of closely related bacterial species that
are the primary species that initiate enamel caries
• Therefore patients with low mutans streptococci population levels in their oral
cavity generally have low caries activity and patients with high mutans
streptococci population levels generally high caries activity
• Lactobacilli are the primary causative species of dentinal caries
PREVENTION OF DENTAL
CARIES
• Chlorhexidine is a very potent bactericidal agent
for streptococcus mutans, the most significant
group of bacterium associated with dental caries
• Chlorhexidine molecules adhere to the surfaces
of streptococcus mutans and produce cell death
• For patients with a high risk of caries,
chlorhexidine rinses can be successfully used to
reduce the number of odontopathogenic bacteria
WHAT MAKES CHX UNIQUE
• Its long lasting bacteriostatic action, also termed as
‘substantivity’
• Its action lasts for about 12 hours in the oral cavity after a
single rinse
• The di-cationic CHX molecule, attaches to the pellicle by one
cation, to the bacteria attempting to colonize the tooth surface
with the other. This is called the ‘Pin-Cushion Effect’
• This prolongs the CHX action
USES
1. As an adjunct to oral hygiene
2. Post oral surgery including periodontal surgery or root
planning
3. In patients with inter maxillary fixation.
4. For oral hygiene & gingival health in physically & mentally
handicapped
5. Medically compromised individuals predisposed to oral
infections
6. High caries risk patient
7. Recurrent oral ulceration
8. Removable & fixed orthodontic wearers
9. Treatment of denture stomatitis and dry socket
10. As an immediate prophylactic rinse in the prevention of postextraction bacteremia
ADVERSE EFFECTS
a)
b)
c)
d)
e)
f)
Extrinsic staining
Alteration in taste perception
Oral mucosal erosion
Enhanced supragingival calculus formation
Parotid gland swelling
Over dosage ingestion of 1 or 2 ounces of CHX oral rinse by
a small child might result in gastric distress, including nausea
or signs of alcohol intoxication
DOSES AND ADMINISTRATION
• Recommended use is twice daily oral rinsing for 30 seconds
after tooth brushing
• Usual dosage is 15ml (1 tablespoon) of undiluted
chlorhexidine oral rinse
• Patient should be instructed not to rinse with water or brush
teeth or eat immediately after CHX oral rinse
• CHX should not be ingested and should be expectorated after
rinsing
AVAILABLE
FORMULATIONS
• Mouth rinse- aqueous/ alcohol solutions of 0.2% [Zordyl
,Clorasept]
• Gel [corsodyl dental gel]
• Sprays [Hibispray]
• Tooth pastes
• Varnishes
• Chewing gums
• Periodontal dressings
• Subgingival plaque control [Periochip]
THANK YOU
Slide 11
CHLORHEXIDINE
Dr. Shahzadi Tayyaba
Hashmi
[email protected]
CHLORHEXIDINE
GLUCONATE
• Chlorhexidine gluconate is an effective
bactericidal agent and broad-spectrum
antimicrobial drug
• It has been extensively researched and is the
“gold standard” antimicrobial in oral hygiene
• Chlorhexidine is useful in many clinical
disciplines including periodontics, endodontics,
oral surgery and operative dentistry
INTRODUCTION
• Chlorhexidine is a broad-spectrum antimicrobial drug
• Acting as an antiseptic, it is an effective bactericidal
agent against all categories of microbes, including
bacteria, yeast and viruses
• Chlorhexidine was first used as a mouth rinse as an
adjunct to conventional non-surgical periodontal
therapy
• Chlorhexidine has proven efficacy as a broad-spectrum
antimicrobial for reducing supragingival plaque
PREVENTION OF DENTAL
CARIES
• There are a number of theories concerning the development and progression of
dental caries
• According to the specific Plaque hypothesis, only a limited number of bacteria
found in dental plaque can produce dental caries
• The most prominent among these bacteria are streptococcus mutans and
Lactobacilli
• Streptococcus mutans represent a group of closely related bacterial species that
are the primary species that initiate enamel caries
• Therefore patients with low mutans streptococci population levels in their oral
cavity generally have low caries activity and patients with high mutans
streptococci population levels generally high caries activity
• Lactobacilli are the primary causative species of dentinal caries
PREVENTION OF DENTAL
CARIES
• Chlorhexidine is a very potent bactericidal agent
for streptococcus mutans, the most significant
group of bacterium associated with dental caries
• Chlorhexidine molecules adhere to the surfaces
of streptococcus mutans and produce cell death
• For patients with a high risk of caries,
chlorhexidine rinses can be successfully used to
reduce the number of odontopathogenic bacteria
WHAT MAKES CHX UNIQUE
• Its long lasting bacteriostatic action, also termed as
‘substantivity’
• Its action lasts for about 12 hours in the oral cavity after a
single rinse
• The di-cationic CHX molecule, attaches to the pellicle by one
cation, to the bacteria attempting to colonize the tooth surface
with the other. This is called the ‘Pin-Cushion Effect’
