Lifeblood Website Overview Message from Roche Medical expertise and artistic inspiration combine to create LIFEBLOOD: • a clinically accurate and visually stunning illustration of chronic kidney disease and renal anaemia • suitable.
Download ReportTranscript Lifeblood Website Overview Message from Roche Medical expertise and artistic inspiration combine to create LIFEBLOOD: • a clinically accurate and visually stunning illustration of chronic kidney disease and renal anaemia • suitable.
Slide 1
Lifeblood
Website
Overview
Message from Roche
Medical expertise and artistic
inspiration combine to create
LIFEBLOOD:
• a clinically accurate and
visually stunning
illustration of chronic
kidney disease and renal
anaemia
• suitable for both medical
professionals and their
patients
How Lifeblood
was developed
• Digital slices of the body from
medical imaging devices are
built into 3D models of
tissues and organs.
• Enhanced and highlighted,
these detailed and
informative images explain
the complex processes of the
human body.
CKD & Anaemia
Anaemia is typically present with a
diagnosis of CKD –as the
diseased kidneys produce less of
the vital hormone erythropoietin
that’s needed to stimulate
production of red blood cells in the
bone marrow.
Loss of kidney
function
Reduced kidney function leads to:
• imbalance of volume and solutes
• anaemia
• bone disease
• metabolic acidosis
Kidney failure leads to uraemia –
the accumulation in the blood of
toxins usually excreted by the
kidney.
Common
causes of CKD
• hypertension
• obstructions in the urinary
tract (e.g. kidney stones)
• polycystic kidney disease
• glomerulonephritis
• recent urinary infections
• diabetes
• developmental
malformations
• autoimmune diseases
Marvel at our
Anatomy
• The kidneys maintain the
body’s balance, regulating
levels of water and salts.
• The kidneys are key to
vitality. When oxygen
levels are low they produce
erythropoietin, stimulating
the bone marrow to
produce oxygen-carrying
red blood cells.
Blood
transmission
• Blood is forced through an
intricate network of
glomerular capillary tufts
in the kidney.
• Water and waste products
flow out across the
glomerular filtration barrier
into the bowman’s space, to
be excreted as urine.
Causes & impact
of CKD
• The main causes of CKD in
developed countries are linked
to poor lifestyle choices.
• Hypertension and diabetes
silently damage the kidney
blood vessels.
• Heightened blood pressure in
the damaged capillaries can
lead to further damage and
kidney failure.
Diagnosis
• Patients with CKD
warning signs like
hypertension and
diabetes require close
monitoring.
• The estimated
glomerular filtration rate
(eGFR) can be
calculated from a blood
test and provides an
assessment of the
overall kidney function.
Treatment
• Haemodialysis and
peritoneal dialysis are
methods to help
remove toxins from the
blood when the kidneys
stop functioning.
• Another option for
patients may be kidney
transplantation.
Slide 2
Lifeblood
Website
Overview
Message from Roche
Medical expertise and artistic
inspiration combine to create
LIFEBLOOD:
• a clinically accurate and
visually stunning
illustration of chronic
kidney disease and renal
anaemia
• suitable for both medical
professionals and their
patients
How Lifeblood
was developed
• Digital slices of the body from
medical imaging devices are
built into 3D models of
tissues and organs.
• Enhanced and highlighted,
these detailed and
informative images explain
the complex processes of the
human body.
CKD & Anaemia
Anaemia is typically present with a
diagnosis of CKD –as the
diseased kidneys produce less of
the vital hormone erythropoietin
that’s needed to stimulate
production of red blood cells in the
bone marrow.
Loss of kidney
function
Reduced kidney function leads to:
• imbalance of volume and solutes
• anaemia
• bone disease
• metabolic acidosis
Kidney failure leads to uraemia –
the accumulation in the blood of
toxins usually excreted by the
kidney.
Common
causes of CKD
• hypertension
• obstructions in the urinary
tract (e.g. kidney stones)
• polycystic kidney disease
• glomerulonephritis
• recent urinary infections
• diabetes
• developmental
malformations
• autoimmune diseases
Marvel at our
Anatomy
• The kidneys maintain the
body’s balance, regulating
levels of water and salts.
• The kidneys are key to
vitality. When oxygen
levels are low they produce
erythropoietin, stimulating
the bone marrow to
produce oxygen-carrying
red blood cells.
Blood
transmission
• Blood is forced through an
intricate network of
glomerular capillary tufts
in the kidney.
• Water and waste products
flow out across the
glomerular filtration barrier
into the bowman’s space, to
be excreted as urine.
Causes & impact
of CKD
• The main causes of CKD in
developed countries are linked
to poor lifestyle choices.
• Hypertension and diabetes
silently damage the kidney
blood vessels.
