Nexus Drugs Private Limited Caring for health !! Nexus Drugs Private Limited Company Profile … Ready to Fill pre-formulation intermediates …
Download ReportTranscript Nexus Drugs Private Limited Caring for health !! Nexus Drugs Private Limited Company Profile … Ready to Fill pre-formulation intermediates …
Slide 1
Nexus Drugs Private Limited
Caring for health !!
Nexus Drugs Private Limited
Company Profile
… Ready to Fill
pre-formulation intermediates …
Slide 2
Welcome to
Nexus Drugs Private Limited
Your Search for Pharma Pellets of Enteric and Sustained quality ends here. We provide complete solutions for
delayed and controlled release pellets. Innovation of Pharma Pellets is ongoing process in our R&D.
Specialization
Customized solution for your formulation Development for specialized combination Product Dosages.
Our Vision
Meaningful relation with end-user of Pellets and understanding our customer needs. We continuously strive to help
our customers to sharpen their competitive edge by making medicines cost effective and affordable to enhance their
business value.
Our Strengths
We have Strong Customer Base and have CRAMS with major Pharma companies. Our clients are spread around the
globe.
Nexus Drugs Private Limited
Company Profile
… Ready to Fill
pre-formulation intermediates …
Slide 3
About Us
Innovation in the field of medicine and pharmaceuticals is an ongoing process. The objective is to provide cost
effective quality medicines to mitigate the sufferings of mankind.
Nexus Drugs is a fast growing organization established by a team of dedicated professionals with an experience
in the pharmaceutical industry with specific reference to the development and manufacture of various modified
release pellets.
The company’s forte is the customized development and manufacture of modified release pellets of various Active
Pharmaceutical Ingredients (APIs) including different combination blends in “Ready-To-Fill” in capsules.
A team of qualified and experienced technical personnel, well equipped manufacturing facility and Quality
Control, documentation system conforming to GMP requirements, have been instrumental in maintaining our
premium position in the Pharma Industry for the manufacture of pellets.
Nexus Drugs Private Limited
Company Profile
… Ready to Fill
pre-formulation intermediates …
Slide 4
Manufacturing
We have the best infrastructure to manufacture products of world-class quality, conforming to GMP norms.
Nexus Drugs Private Limited has adequate production capacities with specialized equipment's to meet the growing
market demand.
The salient features are:
Eco-friendly surroundings.
Unidirectional flow of materials.
Production on campaign basis.
Air handling units to meet class 100,000.
Corridors at highest positive pressure.
Purified water generation system to meet pharmacopeial requirements.
Oil and moisture free compressed air.
Capacity to manufacture 0.5 - 500 kg batch size.
Annual capacity of 600 MT.
Nexus Drugs Private Limited
Company Profile
… Ready to Fill
pre-formulation intermediates …
Slide 5
Quality
The Quality department at Nexus Drugs follows GLP recommendations and fulfills the requirement of Standards of the Regulatory
authorities.
The Lab is well equipped with latest qualified test Instruments, qualified and experienced Chemists, who believe in the mission for
quality not only in our products, but at each process stage.
The Quality Assurance department ensures that the products are manufactured and tested as per the requirements of GMP and ISO
9001:2008 Quality Management Systems.
Our quality policy covers:
Qualified Vendors
Qualified Equipment's
Qualified personnel
Well documented training Program
Validations
Approved sampling and testing procedures
Calibrations of monitoring and measuring equipment's
Change Control and Deviation Control
Safety, Health and Environment
Nexus Drugs Private Limited
Company Profile
… Ready to Fill
pre-formulation intermediates …
Slide 6
Product Development
Product development activities are headed by well experienced professionals having extensive knowledge on different
polymers behavior and their usage in the Drug delivery systems.
Nexus Drugs Private Limited has dedicated areas for product development and scale up studies before
commercialization.
At Nexus Drugs Private Limited Product development activity is an on-going process and statistically compare the
in-vitro drug release profiles against the originator products or as per market samples, where required we develop the
products as per customer specifications or in-house specifications based on literature.
Commercialization takes place after successful stability studies and validations as per ICH guidelines.