• This prolongs the CHX action
USES
1. As an adjunct to oral hygiene
2. Post oral surgery including periodontal surgery or root
planning
3. In patients with inter maxillary fixation.
4. For oral hygiene & gingival health in physically & mentally
handicapped
5. Medically compromised individuals predisposed to oral
infections
6. High caries risk patient
7. Recurrent oral ulceration
8. Removable & fixed orthodontic wearers
9. Treatment of denture stomatitis and dry socket
10. As an immediate prophylactic rinse in the prevention of postextraction bacteremia
ADVERSE EFFECTS
a)
b)
c)
d)
e)
f)
Extrinsic staining
Alteration in taste perception
Oral mucosal erosion
Enhanced supragingival calculus formation
Parotid gland swelling
Over dosage ingestion of 1 or 2 ounces of CHX oral rinse by
a small child might result in gastric distress, including nausea
or signs of alcohol intoxication
DOSES AND ADMINISTRATION
• Recommended use is twice daily oral rinsing for 30 seconds
after tooth brushing
• Usual dosage is 15ml (1 tablespoon) of undiluted
chlorhexidine oral rinse
• Patient should be instructed not to rinse with water or brush
teeth or eat immediately after CHX oral rinse
• CHX should not be ingested and should be expectorated after
rinsing
AVAILABLE
FORMULATIONS
• Mouth rinse- aqueous/ alcohol solutions of 0.2% [Zordyl
,Clorasept]
• Gel [corsodyl dental gel]
• Sprays [Hibispray]
• Tooth pastes
• Varnishes
• Chewing gums
• Periodontal dressings
• Subgingival plaque control [Periochip]
THANK YOU
CHLORHEXIDINE
Dr. Shahzadi Tayyaba
Hashmi
[email protected]
CHLORHEXIDINE
GLUCONATE
• Chlorhexidine gluconate is an effective
bactericidal agent and broad-spectrum
antimicrobial drug
• It has been extensively researched and is the
“gold standard” antimicrobial in oral hygiene
• Chlorhexidine is useful in many clinical
disciplines including periodontics, endodontics,
oral surgery and operative dentistry
INTRODUCTION
• Chlorhexidine is a broad-spectrum antimicrobial drug
• Acting as an antiseptic, it is an effective bactericidal
agent against all categories of microbes, including
bacteria, yeast and viruses
• Chlorhexidine was first used as a mouth rinse as an
adjunct to conventional non-surgical periodontal
therapy
• Chlorhexidine has proven efficacy as a broad-spectrum
antimicrobial for reducing supragingival plaque
PREVENTION OF DENTAL
CARIES
• There are a number of theories concerning the development and progression of
dental caries
• According to the specific Plaque hypothesis, only a limited number of bacteria
found in dental plaque can produce dental caries
• The most prominent among these bacteria are streptococcus mutans and
Lactobacilli
• Streptococcus mutans represent a group of closely related bacterial species that
are the primary species that initiate enamel caries
• Therefore patients with low mutans streptococci population levels in their oral
cavity generally have low caries activity and patients with high mutans
streptococci population levels generally high caries activity
• Lactobacilli are the primary causative species of dentinal caries
PREVENTION OF DENTAL
CARIES
• Chlorhexidine is a very potent bactericidal agent
for streptococcus mutans, the most significant
group of bacterium associated with dental caries
• Chlorhexidine molecules adhere to the surfaces
of streptococcus mutans and produce cell death
• For patients with a high risk of caries,
chlorhexidine rinses can be successfully used to
reduce the number of odontopathogenic bacteria
WHAT MAKES CHX UNIQUE
• Its long lasting bacteriostatic action, also termed as
‘substantivity’
• Its action lasts for about 12 hours in the oral cavity after a
single rinse
• The di-cationic CHX molecule, attaches to the pellicle by one
cation, to the bacteria attempting to colonize the tooth surface
with the other. This is called the ‘Pin-Cushion Effect’
• This prolongs the CHX action
USES
1. As an adjunct to oral hygiene
2. Post oral surgery including periodontal surgery or root
planning
3. In patients with inter maxillary fixation.
4. For oral hygiene & gingival health in physically & mentally
handicapped
5. Medically compromised individuals predisposed to oral
infections
6. High caries risk patient
7. Recurrent oral ulceration
8. Removable & fixed orthodontic wearers
9. Treatment of denture stomatitis and dry socket
10. As an immediate prophylactic rinse in the prevention of postextraction bacteremia
ADVERSE EFFECTS
a)
b)
c)
d)
e)
f)
Extrinsic staining
Alteration in taste perception
Oral mucosal erosion
Enhanced supragingival calculus formation
Parotid gland swelling
Over dosage ingestion of 1 or 2 ounces of CHX oral rinse by
a small child might result in gastric distress, including nausea
or signs of alcohol intoxication
DOSES AND ADMINISTRATION
• Recommended use is twice daily oral rinsing for 30 seconds
after tooth brushing
• Usual dosage is 15ml (1 tablespoon) of undiluted
chlorhexidine oral rinse
• Patient should be instructed not to rinse with water or brush
teeth or eat immediately after CHX oral rinse
• CHX should not be ingested and should be expectorated after
rinsing
AVAILABLE
FORMULATIONS
• Mouth rinse- aqueous/ alcohol solutions of 0.2% [Zordyl
,Clorasept]
• Gel [corsodyl dental gel]
• Sprays [Hibispray]
• Tooth pastes
• Varnishes
• Chewing gums
• Periodontal dressings
• Subgingival plaque control [Periochip]
THANK YOU
Slide 2
CHLORHEXIDINE
Dr. Shahzadi Tayyaba
Hashmi
[email protected]
CHLORHEXIDINE
GLUCONATE
• Chlorhexidine gluconate is an effective
bactericidal agent and broad-spectrum
antimicrobial drug
• It has been extensively researched and is the
“gold standard” antimicrobial in oral hygiene
• Chlorhexidine is useful in many clinical
disciplines including periodontics, endodontics,
oral surgery and operative dentistry
INTRODUCTION
• Chlorhexidine is a broad-spectrum antimicrobial drug
• Acting as an antiseptic, it is an effective bactericidal
agent against all categories of microbes, including
bacteria, yeast and viruses
• Chlorhexidine was first used as a mouth rinse as an
adjunct to conventional non-surgical periodontal
therapy
• Chlorhexidine has proven efficacy as a broad-spectrum
antimicrobial for reducing supragingival plaque
PREVENTION OF DENTAL
CARIES
• There are a number of theories concerning the development and progression of
dental caries
• According to the specific Plaque hypothesis, only a limited number of bacteria
found in dental plaque can produce dental caries
• The most prominent among these bacteria are streptococcus mutans and
Lactobacilli
• Streptococcus mutans represent a group of closely related bacterial species that
are the primary species that initiate enamel caries
• Therefore patients with low mutans streptococci population levels in their oral
cavity generally have low caries activity and patients with high mutans
streptococci population levels generally high caries activity
• Lactobacilli are the primary causative species of dentinal caries
PREVENTION OF DENTAL
CARIES
• Chlorhexidine is a very potent bactericidal agent
for streptococcus mutans, the most significant
group of bacterium associated with dental caries
• Chlorhexidine molecules adhere to the surfaces
of streptococcus mutans and produce cell death
• For patients with a high risk of caries,
chlorhexidine rinses can be successfully used to
reduce the number of odontopathogenic bacteria
WHAT MAKES CHX UNIQUE
• Its long lasting bacteriostatic action, also termed as
‘substantivity’
• Its action lasts for about 12 hours in the oral cavity after a
single rinse
• The di-cationic CHX molecule, attaches to the pellicle by one
cation, to the bacteria attempting to colonize the tooth surface
with the other. This is called the ‘Pin-Cushion Effect’