• Heightened blood pressure in
the damaged capillaries can
lead to further damage and
kidney failure.
Diagnosis
• Patients with CKD
warning signs like
hypertension and
diabetes require close
monitoring.
• The estimated
glomerular filtration rate
(eGFR) can be
calculated from a blood
test and provides an
assessment of the
overall kidney function.
Treatment
• Haemodialysis and
peritoneal dialysis are
methods to help
remove toxins from the
blood when the kidneys
stop functioning.
• Another option for
patients may be kidney
transplantation.
Slide 3
Lifeblood
Website
Overview
Message from Roche
Medical expertise and artistic
inspiration combine to create
LIFEBLOOD:
• a clinically accurate and
visually stunning
illustration of chronic
kidney disease and renal
anaemia
• suitable for both medical
professionals and their
patients
How Lifeblood
was developed
• Digital slices of the body from
medical imaging devices are
built into 3D models of
tissues and organs.
• Enhanced and highlighted,
these detailed and
informative images explain
the complex processes of the
human body.
CKD & Anaemia
Anaemia is typically present with a
diagnosis of CKD –as the
diseased kidneys produce less of
the vital hormone erythropoietin
that’s needed to stimulate
production of red blood cells in the
bone marrow.
Loss of kidney
function
Reduced kidney function leads to:
• imbalance of volume and solutes
• anaemia
• bone disease
• metabolic acidosis
Kidney failure leads to uraemia –
the accumulation in the blood of
toxins usually excreted by the
kidney.
Common
causes of CKD
• hypertension
• obstructions in the urinary
tract (e.g. kidney stones)
• polycystic kidney disease
• glomerulonephritis
• recent urinary infections
• diabetes
• developmental
malformations
• autoimmune diseases
Marvel at our
Anatomy
• The kidneys maintain the
body’s balance, regulating
levels of water and salts.
• The kidneys are key to
vitality. When oxygen
levels are low they produce
erythropoietin, stimulating
the bone marrow to
produce oxygen-carrying
red blood cells.
Blood
transmission
• Blood is forced through an
intricate network of
glomerular capillary tufts
in the kidney.
• Water and waste products
flow out across the
glomerular filtration barrier
into the bowman’s space, to
be excreted as urine.
Causes & impact
of CKD
• The main causes of CKD in
developed countries are linked
to poor lifestyle choices.
• Hypertension and diabetes
silently damage the kidney
blood vessels.
• Heightened blood pressure in
the damaged capillaries can
lead to further damage and
kidney failure.
Diagnosis
• Patients with CKD
warning signs like
hypertension and
diabetes require close
monitoring.
• The estimated
glomerular filtration rate
(eGFR) can be
calculated from a blood
test and provides an
assessment of the
overall kidney function.
Treatment
• Haemodialysis and
peritoneal dialysis are
methods to help
remove toxins from the
blood when the kidneys
stop functioning.
• Another option for
patients may be kidney
transplantation.
Slide 4
Lifeblood
Website
Overview
Message from Roche
Medical expertise and artistic
inspiration combine to create
LIFEBLOOD:
• a clinically accurate and
visually stunning
illustration of chronic
kidney disease and renal
anaemia
• suitable for both medical
professionals and their
patients
How Lifeblood
was developed
• Digital slices of the body from
medical imaging devices are
built into 3D models of
tissues and organs.
• Enhanced and highlighted,
these detailed and
informative images explain
the complex processes of the
human body.
CKD & Anaemia
Anaemia is typically present with a
diagnosis of CKD –as the
diseased kidneys produce less of
the vital hormone erythropoietin
that’s needed to stimulate
production of red blood cells in the
bone marrow.
Loss of kidney
function
Reduced kidney function leads to:
• imbalance of volume and solutes
• anaemia
• bone disease
• metabolic acidosis
Kidney failure leads to uraemia –
the accumulation in the blood of
toxins usually excreted by the
kidney.
Common
causes of CKD
• hypertension
• obstructions in the urinary
tract (e.g. kidney stones)
• polycystic kidney disease
• glomerulonephritis
• recent urinary infections
• diabetes
• developmental
malformations
• autoimmune diseases
Marvel at our
Anatomy
• The kidneys maintain the
body’s balance, regulating
levels of water and salts.
• The kidneys are key to
vitality. When oxygen
levels are low they produce
erythropoietin, stimulating
the bone marrow to
produce oxygen-carrying
red blood cells.
Blood
transmission
• Blood is forced through an
intricate network of
glomerular capillary tufts
in the kidney.
• Water and waste products
flow out across the
glomerular filtration barrier
into the bowman’s space, to
be excreted as urine.
Causes & impact
of CKD
• The main causes of CKD in
developed countries are linked
to poor lifestyle choices.