Nexus Drugs Private Limited
Company Profile
… Ready to Fill
pre-formulation intermediates …
Slide 7
Infrastructure
Nexus Drugs Private Limited owns a state-of-the-art infrastructural set-up. With a registered office in Hyderabad,
India, the manufacturing site is located in Pashamylaram, Patancheru, Medak District, A.P., India. This production
facility is amongst the largest manufacturers of omeprazole pellets in India. The production plant is constructed as
per the cGMP guidelines. Further, it also meets all the regulatory requirements of US FDA,WHO GMP, EDQM
etc.
The production unit is equipped with all types of manufacturing equipment's viz.:
Fluid bed coaters
Pulvarisers
Coating pans
Sifters
Tray dryers
Homogenizer
Double cone blender
Nexus Drugs Private Limited has established a countrywide sales and marketing network in India and abroad
through professionally trained and highly motivated professionals. Furthermore, the manufacturing unit is well
connected with efficient logistic network by air as well as sea to supply products to all places.
Nexus Drugs Private Limited
Company Profile
… Ready to Fill
pre-formulation intermediates …
Slide 8
Products
Sl.
No
01.
Omeprazole Pellets
7.50%, 8.50%, 10% & 20.0%
Anti Ulcerative
02.
Esomeprazole Mg Pellets
8.50%, 22.0% & 22.50 %
Anti Ulcerative
03.
Lansoprazole Pellets
8.50%
Anti Ulcerative
04.
Pantoprazole Sodium Pellets
15.0 % , & 22.50 %
Anti Ulcerative
05.
Itraconazole Pellets
22.0% & 35.0%
Anti Fungal
06.
Rabeprazole Sodium Pellets
8.50% & 11.20%
Anti Ulcerative
07.
Venlafaxine HCl SR Pellets
25.0% & 30.0%
Central Nervous System
08.
Diltiazem HCl SR Pellets
50.0 %
Anti Hypertensive
09.
Domperidone SR Pellets
10.0%, 30.0% & 40.0%
Anti Emetic
10.
Domperidone Pellets
20.0%
Anti Emetic
11.
Tamsulosin HCl CR Pellets
0.15% & 0.18%
Benign Prostatic Hyperplasia
12.
Metoprolol Succinate ER Pellets
44.0%
Cardiac
13.
Mebevarine HCl ER Pellets
48.0%
Anti-Spasmodic
14.
Ambroxol HCl SR Pellets
27.0%
Respiratory
15.
Itopride HCl SR Pellets
60.0%
Anti-Emetic
16.
Orlistat Pellets
50.0%
Anti-Obesity
17.
Duloxetine HCl Pellets
9.0% & 15.0%
Anti-Depressant
18.
Indomethacin SR Pellets
27.0%
Anti-Inflammatory,Analgesic
19.
Potassium Chloride SR Pellets
84.0%
Anti-nutrition
20.
Trihexy Phenidyl HCl SR Pellets
3.0%
Anti-Parkinson
21.
Blend Pellets of Rabeprazole Sodium EC Pellets + Domperidone SR Pellets
20mg + 30mg
Anti-Ulcerative + Anti Emetic
22.
Blended Pellets of Pantoprazole Pellets + Domperidone SR Pellets
40mg + 30mg
Anti-Ulcerative + Anti Emetic
23.
Propanolol HCl SR Pellets
54.0%
Anti-Hypertension
24.
Atorvastatin Pellets
7.82%, 10.0%, 15.63% & 20.0%
Anti-Hypertension
25.
Clopidogrel Bi Sulphate Pellets
50.0%
Cardiovascular,Coronary Artery
26.
Diclofenac Sodium SR Pellets
33.3%, 40.0% & 50.0%
Anti-Inflammatory, Analgesic
27.