• This prolongs the CHX action
USES
1. As an adjunct to oral hygiene
2. Post oral surgery including periodontal surgery or root
planning
3. In patients with inter maxillary fixation.
4. For oral hygiene & gingival health in physically & mentally
handicapped
5. Medically compromised individuals predisposed to oral
infections
6. High caries risk patient
7. Recurrent oral ulceration
8. Removable & fixed orthodontic wearers
9. Treatment of denture stomatitis and dry socket
10. As an immediate prophylactic rinse in the prevention of postextraction bacteremia
ADVERSE EFFECTS
a)
b)
c)
d)
e)
f)
Extrinsic staining
Alteration in taste perception
Oral mucosal erosion
Enhanced supragingival calculus formation
Parotid gland swelling
Over dosage ingestion of 1 or 2 ounces of CHX oral rinse by
a small child might result in gastric distress, including nausea
or signs of alcohol intoxication
DOSES AND ADMINISTRATION
• Recommended use is twice daily oral rinsing for 30 seconds
after tooth brushing
• Usual dosage is 15ml (1 tablespoon) of undiluted
chlorhexidine oral rinse
• Patient should be instructed not to rinse with water or brush
teeth or eat immediately after CHX oral rinse
• CHX should not be ingested and should be expectorated after
rinsing
AVAILABLE
FORMULATIONS
• Mouth rinse- aqueous/ alcohol solutions of 0.2% [Zordyl
,Clorasept]
• Gel [corsodyl dental gel]
• Sprays [Hibispray]
• Tooth pastes
• Varnishes
• Chewing gums
• Periodontal dressings
• Subgingival plaque control [Periochip]
THANK YOU
Slide 3
CHLORHEXIDINE
Dr. Shahzadi Tayyaba
Hashmi
[email protected]
CHLORHEXIDINE
GLUCONATE
• Chlorhexidine gluconate is an effective
bactericidal agent and broad-spectrum
antimicrobial drug
• It has been extensively researched and is the
“gold standard” antimicrobial in oral hygiene
• Chlorhexidine is useful in many clinical
disciplines including periodontics, endodontics,
oral surgery and operative dentistry
INTRODUCTION
• Chlorhexidine is a broad-spectrum antimicrobial drug
• Acting as an antiseptic, it is an effective bactericidal
agent against all categories of microbes, including
bacteria, yeast and viruses
• Chlorhexidine was first used as a mouth rinse as an
adjunct to conventional non-surgical periodontal
therapy
• Chlorhexidine has proven efficacy as a broad-spectrum
antimicrobial for reducing supragingival plaque
PREVENTION OF DENTAL
CARIES
• There are a number of theories concerning the development and progression of
dental caries
• According to the specific Plaque hypothesis, only a limited number of bacteria
found in dental plaque can produce dental caries
• The most prominent among these bacteria are streptococcus mutans and
Lactobacilli
• Streptococcus mutans represent a group of closely related bacterial species that
are the primary species that initiate enamel caries
• Therefore patients with low mutans streptococci population levels in their oral
cavity generally have low caries activity and patients with high mutans
streptococci population levels generally high caries activity
• Lactobacilli are the primary causative species of dentinal caries
PREVENTION OF DENTAL
CARIES
• Chlorhexidine is a very potent bactericidal agent
for streptococcus mutans, the most significant
group of bacterium associated with dental caries
• Chlorhexidine molecules adhere to the surfaces
of streptococcus mutans and produce cell death
• For patients with a high risk of caries,
chlorhexidine rinses can be successfully used to
reduce the number of odontopathogenic bacteria
WHAT MAKES CHX UNIQUE
• Its long lasting bacteriostatic action, also termed as
‘substantivity’
• Its action lasts for about 12 hours in the oral cavity after a
single rinse
• The di-cationic CHX molecule, attaches to the pellicle by one
cation, to the bacteria attempting to colonize the tooth surface
with the other. This is called the ‘Pin-Cushion Effect’