• Hypertension and diabetes
silently damage the kidney
blood vessels.
• Heightened blood pressure in
the damaged capillaries can
lead to further damage and
kidney failure.
Diagnosis
• Patients with CKD
warning signs like
hypertension and
diabetes require close
monitoring.
• The estimated
glomerular filtration rate
(eGFR) can be
calculated from a blood
test and provides an
assessment of the
overall kidney function.
Treatment
• Haemodialysis and
peritoneal dialysis are
methods to help
remove toxins from the
blood when the kidneys
stop functioning.
• Another option for
patients may be kidney
transplantation.
Slide 5
Lifeblood
Website
Overview
Message from Roche
Medical expertise and artistic
inspiration combine to create
LIFEBLOOD:
• a clinically accurate and
visually stunning
illustration of chronic
kidney disease and renal
anaemia
• suitable for both medical
professionals and their
patients
How Lifeblood
was developed
• Digital slices of the body from
medical imaging devices are
built into 3D models of
tissues and organs.
• Enhanced and highlighted,
these detailed and
informative images explain
the complex processes of the
human body.
CKD & Anaemia
Anaemia is typically present with a
diagnosis of CKD –as the
diseased kidneys produce less of
the vital hormone erythropoietin
that’s needed to stimulate
production of red blood cells in the
bone marrow.
Loss of kidney
function
Reduced kidney function leads to:
• imbalance of volume and solutes
• anaemia
• bone disease
• metabolic acidosis
Kidney failure leads to uraemia –
the accumulation in the blood of
toxins usually excreted by the
kidney.
Common
causes of CKD
• hypertension
• obstructions in the urinary
tract (e.g. kidney stones)
• polycystic kidney disease
• glomerulonephritis
• recent urinary infections
• diabetes
• developmental
malformations
• autoimmune diseases
Marvel at our
Anatomy
• The kidneys maintain the
body’s balance, regulating
levels of water and salts.
• The kidneys are key to
vitality. When oxygen
levels are low they produce
erythropoietin, stimulating
the bone marrow to
produce oxygen-carrying
red blood cells.
Blood
transmission
• Blood is forced through an
intricate network of
glomerular capillary tufts
in the kidney.
• Water and waste products
flow out across the
glomerular filtration barrier
into the bowman’s space, to
be excreted as urine.
Causes & impact
of CKD
• The main causes of CKD in
developed countries are linked
to poor lifestyle choices.
• Hypertension and diabetes
silently damage the kidney
blood vessels.
• Heightened blood pressure in
the damaged capillaries can
lead to further damage and
kidney failure.
Diagnosis
• Patients with CKD
warning signs like
hypertension and
diabetes require close
monitoring.
• The estimated
glomerular filtration rate
(eGFR) can be
calculated from a blood
test and provides an
assessment of the
overall kidney function.
Treatment
• Haemodialysis and
peritoneal dialysis are
methods to help
remove toxins from the
blood when the kidneys
stop functioning.
• Another option for
patients may be kidney
transplantation.
Slide 6
Lifeblood
Website
Overview
Message from Roche
Medical expertise and artistic
inspiration combine to create
LIFEBLOOD:
• a clinically accurate and
visually stunning
illustration of chronic
kidney disease and renal
anaemia
• suitable for both medical
professionals and their
patients
How Lifeblood
was developed
• Digital slices of the body from
medical imaging devices are
built into 3D models of
tissues and organs.
• Enhanced and highlighted,
these detailed and
informative images explain
the complex processes of the
human body.
CKD & Anaemia
Anaemia is typically present with a
diagnosis of CKD –as the
diseased kidneys produce less of
the vital hormone erythropoietin
that’s needed to stimulate
production of red blood cells in the
bone marrow.
Loss of kidney
function
Reduced kidney function leads to:
• imbalance of volume and solutes
• anaemia
• bone disease
• metabolic acidosis
Kidney failure leads to uraemia –
the accumulation in the blood of
toxins usually excreted by the
kidney.
Common
causes of CKD
• hypertension
• obstructions in the urinary
tract (e.g. kidney stones)
• polycystic kidney disease
• glomerulonephritis
• recent urinary infections
• diabetes
• developmental
malformations
• autoimmune diseases
Marvel at our
Anatomy
• The kidneys maintain the
body’s balance, regulating
levels of water and salts.
• The kidneys are key to
vitality. When oxygen
levels are low they produce
erythropoietin, stimulating
the bone marrow to
produce oxygen-carrying
red blood cells.
Blood
transmission
• Blood is forced through an
intricate network of
glomerular capillary tufts
in the kidney.
• Water and waste products
flow out across the
glomerular filtration barrier
into the bowman’s space, to
be excreted as urine.