Ketoprofen SR Pellets
70.0%
Anti-Inflammatory,Analgesic
Product Name
Nexus Drugs Private Limited
Company Profile
Strength
Therapeutic Use
… Ready to Fill
pre-formulation intermediates …
Slide 9
Forecasting for next 5 years
70
60
60
Turnover [Rs.Crores]
50
45
40
30
30
20
20
10
8.5
12
0
Financial Year
Nexus Drugs Private Limited
Company Profile
… Ready to Fill
pre-formulation intermediates …
Slide 10
Research & Development
Research & Development
Intense Research and Development efforts have been a great strength of Nexus Drugs Private Limited. The company
has developed ultra-modern R&D center integrated with the production facility. The center has capabilities to support
constant research. The various aspects of R&D are carried out by highly skilled scientists.
To carry out research and analytic experiments, the R&D center is equipped with different types of equipment's. Some
of them are:
Well equipped pilot scale equipment's
Fluid Bed Coater
Sifter
Pulverizer
Coating pan
Nexus Drugs Private Limited
Company Profile
… Ready to Fill
pre-formulation intermediates …
Slide 11
Research & Development
Expertise of the R& D center
Process Development for existing products
Modified drug release pellets with focus on 'Non-infringing Process Development'
Analytical Development
Development of New Products and processes
This Ensures
Smooth technological transfers
Effective and safe environmental technology
Cost reduction processes
Competence in providing DMF / Tech. pack along with the "Product Development Report"
Nexus Drugs Private Limited
Company Profile
… Ready to Fill
pre-formulation intermediates …
Slide 12
Value Proposition
Customer requirements
Contract research
& manufacturing
Value to
customer
Contract Research
A partner with process research abilities,
quality driven, environmental friendly and
low cost manufacturing capabilities
Tackle high cost and low productivity of
R&D
Leverage on intellectual capital and lower
cost of research in India
*Note: In the pyramid shown above, for a particular level-all the benefits of the levels below it are also applicable.
For example: At contract research level, all benefits mentioned against lease option are also applicable
Nexus Drugs Private Limited
Company Profile
… Ready to Fill
pre-formulation intermediates …
Slide 13
Committed to Deliver …
Customer
value
Infrastructure
Process
knowledge
Network
Human Capital
End-to-end
Track record
THANK YOU
Specific information on contract research facilities and capabilities can be furnished upon request
contact: [email protected]
Nexus Drugs Private Limited
Company Profile
… Ready to Fill
pre-formulation intermediates …
Nexus Drugs Private Limited
Caring for health !!
Nexus Drugs Private Limited
Company Profile
… Ready to Fill
pre-formulation intermediates …
Slide 2
Welcome to
Nexus Drugs Private Limited
Your Search for Pharma Pellets of Enteric and Sustained quality ends here. We provide complete solutions for
delayed and controlled release pellets. Innovation of Pharma Pellets is ongoing process in our R&D.
Specialization
Customized solution for your formulation Development for specialized combination Product Dosages.
Our Vision
Meaningful relation with end-user of Pellets and understanding our customer needs. We continuously strive to help
our customers to sharpen their competitive edge by making medicines cost effective and affordable to enhance their
business value.
Our Strengths
We have Strong Customer Base and have CRAMS with major Pharma companies. Our clients are spread around the
globe.
Nexus Drugs Private Limited
Company Profile
… Ready to Fill
pre-formulation intermediates …
Slide 3
About Us
Innovation in the field of medicine and pharmaceuticals is an ongoing process. The objective is to provide cost
effective quality medicines to mitigate the sufferings of mankind.
Nexus Drugs is a fast growing organization established by a team of dedicated professionals with an experience
in the pharmaceutical industry with specific reference to the development and manufacture of various modified
release pellets.
The company’s forte is the customized development and manufacture of modified release pellets of various Active
Pharmaceutical Ingredients (APIs) including different combination blends in “Ready-To-Fill” in capsules.
A team of qualified and experienced technical personnel, well equipped manufacturing facility and Quality
Control, documentation system conforming to GMP requirements, have been instrumental in maintaining our
premium position in the Pharma Industry for the manufacture of pellets.
Nexus Drugs Private Limited
Company Profile
… Ready to Fill
pre-formulation intermediates …
Slide 4
Manufacturing
We have the best infrastructure to manufacture products of world-class quality, conforming to GMP norms.