• This prolongs the CHX action
USES
1. As an adjunct to oral hygiene
2. Post oral surgery including periodontal surgery or root
planning
3. In patients with inter maxillary fixation.
4. For oral hygiene & gingival health in physically & mentally
handicapped
5. Medically compromised individuals predisposed to oral
infections
6. High caries risk patient
7. Recurrent oral ulceration
8. Removable & fixed orthodontic wearers
9. Treatment of denture stomatitis and dry socket
10. As an immediate prophylactic rinse in the prevention of postextraction bacteremia
ADVERSE EFFECTS
a)
b)
c)
d)
e)
f)
Extrinsic staining
Alteration in taste perception
Oral mucosal erosion
Enhanced supragingival calculus formation
Parotid gland swelling
Over dosage ingestion of 1 or 2 ounces of CHX oral rinse by
a small child might result in gastric distress, including nausea
or signs of alcohol intoxication
DOSES AND ADMINISTRATION
• Recommended use is twice daily oral rinsing for 30 seconds
after tooth brushing
• Usual dosage is 15ml (1 tablespoon) of undiluted
chlorhexidine oral rinse
• Patient should be instructed not to rinse with water or brush
teeth or eat immediately after CHX oral rinse
• CHX should not be ingested and should be expectorated after
rinsing
AVAILABLE
FORMULATIONS
• Mouth rinse- aqueous/ alcohol solutions of 0.2% [Zordyl
,Clorasept]
• Gel [corsodyl dental gel]
• Sprays [Hibispray]
• Tooth pastes
• Varnishes
• Chewing gums
• Periodontal dressings
• Subgingival plaque control [Periochip]
THANK YOU
Slide 4
CHLORHEXIDINE
Dr. Shahzadi Tayyaba
Hashmi
[email protected]
CHLORHEXIDINE
GLUCONATE
• Chlorhexidine gluconate is an effective
bactericidal agent and broad-spectrum
antimicrobial drug
• It has been extensively researched and is the
“gold standard” antimicrobial in oral hygiene
• Chlorhexidine is useful in many clinical
disciplines including periodontics, endodontics,
oral surgery and operative dentistry
INTRODUCTION
• Chlorhexidine is a broad-spectrum antimicrobial drug
• Acting as an antiseptic, it is an effective bactericidal
agent against all categories of microbes, including
bacteria, yeast and viruses
• Chlorhexidine was first used as a mouth rinse as an
adjunct to conventional non-surgical periodontal
therapy
• Chlorhexidine has proven efficacy as a broad-spectrum
antimicrobial for reducing supragingival plaque
PREVENTION OF DENTAL
CARIES
• There are a number of theories concerning the development and progression of
dental caries
• According to the specific Plaque hypothesis, only a limited number of bacteria
found in dental plaque can produce dental caries
• The most prominent among these bacteria are streptococcus mutans and
Lactobacilli
• Streptococcus mutans represent a group of closely related bacterial species that
are the primary species that initiate enamel caries
• Therefore patients with low mutans streptococci population levels in their oral
cavity generally have low caries activity and patients with high mutans
streptococci population levels generally high caries activity
• Lactobacilli are the primary causative species of dentinal caries
PREVENTION OF DENTAL
CARIES
• Chlorhexidine is a very potent bactericidal agent
for streptococcus mutans, the most significant
group of bacterium associated with dental caries
• Chlorhexidine molecules adhere to the surfaces
of streptococcus mutans and produce cell death
• For patients with a high risk of caries,
chlorhexidine rinses can be successfully used to
reduce the number of odontopathogenic bacteria
WHAT MAKES CHX UNIQUE
• Its long lasting bacteriostatic action, also termed as
‘substantivity’
• Its action lasts for about 12 hours in the oral cavity after a
single rinse
• The di-cationic CHX molecule, attaches to the pellicle by one
cation, to the bacteria attempting to colonize the tooth surface
with the other. This is called the ‘Pin-Cushion Effect’
• This prolongs the CHX action
USES
1. As an adjunct to oral hygiene
2. Post oral surgery including periodontal surgery or root
planning
3. In patients with inter maxillary fixation.
4. For oral hygiene & gingival health in physically & mentally
handicapped
5. Medically compromised individuals predisposed to oral
infections
6. High caries risk patient
7. Recurrent oral ulceration
8. Removable & fixed orthodontic wearers
9. Treatment of denture stomatitis and dry socket
10. As an immediate prophylactic rinse in the prevention of postextraction bacteremia
ADVERSE EFFECTS
a)
b)
c)
d)
e)
f)
Extrinsic staining
Alteration in taste perception
Oral mucosal erosion
Enhanced supragingival calculus formation
Parotid gland swelling
Over dosage ingestion of 1 or 2 ounces of CHX oral rinse by
a small child might result in gastric distress, including nausea
or signs of alcohol intoxication
DOSES AND ADMINISTRATION
• Recommended use is twice daily oral rinsing for 30 seconds
after tooth brushing
• Usual dosage is 15ml (1 tablespoon) of undiluted
chlorhexidine oral rinse
• Patient should be instructed not to rinse with water or brush
teeth or eat immediately after CHX oral rinse
• CHX should not be ingested and should be expectorated after
rinsing
AVAILABLE
FORMULATIONS
• Mouth rinse- aqueous/ alcohol solutions of 0.2% [Zordyl
,Clorasept]
• Gel [corsodyl dental gel]
• Sprays [Hibispray]
• Tooth pastes
• Varnishes
• Chewing gums
• Periodontal dressings
• Subgingival plaque control [Periochip]
THANK YOU
Slide 5
CHLORHEXIDINE
Dr. Shahzadi Tayyaba
Hashmi
[email protected]
CHLORHEXIDINE
GLUCONATE
• Chlorhexidine gluconate is an effective
bactericidal agent and broad-spectrum
antimicrobial drug
• It has been extensively researched and is the
“gold standard” antimicrobial in oral hygiene
• Chlorhexidine is useful in many clinical
disciplines including periodontics, endodontics,
oral surgery and operative dentistry
INTRODUCTION
• Chlorhexidine is a broad-spectrum antimicrobial drug
• Acting as an antiseptic, it is an effective bactericidal
agent against all categories of microbes, including
bacteria, yeast and viruses
• Chlorhexidine was first used as a mouth rinse as an
adjunct to conventional non-surgical periodontal
therapy
• Chlorhexidine has proven efficacy as a broad-spectrum
antimicrobial for reducing supragingival plaque
PREVENTION OF DENTAL
CARIES
• There are a number of theories concerning the development and progression of
dental caries
• According to the specific Plaque hypothesis, only a limited number of bacteria
found in dental plaque can produce dental caries
• The most prominent among these bacteria are streptococcus mutans and
Lactobacilli
• Streptococcus mutans represent a group of closely related bacterial species that
are the primary species that initiate enamel caries
• Therefore patients with low mutans streptococci population levels in their oral
cavity generally have low caries activity and patients with high mutans
streptococci population levels generally high caries activity
• Lactobacilli are the primary causative species of dentinal caries
PREVENTION OF DENTAL
CARIES
• Chlorhexidine is a very potent bactericidal agent
for streptococcus mutans, the most significant
group of bacterium associated with dental caries
• Chlorhexidine molecules adhere to the surfaces
of streptococcus mutans and produce cell death
• For patients with a high risk of caries,
chlorhexidine rinses can be successfully used to
reduce the number of odontopathogenic bacteria
WHAT MAKES CHX UNIQUE
• Its long lasting bacteriostatic action, also termed as
‘substantivity’
• Its action lasts for about 12 hours in the oral cavity after a
single rinse
• The di-cationic CHX molecule, attaches to the pellicle by one
cation, to the bacteria attempting to colonize the tooth surface
with the other. This is called the ‘Pin-Cushion Effect’