Causes & impact
of CKD
• The main causes of CKD in
developed countries are linked
to poor lifestyle choices.
• Hypertension and diabetes
silently damage the kidney
blood vessels.
• Heightened blood pressure in
the damaged capillaries can
lead to further damage and
kidney failure.
Diagnosis
• Patients with CKD
warning signs like
hypertension and
diabetes require close
monitoring.
• The estimated
glomerular filtration rate
(eGFR) can be
calculated from a blood
test and provides an
assessment of the
overall kidney function.
Treatment
• Haemodialysis and
peritoneal dialysis are
methods to help
remove toxins from the
blood when the kidneys
stop functioning.
• Another option for
patients may be kidney
transplantation.
Slide 7
Lifeblood
Website
Overview
Message from Roche
Medical expertise and artistic
inspiration combine to create
LIFEBLOOD:
• a clinically accurate and
visually stunning
illustration of chronic
kidney disease and renal
anaemia
• suitable for both medical
professionals and their
patients
How Lifeblood
was developed
• Digital slices of the body from
medical imaging devices are
built into 3D models of
tissues and organs.
• Enhanced and highlighted,
these detailed and
informative images explain
the complex processes of the
human body.
CKD & Anaemia
Anaemia is typically present with a
diagnosis of CKD –as the
diseased kidneys produce less of
the vital hormone erythropoietin
that’s needed to stimulate
production of red blood cells in the
bone marrow.
Loss of kidney
function
Reduced kidney function leads to:
• imbalance of volume and solutes
• anaemia
• bone disease
• metabolic acidosis
Kidney failure leads to uraemia –
the accumulation in the blood of
toxins usually excreted by the
kidney.
Common
causes of CKD
• hypertension
• obstructions in the urinary
tract (e.g. kidney stones)
• polycystic kidney disease
• glomerulonephritis
• recent urinary infections
• diabetes
• developmental
malformations
• autoimmune diseases
Marvel at our
Anatomy
• The kidneys maintain the
body’s balance, regulating
levels of water and salts.
• The kidneys are key to
vitality. When oxygen
levels are low they produce
erythropoietin, stimulating
the bone marrow to
produce oxygen-carrying
red blood cells.
Blood
transmission
• Blood is forced through an
intricate network of
glomerular capillary tufts
in the kidney.
• Water and waste products
flow out across the
glomerular filtration barrier
into the bowman’s space, to
be excreted as urine.
Causes & impact
of CKD
• The main causes of CKD in
developed countries are linked
to poor lifestyle choices.
• Hypertension and diabetes
silently damage the kidney
blood vessels.
• Heightened blood pressure in
the damaged capillaries can
lead to further damage and
kidney failure.
Diagnosis
• Patients with CKD
warning signs like
hypertension and
diabetes require close
monitoring.
• The estimated
glomerular filtration rate
(eGFR) can be
calculated from a blood
test and provides an
assessment of the
overall kidney function.
Treatment
• Haemodialysis and
peritoneal dialysis are
methods to help
remove toxins from the
blood when the kidneys
stop functioning.
• Another option for
patients may be kidney
transplantation.
Slide 8
Lifeblood
Website
Overview
Message from Roche
Medical expertise and artistic
inspiration combine to create
LIFEBLOOD:
• a clinically accurate and
visually stunning
illustration of chronic
kidney disease and renal
anaemia
• suitable for both medical
professionals and their
patients
How Lifeblood
was developed
• Digital slices of the body from
medical imaging devices are
built into 3D models of
tissues and organs.
• Enhanced and highlighted,
these detailed and
informative images explain
the complex processes of the
human body.
CKD & Anaemia
Anaemia is typically present with a
diagnosis of CKD –as the
diseased kidneys produce less of
the vital hormone erythropoietin
that’s needed to stimulate
production of red blood cells in the
bone marrow.
Loss of kidney
function
Reduced kidney function leads to:
• imbalance of volume and solutes
• anaemia
• bone disease
• metabolic acidosis
Kidney failure leads to uraemia –
the accumulation in the blood of
toxins usually excreted by the
kidney.
Common
causes of CKD
• hypertension
• obstructions in the urinary
tract (e.g. kidney stones)
• polycystic kidney disease
• glomerulonephritis
• recent urinary infections
• diabetes
• developmental
malformations
• autoimmune diseases
Marvel at our
Anatomy
• The kidneys maintain the
body’s balance, regulating
levels of water and salts.
• The kidneys are key to
vitality. When oxygen
levels are low they produce
erythropoietin, stimulating
the bone marrow to
produce oxygen-carrying
red blood cells.
Blood
transmission
• Blood is forced through an
intricate network of
glomerular capillary tufts
in the kidney.
• Water and waste products
flow out across the
glomerular filtration barrier
into the bowman’s space, to
be excreted as urine.