Nexus Drugs Private Limited has adequate production capacities with specialized equipment's to meet the growing
market demand.
The salient features are:
Eco-friendly surroundings.
Unidirectional flow of materials.
Production on campaign basis.
Air handling units to meet class 100,000.
Corridors at highest positive pressure.
Purified water generation system to meet pharmacopeial requirements.
Oil and moisture free compressed air.
Capacity to manufacture 0.5 - 500 kg batch size.
Annual capacity of 600 MT.
Nexus Drugs Private Limited
Company Profile
… Ready to Fill
pre-formulation intermediates …
Slide 5
Quality
The Quality department at Nexus Drugs follows GLP recommendations and fulfills the requirement of Standards of the Regulatory
authorities.
The Lab is well equipped with latest qualified test Instruments, qualified and experienced Chemists, who believe in the mission for
quality not only in our products, but at each process stage.
The Quality Assurance department ensures that the products are manufactured and tested as per the requirements of GMP and ISO
9001:2008 Quality Management Systems.
Our quality policy covers:
Qualified Vendors
Qualified Equipment's
Qualified personnel
Well documented training Program
Validations
Approved sampling and testing procedures
Calibrations of monitoring and measuring equipment's
Change Control and Deviation Control
Safety, Health and Environment
Nexus Drugs Private Limited
Company Profile
… Ready to Fill
pre-formulation intermediates …
Slide 6
Product Development
Product development activities are headed by well experienced professionals having extensive knowledge on different
polymers behavior and their usage in the Drug delivery systems.
Nexus Drugs Private Limited has dedicated areas for product development and scale up studies before
commercialization.
At Nexus Drugs Private Limited Product development activity is an on-going process and statistically compare the
in-vitro drug release profiles against the originator products or as per market samples, where required we develop the
products as per customer specifications or in-house specifications based on literature.
Commercialization takes place after successful stability studies and validations as per ICH guidelines.
Nexus Drugs Private Limited
Company Profile
… Ready to Fill
pre-formulation intermediates …
Slide 7
Infrastructure
Nexus Drugs Private Limited owns a state-of-the-art infrastructural set-up. With a registered office in Hyderabad,
India, the manufacturing site is located in Pashamylaram, Patancheru, Medak District, A.P., India. This production
facility is amongst the largest manufacturers of omeprazole pellets in India. The production plant is constructed as
per the cGMP guidelines. Further, it also meets all the regulatory requirements of US FDA,WHO GMP, EDQM
etc.
The production unit is equipped with all types of manufacturing equipment's viz.:
Fluid bed coaters
Pulvarisers
Coating pans
Sifters
Tray dryers
Homogenizer
Double cone blender
Nexus Drugs Private Limited has established a countrywide sales and marketing network in India and abroad
through professionally trained and highly motivated professionals. Furthermore, the manufacturing unit is well
connected with efficient logistic network by air as well as sea to supply products to all places.
Nexus Drugs Private Limited
Company Profile
… Ready to Fill
pre-formulation intermediates …
Slide 8
Products
Sl.
No
01.
Omeprazole Pellets
7.50%, 8.50%, 10% & 20.0%
Anti Ulcerative
02.
Esomeprazole Mg Pellets
8.50%, 22.0% & 22.50 %
Anti Ulcerative
03.
Lansoprazole Pellets
8.50%
Anti Ulcerative
04.
Pantoprazole Sodium Pellets
15.0 % , & 22.50 %
Anti Ulcerative
05.
Itraconazole Pellets
22.0% & 35.0%
Anti Fungal
06.
Rabeprazole Sodium Pellets
8.50% & 11.20%
Anti Ulcerative
07.
Venlafaxine HCl SR Pellets
25.0% & 30.0%
Central Nervous System
08.
Diltiazem HCl SR Pellets
50.0 %
Anti Hypertensive
09.
Domperidone SR Pellets
10.0%, 30.0% & 40.0%
Anti Emetic
10.
Domperidone Pellets
20.0%
Anti Emetic
11.
Tamsulosin HCl CR Pellets
0.15% & 0.18%
Benign Prostatic Hyperplasia
12.