• This prolongs the CHX action
USES
1. As an adjunct to oral hygiene
2. Post oral surgery including periodontal surgery or root
planning
3. In patients with inter maxillary fixation.
4. For oral hygiene & gingival health in physically & mentally
handicapped
5. Medically compromised individuals predisposed to oral
infections
6. High caries risk patient
7. Recurrent oral ulceration
8. Removable & fixed orthodontic wearers
9. Treatment of denture stomatitis and dry socket
10. As an immediate prophylactic rinse in the prevention of postextraction bacteremia
ADVERSE EFFECTS
a)
b)
c)
d)
e)
f)
Extrinsic staining
Alteration in taste perception
Oral mucosal erosion
Enhanced supragingival calculus formation
Parotid gland swelling
Over dosage ingestion of 1 or 2 ounces of CHX oral rinse by
a small child might result in gastric distress, including nausea
or signs of alcohol intoxication
DOSES AND ADMINISTRATION
• Recommended use is twice daily oral rinsing for 30 seconds
after tooth brushing
• Usual dosage is 15ml (1 tablespoon) of undiluted
chlorhexidine oral rinse
• Patient should be instructed not to rinse with water or brush
teeth or eat immediately after CHX oral rinse
• CHX should not be ingested and should be expectorated after
rinsing
AVAILABLE
FORMULATIONS
• Mouth rinse- aqueous/ alcohol solutions of 0.2% [Zordyl
,Clorasept]
• Gel [corsodyl dental gel]
• Sprays [Hibispray]
• Tooth pastes
• Varnishes
• Chewing gums
• Periodontal dressings
• Subgingival plaque control [Periochip]
THANK YOU
Slide 6
CHLORHEXIDINE
Dr. Shahzadi Tayyaba
Hashmi
[email protected]
CHLORHEXIDINE
GLUCONATE
• Chlorhexidine gluconate is an effective
bactericidal agent and broad-spectrum
antimicrobial drug
• It has been extensively researched and is the
“gold standard” antimicrobial in oral hygiene
• Chlorhexidine is useful in many clinical
disciplines including periodontics, endodontics,
oral surgery and operative dentistry
INTRODUCTION
• Chlorhexidine is a broad-spectrum antimicrobial drug
• Acting as an antiseptic, it is an effective bactericidal
agent against all categories of microbes, including
bacteria, yeast and viruses
• Chlorhexidine was first used as a mouth rinse as an
adjunct to conventional non-surgical periodontal
therapy
• Chlorhexidine has proven efficacy as a broad-spectrum
antimicrobial for reducing supragingival plaque
PREVENTION OF DENTAL
CARIES
• There are a number of theories concerning the development and progression of
dental caries
• According to the specific Plaque hypothesis, only a limited number of bacteria
found in dental plaque can produce dental caries
• The most prominent among these bacteria are streptococcus mutans and
Lactobacilli
• Streptococcus mutans represent a group of closely related bacterial species that
are the primary species that initiate enamel caries
• Therefore patients with low mutans streptococci population levels in their oral
cavity generally have low caries activity and patients with high mutans
streptococci population levels generally high caries activity
• Lactobacilli are the primary causative species of dentinal caries
PREVENTION OF DENTAL
CARIES
• Chlorhexidine is a very potent bactericidal agent
for streptococcus mutans, the most significant
group of bacterium associated with dental caries
• Chlorhexidine molecules adhere to the surfaces
of streptococcus mutans and produce cell death
• For patients with a high risk of caries,
chlorhexidine rinses can be successfully used to
reduce the number of odontopathogenic bacteria
WHAT MAKES CHX UNIQUE
• Its long lasting bacteriostatic action, also termed as
‘substantivity’
• Its action lasts for about 12 hours in the oral cavity after a
single rinse
• The di-cationic CHX molecule, attaches to the pellicle by one
cation, to the bacteria attempting to colonize the tooth surface
with the other. This is called the ‘Pin-Cushion Effect’
• This prolongs the CHX action
USES
1. As an adjunct to oral hygiene
2. Post oral surgery including periodontal surgery or root
planning
3. In patients with inter maxillary fixation.
4. For oral hygiene & gingival health in physically & mentally
handicapped
5. Medically compromised individuals predisposed to oral
infections
6. High caries risk patient
7. Recurrent oral ulceration
8. Removable & fixed orthodontic wearers
9. Treatment of denture stomatitis and dry socket
10. As an immediate prophylactic rinse in the prevention of postextraction bacteremia
ADVERSE EFFECTS
a)
b)
c)
d)
e)
f)
Extrinsic staining
Alteration in taste perception
Oral mucosal erosion
Enhanced supragingival calculus formation
Parotid gland swelling
Over dosage ingestion of 1 or 2 ounces of CHX oral rinse by
a small child might result in gastric distress, including nausea
or signs of alcohol intoxication
DOSES AND ADMINISTRATION
• Recommended use is twice daily oral rinsing for 30 seconds
after tooth brushing
• Usual dosage is 15ml (1 tablespoon) of undiluted
chlorhexidine oral rinse
• Patient should be instructed not to rinse with water or brush
teeth or eat immediately after CHX oral rinse
• CHX should not be ingested and should be expectorated after
rinsing
AVAILABLE
FORMULATIONS
• Mouth rinse- aqueous/ alcohol solutions of 0.2% [Zordyl
,Clorasept]
• Gel [corsodyl dental gel]
• Sprays [Hibispray]
• Tooth pastes
• Varnishes
• Chewing gums
• Periodontal dressings
• Subgingival plaque control [Periochip]
THANK YOU
Slide 7
CHLORHEXIDINE
Dr. Shahzadi Tayyaba
Hashmi
[email protected]
CHLORHEXIDINE
GLUCONATE
• Chlorhexidine gluconate is an effective
bactericidal agent and broad-spectrum
antimicrobial drug
• It has been extensively researched and is the
“gold standard” antimicrobial in oral hygiene
• Chlorhexidine is useful in many clinical
disciplines including periodontics, endodontics,
oral surgery and operative dentistry
INTRODUCTION
• Chlorhexidine is a broad-spectrum antimicrobial drug
• Acting as an antiseptic, it is an effective bactericidal
agent against all categories of microbes, including
bacteria, yeast and viruses
• Chlorhexidine was first used as a mouth rinse as an
adjunct to conventional non-surgical periodontal
therapy
• Chlorhexidine has proven efficacy as a broad-spectrum
antimicrobial for reducing supragingival plaque
PREVENTION OF DENTAL
CARIES
• There are a number of theories concerning the development and progression of
dental caries
• According to the specific Plaque hypothesis, only a limited number of bacteria
found in dental plaque can produce dental caries
• The most prominent among these bacteria are streptococcus mutans and
Lactobacilli
• Streptococcus mutans represent a group of closely related bacterial species that
are the primary species that initiate enamel caries
• Therefore patients with low mutans streptococci population levels in their oral
cavity generally have low caries activity and patients with high mutans
streptococci population levels generally high caries activity
• Lactobacilli are the primary causative species of dentinal caries
PREVENTION OF DENTAL
CARIES
• Chlorhexidine is a very potent bactericidal agent
for streptococcus mutans, the most significant
group of bacterium associated with dental caries
• Chlorhexidine molecules adhere to the surfaces
of streptococcus mutans and produce cell death
• For patients with a high risk of caries,
chlorhexidine rinses can be successfully used to
reduce the number of odontopathogenic bacteria
WHAT MAKES CHX UNIQUE
• Its long lasting bacteriostatic action, also termed as
‘substantivity’
• Its action lasts for about 12 hours in the oral cavity after a
single rinse
• The di-cationic CHX molecule, attaches to the pellicle by one
cation, to the bacteria attempting to colonize the tooth surface
with the other. This is called the ‘Pin-Cushion Effect’