Causes & impact
of CKD
• The main causes of CKD in
developed countries are linked
to poor lifestyle choices.
• Hypertension and diabetes
silently damage the kidney
blood vessels.
• Heightened blood pressure in
the damaged capillaries can
lead to further damage and
kidney failure.
Diagnosis
• Patients with CKD
warning signs like
hypertension and
diabetes require close
monitoring.
• The estimated
glomerular filtration rate
(eGFR) can be
calculated from a blood
test and provides an
assessment of the
overall kidney function.
Treatment
• Haemodialysis and
peritoneal dialysis are
methods to help
remove toxins from the
blood when the kidneys
stop functioning.
• Another option for
patients may be kidney
transplantation.
Slide 9
Lifeblood
Website
Overview
Message from Roche
Medical expertise and artistic
inspiration combine to create
LIFEBLOOD:
• a clinically accurate and
visually stunning
illustration of chronic
kidney disease and renal
anaemia
• suitable for both medical
professionals and their
patients
How Lifeblood
was developed
• Digital slices of the body from
medical imaging devices are
built into 3D models of
tissues and organs.
• Enhanced and highlighted,
these detailed and
informative images explain
the complex processes of the
human body.
CKD & Anaemia
Anaemia is typically present with a
diagnosis of CKD –as the
diseased kidneys produce less of
the vital hormone erythropoietin
that’s needed to stimulate
production of red blood cells in the
bone marrow.
Loss of kidney
function
Reduced kidney function leads to:
• imbalance of volume and solutes
• anaemia
• bone disease
• metabolic acidosis
Kidney failure leads to uraemia –
the accumulation in the blood of
toxins usually excreted by the
kidney.
Common
causes of CKD
• hypertension
• obstructions in the urinary
tract (e.g. kidney stones)
• polycystic kidney disease
• glomerulonephritis
• recent urinary infections
• diabetes
• developmental
malformations
• autoimmune diseases
Marvel at our
Anatomy
• The kidneys maintain the
body’s balance, regulating
levels of water and salts.
• The kidneys are key to
vitality. When oxygen
levels are low they produce
erythropoietin, stimulating
the bone marrow to
produce oxygen-carrying
red blood cells.
Blood
transmission
• Blood is forced through an
intricate network of
glomerular capillary tufts
in the kidney.
• Water and waste products
flow out across the
glomerular filtration barrier
into the bowman’s space, to
be excreted as urine.
Causes & impact
of CKD
• The main causes of CKD in
developed countries are linked
to poor lifestyle choices.
• Hypertension and diabetes
silently damage the kidney
blood vessels.
• Heightened blood pressure in
the damaged capillaries can
lead to further damage and
kidney failure.
Diagnosis
• Patients with CKD
warning signs like
hypertension and
diabetes require close
monitoring.
• The estimated
glomerular filtration rate
(eGFR) can be
calculated from a blood
test and provides an
assessment of the
overall kidney function.
Treatment
• Haemodialysis and
peritoneal dialysis are
methods to help
remove toxins from the
blood when the kidneys
stop functioning.
• Another option for
patients may be kidney
transplantation.
Slide 10
Lifeblood
Website
Overview
Message from Roche
Medical expertise and artistic
inspiration combine to create
LIFEBLOOD:
• a clinically accurate and
visually stunning
illustration of chronic
kidney disease and renal
anaemia
• suitable for both medical
professionals and their
patients
How Lifeblood
was developed
• Digital slices of the body from
medical imaging devices are
built into 3D models of
tissues and organs.
• Enhanced and highlighted,
these detailed and
informative images explain
the complex processes of the
human body.
CKD & Anaemia
Anaemia is typically present with a
diagnosis of CKD –as the
diseased kidneys produce less of
the vital hormone erythropoietin
that’s needed to stimulate
production of red blood cells in the
bone marrow.
Loss of kidney
function
Reduced kidney function leads to:
• imbalance of volume and solutes
• anaemia
• bone disease
• metabolic acidosis
Kidney failure leads to uraemia –
the accumulation in the blood of
toxins usually excreted by the
kidney.
Common
causes of CKD
• hypertension
• obstructions in the urinary
tract (e.g. kidney stones)
• polycystic kidney disease
• glomerulonephritis
• recent urinary infections
• diabetes
• developmental
malformations
• autoimmune diseases
Marvel at our
Anatomy
• The kidneys maintain the
body’s balance, regulating
levels of water and salts.
• The kidneys are key to
vitality. When oxygen
levels are low they produce
erythropoietin, stimulating
the bone marrow to
produce oxygen-carrying
red blood cells.
Blood
transmission
• Blood is forced through an
intricate network of
glomerular capillary tufts
in the kidney.