Metoprolol Succinate ER Pellets
44.0%
Cardiac
13.
Mebevarine HCl ER Pellets
48.0%
Anti-Spasmodic
14.
Ambroxol HCl SR Pellets
27.0%
Respiratory
15.
Itopride HCl SR Pellets
60.0%
Anti-Emetic
16.
Orlistat Pellets
50.0%
Anti-Obesity
17.
Duloxetine HCl Pellets
9.0% & 15.0%
Anti-Depressant
18.
Indomethacin SR Pellets
27.0%
Anti-Inflammatory,Analgesic
19.
Potassium Chloride SR Pellets
84.0%
Anti-nutrition
20.
Trihexy Phenidyl HCl SR Pellets
3.0%
Anti-Parkinson
21.
Blend Pellets of Rabeprazole Sodium EC Pellets + Domperidone SR Pellets
20mg + 30mg
Anti-Ulcerative + Anti Emetic
22.
Blended Pellets of Pantoprazole Pellets + Domperidone SR Pellets
40mg + 30mg
Anti-Ulcerative + Anti Emetic
23.
Propanolol HCl SR Pellets
54.0%
Anti-Hypertension
24.
Atorvastatin Pellets
7.82%, 10.0%, 15.63% & 20.0%
Anti-Hypertension
25.
Clopidogrel Bi Sulphate Pellets
50.0%
Cardiovascular,Coronary Artery
26.
Diclofenac Sodium SR Pellets
33.3%, 40.0% & 50.0%
Anti-Inflammatory, Analgesic
27.
Ketoprofen SR Pellets
70.0%
Anti-Inflammatory,Analgesic
Product Name
Nexus Drugs Private Limited
Company Profile
Strength
Therapeutic Use
… Ready to Fill
pre-formulation intermediates …
Slide 9
Forecasting for next 5 years
70
60
60
Turnover [Rs.Crores]
50
45
40
30
30
20
20
10
8.5
12
0
Financial Year
Nexus Drugs Private Limited
Company Profile
… Ready to Fill
pre-formulation intermediates …
Slide 10
Research & Development
Research & Development
Intense Research and Development efforts have been a great strength of Nexus Drugs Private Limited. The company
has developed ultra-modern R&D center integrated with the production facility. The center has capabilities to support
constant research. The various aspects of R&D are carried out by highly skilled scientists.
To carry out research and analytic experiments, the R&D center is equipped with different types of equipment's. Some
of them are:
Well equipped pilot scale equipment's
Fluid Bed Coater
Sifter
Pulverizer
Coating pan
Nexus Drugs Private Limited
Company Profile
… Ready to Fill
pre-formulation intermediates …
Slide 11
Research & Development
Expertise of the R& D center
Process Development for existing products
Modified drug release pellets with focus on 'Non-infringing Process Development'
Analytical Development
Development of New Products and processes
This Ensures
Smooth technological transfers
Effective and safe environmental technology
Cost reduction processes
Competence in providing DMF / Tech. pack along with the "Product Development Report"
Nexus Drugs Private Limited
Company Profile
… Ready to Fill
pre-formulation intermediates …
Slide 12
Value Proposition
Customer requirements
Contract research
& manufacturing
Value to
customer
Contract Research
A partner with process research abilities,
quality driven, environmental friendly and
low cost manufacturing capabilities
Tackle high cost and low productivity of
R&D
Leverage on intellectual capital and lower
cost of research in India
*Note: In the pyramid shown above, for a particular level-all the benefits of the levels below it are also applicable.
For example: At contract research level, all benefits mentioned against lease option are also applicable
Nexus Drugs Private Limited
Company Profile
… Ready to Fill
pre-formulation intermediates …
Slide 13
Committed to Deliver …
Customer
value
Infrastructure
Process
knowledge
Network
Human Capital
End-to-end
Track record
THANK YOU
Specific information on contract research facilities and capabilities can be furnished upon request
contact: [email protected]
Nexus Drugs Private Limited
Company Profile
… Ready to Fill
pre-formulation intermediates …