• This prolongs the CHX action
USES
1. As an adjunct to oral hygiene
2. Post oral surgery including periodontal surgery or root
planning
3. In patients with inter maxillary fixation.
4. For oral hygiene & gingival health in physically & mentally
handicapped
5. Medically compromised individuals predisposed to oral
infections
6. High caries risk patient
7. Recurrent oral ulceration
8. Removable & fixed orthodontic wearers
9. Treatment of denture stomatitis and dry socket
10. As an immediate prophylactic rinse in the prevention of postextraction bacteremia
ADVERSE EFFECTS
a)
b)
c)
d)
e)
f)
Extrinsic staining
Alteration in taste perception
Oral mucosal erosion
Enhanced supragingival calculus formation
Parotid gland swelling
Over dosage ingestion of 1 or 2 ounces of CHX oral rinse by
a small child might result in gastric distress, including nausea
or signs of alcohol intoxication
DOSES AND ADMINISTRATION
• Recommended use is twice daily oral rinsing for 30 seconds
after tooth brushing
• Usual dosage is 15ml (1 tablespoon) of undiluted
chlorhexidine oral rinse
• Patient should be instructed not to rinse with water or brush
teeth or eat immediately after CHX oral rinse
• CHX should not be ingested and should be expectorated after
rinsing
AVAILABLE
FORMULATIONS
• Mouth rinse- aqueous/ alcohol solutions of 0.2% [Zordyl
,Clorasept]
• Gel [corsodyl dental gel]
• Sprays [Hibispray]
• Tooth pastes
• Varnishes
• Chewing gums
• Periodontal dressings
• Subgingival plaque control [Periochip]
THANK YOU
Slide 8
CHLORHEXIDINE
Dr. Shahzadi Tayyaba
Hashmi
[email protected]
CHLORHEXIDINE
GLUCONATE
• Chlorhexidine gluconate is an effective
bactericidal agent and broad-spectrum
antimicrobial drug
• It has been extensively researched and is the
“gold standard” antimicrobial in oral hygiene
• Chlorhexidine is useful in many clinical
disciplines including periodontics, endodontics,
oral surgery and operative dentistry
INTRODUCTION
• Chlorhexidine is a broad-spectrum antimicrobial drug
• Acting as an antiseptic, it is an effective bactericidal
agent against all categories of microbes, including
bacteria, yeast and viruses
• Chlorhexidine was first used as a mouth rinse as an
adjunct to conventional non-surgical periodontal
therapy
• Chlorhexidine has proven efficacy as a broad-spectrum
antimicrobial for reducing supragingival plaque
PREVENTION OF DENTAL
CARIES
• There are a number of theories concerning the development and progression of
dental caries
• According to the specific Plaque hypothesis, only a limited number of bacteria
found in dental plaque can produce dental caries
• The most prominent among these bacteria are streptococcus mutans and
Lactobacilli
• Streptococcus mutans represent a group of closely related bacterial species that
are the primary species that initiate enamel caries
• Therefore patients with low mutans streptococci population levels in their oral
cavity generally have low caries activity and patients with high mutans
streptococci population levels generally high caries activity
• Lactobacilli are the primary causative species of dentinal caries
PREVENTION OF DENTAL
CARIES
• Chlorhexidine is a very potent bactericidal agent
for streptococcus mutans, the most significant
group of bacterium associated with dental caries
• Chlorhexidine molecules adhere to the surfaces
of streptococcus mutans and produce cell death
• For patients with a high risk of caries,
chlorhexidine rinses can be successfully used to
reduce the number of odontopathogenic bacteria
WHAT MAKES CHX UNIQUE
• Its long lasting bacteriostatic action, also termed as
‘substantivity’
• Its action lasts for about 12 hours in the oral cavity after a
single rinse
• The di-cationic CHX molecule, attaches to the pellicle by one
cation, to the bacteria attempting to colonize the tooth surface
with the other. This is called the ‘Pin-Cushion Effect’