• Water and waste products
flow out across the
glomerular filtration barrier
into the bowman’s space, to
be excreted as urine.
Causes & impact
of CKD
• The main causes of CKD in
developed countries are linked
to poor lifestyle choices.
• Hypertension and diabetes
silently damage the kidney
blood vessels.
• Heightened blood pressure in
the damaged capillaries can
lead to further damage and
kidney failure.
Diagnosis
• Patients with CKD
warning signs like
hypertension and
diabetes require close
monitoring.
• The estimated
glomerular filtration rate
(eGFR) can be
calculated from a blood
test and provides an
assessment of the
overall kidney function.
Treatment
• Haemodialysis and
peritoneal dialysis are
methods to help
remove toxins from the
blood when the kidneys
stop functioning.
• Another option for
patients may be kidney
transplantation.
Slide 11
Lifeblood
Website
Overview
Message from Roche
Medical expertise and artistic
inspiration combine to create
LIFEBLOOD:
• a clinically accurate and
visually stunning
illustration of chronic
kidney disease and renal
anaemia
• suitable for both medical
professionals and their
patients
How Lifeblood
was developed
• Digital slices of the body from
medical imaging devices are
built into 3D models of
tissues and organs.
• Enhanced and highlighted,
these detailed and
informative images explain
the complex processes of the
human body.
CKD & Anaemia
Anaemia is typically present with a
diagnosis of CKD –as the
diseased kidneys produce less of
the vital hormone erythropoietin
that’s needed to stimulate
production of red blood cells in the
bone marrow.
Loss of kidney
function
Reduced kidney function leads to:
• imbalance of volume and solutes
• anaemia
• bone disease
• metabolic acidosis
Kidney failure leads to uraemia –
the accumulation in the blood of
toxins usually excreted by the
kidney.
Common
causes of CKD
• hypertension
• obstructions in the urinary
tract (e.g. kidney stones)
• polycystic kidney disease
• glomerulonephritis
• recent urinary infections
• diabetes
• developmental
malformations
• autoimmune diseases
Marvel at our
Anatomy
• The kidneys maintain the
body’s balance, regulating
levels of water and salts.
• The kidneys are key to
vitality. When oxygen
levels are low they produce
erythropoietin, stimulating
the bone marrow to
produce oxygen-carrying
red blood cells.
Blood
transmission
• Blood is forced through an
intricate network of
glomerular capillary tufts
in the kidney.
• Water and waste products
flow out across the
glomerular filtration barrier
into the bowman’s space, to
be excreted as urine.
Causes & impact
of CKD
• The main causes of CKD in
developed countries are linked
to poor lifestyle choices.
• Hypertension and diabetes
silently damage the kidney
blood vessels.
• Heightened blood pressure in
the damaged capillaries can
lead to further damage and
kidney failure.
Diagnosis
• Patients with CKD
warning signs like
hypertension and
diabetes require close
monitoring.
• The estimated
glomerular filtration rate
(eGFR) can be
calculated from a blood
test and provides an
assessment of the
overall kidney function.
Treatment
• Haemodialysis and
peritoneal dialysis are
methods to help
remove toxins from the
blood when the kidneys
stop functioning.
• Another option for
patients may be kidney
transplantation.
Lifeblood
Website
Overview
Message from Roche
Medical expertise and artistic
inspiration combine to create
LIFEBLOOD:
• a clinically accurate and
visually stunning
illustration of chronic
kidney disease and renal
anaemia
• suitable for both medical
professionals and their
patients
How Lifeblood
was developed
• Digital slices of the body from
medical imaging devices are
built into 3D models of
tissues and organs.
• Enhanced and highlighted,
these detailed and
informative images explain
the complex processes of the
human body.
CKD & Anaemia
Anaemia is typically present with a
diagnosis of CKD –as the
diseased kidneys produce less of
the vital hormone erythropoietin
that’s needed to stimulate
production of red blood cells in the
bone marrow.
Loss of kidney
function
Reduced kidney function leads to:
• imbalance of volume and solutes
• anaemia
• bone disease
• metabolic acidosis
Kidney failure leads to uraemia –
the accumulation in the blood of
toxins usually excreted by the
kidney.
Common
causes of CKD
• hypertension
• obstructions in the urinary
tract (e.g. kidney stones)
• polycystic kidney disease
• glomerulonephritis
• recent urinary infections
• diabetes
• developmental
malformations
• autoimmune diseases
Marvel at our
Anatomy
• The kidneys maintain the
body’s balance, regulating
levels of water and salts.
• The kidneys are key to
vitality. When oxygen
levels are low they produce
erythropoietin, stimulating
the bone marrow to
produce oxygen-carrying
red blood cells.
Blood
transmission
• Blood is forced through an
intricate network of
glomerular capillary tufts
in the kidney.
• Water and waste products
flow out across the
glomerular filtration barrier
into the bowman’s space, to
be excreted as urine.
Causes & impact
of CKD
• The main causes of CKD in
developed countries are linked
to poor lifestyle choices.
• Hypertension and diabetes
silently damage the kidney
blood vessels.
• Heightened blood pressure in
the damaged capillaries can
lead to further damage and
kidney failure.
Diagnosis
• Patients with CKD
warning signs like
hypertension and
diabetes require close
monitoring.
• The estimated
glomerular filtration rate
(eGFR) can be
calculated from a blood
test and provides an
assessment of the
overall kidney function.
Treatment
• Haemodialysis and
peritoneal dialysis are
methods to help
remove toxins from the
blood when the kidneys
stop functioning.
• Another option for
patients may be kidney
transplantation.
Slide 2
Lifeblood
Website
Overview
Message from Roche
Medical expertise and artistic
inspiration combine to create
LIFEBLOOD:
• a clinically accurate and
visually stunning
illustration of chronic
kidney disease and renal
anaemia
• suitable for both medical
professionals and their
patients
How Lifeblood
was developed
• Digital slices of the body from
medical imaging devices are
built into 3D models of
tissues and organs.
• Enhanced and highlighted,
these detailed and
informative images explain
the complex processes of the
human body.
CKD & Anaemia
Anaemia is typically present with a
diagnosis of CKD –as the
diseased kidneys produce less of
the vital hormone erythropoietin
that’s needed to stimulate
production of red blood cells in the
bone marrow.
Loss of kidney
function
Reduced kidney function leads to:
• imbalance of volume and solutes
• anaemia
• bone disease
• metabolic acidosis
Kidney failure leads to uraemia –
the accumulation in the blood of
toxins usually excreted by the
kidney.
Common
causes of CKD
• hypertension
• obstructions in the urinary
tract (e.g. kidney stones)
• polycystic kidney disease
• glomerulonephritis
• recent urinary infections
• diabetes
• developmental
malformations
• autoimmune diseases
Marvel at our
Anatomy
• The kidneys maintain the
body’s balance, regulating
levels of water and salts.
• The kidneys are key to
vitality. When oxygen
levels are low they produce
erythropoietin, stimulating
the bone marrow to
produce oxygen-carrying
red blood cells.
Blood
transmission
• Blood is forced through an
intricate network of
glomerular capillary tufts
in the kidney.
• Water and waste products
flow out across the
glomerular filtration barrier
into the bowman’s space, to
be excreted as urine.
Causes & impact
of CKD
• The main causes of CKD in
developed countries are linked
to poor lifestyle choices.
• Hypertension and diabetes
silently damage the kidney
blood vessels.
• Heightened blood pressure in
the damaged capillaries can
lead to further damage and
kidney failure.
Diagnosis
• Patients with CKD
warning signs like
hypertension and
diabetes require close
monitoring.
• The estimated
glomerular filtration rate
(eGFR) can be
calculated from a blood
test and provides an
assessment of the
overall kidney function.
Treatment
• Haemodialysis and
peritoneal dialysis are
methods to help
remove toxins from the
blood when the kidneys
stop functioning.
• Another option for
patients may be kidney
transplantation.
Slide 3
Lifeblood
Website
Overview
Message from Roche
Medical expertise and artistic
inspiration combine to create
LIFEBLOOD:
• a clinically accurate and
visually stunning
illustration of chronic
kidney disease and renal
anaemia
• suitable for both medical
professionals and their
patients
How Lifeblood
was developed
• Digital slices of the body from
medical imaging devices are
built into 3D models of
tissues and organs.
• Enhanced and highlighted,
these detailed and
informative images explain
the complex processes of the
human body.
CKD & Anaemia
Anaemia is typically present with a
diagnosis of CKD –as the
diseased kidneys produce less of
the vital hormone erythropoietin
that’s needed to stimulate
production of red blood cells in the
bone marrow.
Loss of kidney
function
Reduced kidney function leads to:
• imbalance of volume and solutes
• anaemia
• bone disease
• metabolic acidosis
Kidney failure leads to uraemia –
the accumulation in the blood of
toxins usually excreted by the
kidney.
Common
causes of CKD
• hypertension
• obstructions in the urinary
tract (e.g. kidney stones)
• polycystic kidney disease
• glomerulonephritis
• recent urinary infections
• diabetes
• developmental
malformations
• autoimmune diseases
Marvel at our
Anatomy
• The kidneys maintain the
body’s balance, regulating
levels of water and salts.
• The kidneys are key to
vitality. When oxygen
levels are low they produce
erythropoietin, stimulating
the bone marrow to
produce oxygen-carrying
red blood cells.