• This prolongs the CHX action
USES
1. As an adjunct to oral hygiene
2. Post oral surgery including periodontal surgery or root
planning
3. In patients with inter maxillary fixation.
4. For oral hygiene & gingival health in physically & mentally
handicapped
5. Medically compromised individuals predisposed to oral
infections
6. High caries risk patient
7. Recurrent oral ulceration
8. Removable & fixed orthodontic wearers
9. Treatment of denture stomatitis and dry socket
10. As an immediate prophylactic rinse in the prevention of postextraction bacteremia
ADVERSE EFFECTS
a)
b)
c)
d)
e)
f)
Extrinsic staining
Alteration in taste perception
Oral mucosal erosion
Enhanced supragingival calculus formation
Parotid gland swelling
Over dosage ingestion of 1 or 2 ounces of CHX oral rinse by
a small child might result in gastric distress, including nausea
or signs of alcohol intoxication
DOSES AND ADMINISTRATION
• Recommended use is twice daily oral rinsing for 30 seconds
after tooth brushing
• Usual dosage is 15ml (1 tablespoon) of undiluted
chlorhexidine oral rinse
• Patient should be instructed not to rinse with water or brush
teeth or eat immediately after CHX oral rinse
• CHX should not be ingested and should be expectorated after
rinsing
AVAILABLE
FORMULATIONS
• Mouth rinse- aqueous/ alcohol solutions of 0.2% [Zordyl
,Clorasept]
• Gel [corsodyl dental gel]
• Sprays [Hibispray]
• Tooth pastes
• Varnishes
• Chewing gums
• Periodontal dressings
• Subgingival plaque control [Periochip]
THANK YOU
Slide 9
CHLORHEXIDINE
Dr. Shahzadi Tayyaba
Hashmi
[email protected]
CHLORHEXIDINE
GLUCONATE
• Chlorhexidine gluconate is an effective
bactericidal agent and broad-spectrum
antimicrobial drug
• It has been extensively researched and is the
“gold standard” antimicrobial in oral hygiene
• Chlorhexidine is useful in many clinical
disciplines including periodontics, endodontics,
oral surgery and operative dentistry
INTRODUCTION
• Chlorhexidine is a broad-spectrum antimicrobial drug
• Acting as an antiseptic, it is an effective bactericidal
agent against all categories of microbes, including
bacteria, yeast and viruses
• Chlorhexidine was first used as a mouth rinse as an
adjunct to conventional non-surgical periodontal
therapy
• Chlorhexidine has proven efficacy as a broad-spectrum
antimicrobial for reducing supragingival plaque
PREVENTION OF DENTAL
CARIES
• There are a number of theories concerning the development and progression of
dental caries
• According to the specific Plaque hypothesis, only a limited number of bacteria
found in dental plaque can produce dental caries
• The most prominent among these bacteria are streptococcus mutans and
Lactobacilli
• Streptococcus mutans represent a group of closely related bacterial species that
are the primary species that initiate enamel caries
• Therefore patients with low mutans streptococci population levels in their oral
cavity generally have low caries activity and patients with high mutans
streptococci population levels generally high caries activity
• Lactobacilli are the primary causative species of dentinal caries
PREVENTION OF DENTAL
CARIES
• Chlorhexidine is a very potent bactericidal agent
for streptococcus mutans, the most significant
group of bacterium associated with dental caries
• Chlorhexidine molecules adhere to the surfaces
of streptococcus mutans and produce cell death
• For patients with a high risk of caries,
chlorhexidine rinses can be successfully used to
reduce the number of odontopathogenic bacteria
WHAT MAKES CHX UNIQUE
• Its long lasting bacteriostatic action, also termed as
‘substantivity’
• Its action lasts for about 12 hours in the oral cavity after a
single rinse
• The di-cationic CHX molecule, attaches to the pellicle by one
cation, to the bacteria attempting to colonize the tooth surface
with the other. This is called the ‘Pin-Cushion Effect’
• This prolongs the CHX action
USES
1. As an adjunct to oral hygiene
2. Post oral surgery including periodontal surgery or root
planning
3. In patients with inter maxillary fixation.
4. For oral hygiene & gingival health in physically & mentally
handicapped
5. Medically compromised individuals predisposed to oral
infections
6. High caries risk patient
7. Recurrent oral ulceration
8. Removable & fixed orthodontic wearers
9. Treatment of denture stomatitis and dry socket
10. As an immediate prophylactic rinse in the prevention of postextraction bacteremia
ADVERSE EFFECTS
a)
b)
c)
d)
e)
f)
Extrinsic staining
Alteration in taste perception
Oral mucosal erosion
Enhanced supragingival calculus formation
Parotid gland swelling
Over dosage ingestion of 1 or 2 ounces of CHX oral rinse by
a small child might result in gastric distress, including nausea
or signs of alcohol intoxication
DOSES AND ADMINISTRATION
• Recommended use is twice daily oral rinsing for 30 seconds
after tooth brushing
• Usual dosage is 15ml (1 tablespoon) of undiluted
chlorhexidine oral rinse
• Patient should be instructed not to rinse with water or brush
teeth or eat immediately after CHX oral rinse
• CHX should not be ingested and should be expectorated after
rinsing
AVAILABLE
FORMULATIONS
• Mouth rinse- aqueous/ alcohol solutions of 0.2% [Zordyl
,Clorasept]
• Gel [corsodyl dental gel]
• Sprays [Hibispray]
• Tooth pastes
• Varnishes
• Chewing gums
• Periodontal dressings
• Subgingival plaque control [Periochip]
THANK YOU
Slide 10
CHLORHEXIDINE
Dr. Shahzadi Tayyaba
Hashmi
[email protected]
CHLORHEXIDINE
GLUCONATE
• Chlorhexidine gluconate is an effective
bactericidal agent and broad-spectrum
antimicrobial drug
• It has been extensively researched and is the
“gold standard” antimicrobial in oral hygiene
• Chlorhexidine is useful in many clinical
disciplines including periodontics, endodontics,
oral surgery and operative dentistry
INTRODUCTION
• Chlorhexidine is a broad-spectrum antimicrobial drug
• Acting as an antiseptic, it is an effective bactericidal
agent against all categories of microbes, including
bacteria, yeast and viruses
• Chlorhexidine was first used as a mouth rinse as an
adjunct to conventional non-surgical periodontal
therapy
• Chlorhexidine has proven efficacy as a broad-spectrum
antimicrobial for reducing supragingival plaque
PREVENTION OF DENTAL
CARIES
• There are a number of theories concerning the development and progression of
dental caries
• According to the specific Plaque hypothesis, only a limited number of bacteria
found in dental plaque can produce dental caries
• The most prominent among these bacteria are streptococcus mutans and
Lactobacilli
• Streptococcus mutans represent a group of closely related bacterial species that
are the primary species that initiate enamel caries
• Therefore patients with low mutans streptococci population levels in their oral
cavity generally have low caries activity and patients with high mutans
streptococci population levels generally high caries activity
• Lactobacilli are the primary causative species of dentinal caries
PREVENTION OF DENTAL
CARIES
• Chlorhexidine is a very potent bactericidal agent
for streptococcus mutans, the most significant
group of bacterium associated with dental caries
• Chlorhexidine molecules adhere to the surfaces
of streptococcus mutans and produce cell death
• For patients with a high risk of caries,
chlorhexidine rinses can be successfully used to
reduce the number of odontopathogenic bacteria
WHAT MAKES CHX UNIQUE
• Its long lasting bacteriostatic action, also termed as
‘substantivity’
• Its action lasts for about 12 hours in the oral cavity after a
single rinse
• The di-cationic CHX molecule, attaches to the pellicle by one
cation, to the bacteria attempting to colonize the tooth surface
with the other. This is called the ‘Pin-Cushion Effect’
• This prolongs the CHX action
USES
1. As an adjunct to oral hygiene
2. Post oral surgery including periodontal surgery or root
planning
3. In patients with inter maxillary fixation.
4. For oral hygiene & gingival health in physically & mentally
handicapped
5. Medically compromised individuals predisposed to oral
infections
6. High caries risk patient
7. Recurrent oral ulceration
8. Removable & fixed orthodontic wearers
9. Treatment of denture stomatitis and dry socket
10. As an immediate prophylactic rinse in the prevention of postextraction bacteremia
ADVERSE EFFECTS
a)
b)
c)
d)
e)
f)
Extrinsic staining
Alteration in taste perception
Oral mucosal erosion
Enhanced supragingival calculus formation
Parotid gland swelling
Over dosage ingestion of 1 or 2 ounces of CHX oral rinse by
a small child might result in gastric distress, including nausea
or signs of alcohol intoxication
DOSES AND ADMINISTRATION
• Recommended use is twice daily oral rinsing for 30 seconds
after tooth brushing
• Usual dosage is 15ml (1 tablespoon) of undiluted
chlorhexidine oral rinse
• Patient should be instructed not to rinse with water or brush
teeth or eat immediately after CHX oral rinse
• CHX should not be ingested and should be expectorated after
rinsing
AVAILABLE
FORMULATIONS
• Mouth rinse- aqueous/ alcohol solutions of 0.2% [Zordyl
,Clorasept]
• Gel [corsodyl dental gel]
• Sprays [Hibispray]
• Tooth pastes
• Varnishes
• Chewing gums
• Periodontal dressings
• Subgingival plaque control [Periochip]
THANK YOU
Slide 11
CHLORHEXIDINE
Dr. Shahzadi Tayyaba
Hashmi
[email protected]
CHLORHEXIDINE
GLUCONATE
• Chlorhexidine gluconate is an effective
bactericidal agent and broad-spectrum
antimicrobial drug
• It has been extensively researched and is the
“gold standard” antimicrobial in oral hygiene
• Chlorhexidine is useful in many clinical
disciplines including periodontics, endodontics,
oral surgery and operative dentistry
INTRODUCTION
• Chlorhexidine is a broad-spectrum antimicrobial drug
• Acting as an antiseptic, it is an effective bactericidal
agent against all categories of microbes, including
bacteria, yeast and viruses
• Chlorhexidine was first used as a mouth rinse as an
adjunct to conventional non-surgical periodontal
therapy
• Chlorhexidine has proven efficacy as a broad-spectrum
antimicrobial for reducing supragingival plaque
PREVENTION OF DENTAL
CARIES
• There are a number of theories concerning the development and progression of
dental caries
• According to the specific Plaque hypothesis, only a limited number of bacteria
found in dental plaque can produce dental caries
• The most prominent among these bacteria are streptococcus mutans and
Lactobacilli
• Streptococcus mutans represent a group of closely related bacterial species that
are the primary species that initiate enamel caries
• Therefore patients with low mutans streptococci population levels in their oral
cavity generally have low caries activity and patients with high mutans
streptococci population levels generally high caries activity
• Lactobacilli are the primary causative species of dentinal caries
PREVENTION OF DENTAL
CARIES
• Chlorhexidine is a very potent bactericidal agent
for streptococcus mutans, the most significant
group of bacterium associated with dental caries
• Chlorhexidine molecules adhere to the surfaces
of streptococcus mutans and produce cell death
• For patients with a high risk of caries,
chlorhexidine rinses can be successfully used to
reduce the number of odontopathogenic bacteria
WHAT MAKES CHX UNIQUE
• Its long lasting bacteriostatic action, also termed as
‘substantivity’
• Its action lasts for about 12 hours in the oral cavity after a
single rinse
• The di-cationic CHX molecule, attaches to the pellicle by one
cation, to the bacteria attempting to colonize the tooth surface
with the other. This is called the ‘Pin-Cushion Effect’
• This prolongs the CHX action
USES
1. As an adjunct to oral hygiene
2. Post oral surgery including periodontal surgery or root
planning
3. In patients with inter maxillary fixation.
4. For oral hygiene & gingival health in physically & mentally
handicapped
5. Medically compromised individuals predisposed to oral
infections
6. High caries risk patient
7. Recurrent oral ulceration
8. Removable & fixed orthodontic wearers
9. Treatment of denture stomatitis and dry socket
10. As an immediate prophylactic rinse in the prevention of postextraction bacteremia
ADVERSE EFFECTS
a)
b)
c)
d)
e)
f)
Extrinsic staining
Alteration in taste perception
Oral mucosal erosion
Enhanced supragingival calculus formation
Parotid gland swelling
Over dosage ingestion of 1 or 2 ounces of CHX oral rinse by
a small child might result in gastric distress, including nausea
or signs of alcohol intoxication
DOSES AND ADMINISTRATION
• Recommended use is twice daily oral rinsing for 30 seconds
after tooth brushing
• Usual dosage is 15ml (1 tablespoon) of undiluted
chlorhexidine oral rinse
• Patient should be instructed not to rinse with water or brush
teeth or eat immediately after CHX oral rinse
• CHX should not be ingested and should be expectorated after
rinsing
AVAILABLE
FORMULATIONS
• Mouth rinse- aqueous/ alcohol solutions of 0.2% [Zordyl
,Clorasept]
• Gel [corsodyl dental gel]
• Sprays [Hibispray]
• Tooth pastes
• Varnishes
• Chewing gums
• Periodontal dressings
• Subgingival plaque control [Periochip]
THANK YOU