Blood
transmission
• Blood is forced through an
intricate network of
glomerular capillary tufts
in the kidney.
• Water and waste products
flow out across the
glomerular filtration barrier
into the bowman’s space, to
be excreted as urine.
Causes & impact
of CKD
• The main causes of CKD in
developed countries are linked
to poor lifestyle choices.
• Hypertension and diabetes
silently damage the kidney
blood vessels.
• Heightened blood pressure in
the damaged capillaries can
lead to further damage and
kidney failure.
Diagnosis
• Patients with CKD
warning signs like
hypertension and
diabetes require close
monitoring.
• The estimated
glomerular filtration rate
(eGFR) can be
calculated from a blood
test and provides an
assessment of the
overall kidney function.
Treatment
• Haemodialysis and
peritoneal dialysis are
methods to help
remove toxins from the
blood when the kidneys
stop functioning.
• Another option for
patients may be kidney
transplantation.
Slide 4
Lifeblood
Website
Overview
Message from Roche
Medical expertise and artistic
inspiration combine to create
LIFEBLOOD:
• a clinically accurate and
visually stunning
illustration of chronic
kidney disease and renal
anaemia
• suitable for both medical
professionals and their
patients
How Lifeblood
was developed
• Digital slices of the body from
medical imaging devices are
built into 3D models of
tissues and organs.
• Enhanced and highlighted,
these detailed and
informative images explain
the complex processes of the
human body.
CKD & Anaemia
Anaemia is typically present with a
diagnosis of CKD –as the
diseased kidneys produce less of
the vital hormone erythropoietin
that’s needed to stimulate
production of red blood cells in the
bone marrow.
Loss of kidney
function
Reduced kidney function leads to:
• imbalance of volume and solutes
• anaemia
• bone disease
• metabolic acidosis
Kidney failure leads to uraemia –
the accumulation in the blood of
toxins usually excreted by the
kidney.
Common
causes of CKD
• hypertension
• obstructions in the urinary
tract (e.g. kidney stones)
• polycystic kidney disease
• glomerulonephritis
• recent urinary infections
• diabetes
• developmental
malformations
• autoimmune diseases
Marvel at our
Anatomy
• The kidneys maintain the
body’s balance, regulating
levels of water and salts.
• The kidneys are key to
vitality. When oxygen
levels are low they produce
erythropoietin, stimulating
the bone marrow to
produce oxygen-carrying
red blood cells.
Blood
transmission
• Blood is forced through an
intricate network of
glomerular capillary tufts
in the kidney.
• Water and waste products
flow out across the
glomerular filtration barrier
into the bowman’s space, to
be excreted as urine.
Causes & impact
of CKD
• The main causes of CKD in
developed countries are linked
to poor lifestyle choices.
• Hypertension and diabetes
silently damage the kidney
blood vessels.
• Heightened blood pressure in
the damaged capillaries can
lead to further damage and
kidney failure.
Diagnosis
• Patients with CKD
warning signs like
hypertension and
diabetes require close
monitoring.
• The estimated
glomerular filtration rate
(eGFR) can be
calculated from a blood
test and provides an
assessment of the
overall kidney function.
Treatment
• Haemodialysis and
peritoneal dialysis are
methods to help
remove toxins from the
blood when the kidneys
stop functioning.
• Another option for
patients may be kidney
transplantation.
Slide 5
Lifeblood
Website
Overview
Message from Roche
Medical expertise and artistic
inspiration combine to create
LIFEBLOOD:
• a clinically accurate and
visually stunning
illustration of chronic
kidney disease and renal
anaemia
• suitable for both medical
professionals and their
patients
How Lifeblood
was developed
• Digital slices of the body from
medical imaging devices are
built into 3D models of
tissues and organs.
• Enhanced and highlighted,
these detailed and
informative images explain
the complex processes of the
human body.
CKD & Anaemia
Anaemia is typically present with a
diagnosis of CKD –as the
diseased kidneys produce less of
the vital hormone erythropoietin
that’s needed to stimulate
production of red blood cells in the
bone marrow.
Loss of kidney
function
Reduced kidney function leads to:
• imbalance of volume and solutes
• anaemia
• bone disease
• metabolic acidosis
Kidney failure leads to uraemia –
the accumulation in the blood of
toxins usually excreted by the
kidney.
Common
causes of CKD
• hypertension
• obstructions in the urinary
tract (e.g. kidney stones)
• polycystic kidney disease
• glomerulonephritis
• recent urinary infections
• diabetes
• developmental
malformations
• autoimmune diseases
Marvel at our
Anatomy
• The kidneys maintain the
body’s balance, regulating
levels of water and salts.
• The kidneys are key to
vitality. When oxygen
levels are low they produce
erythropoietin, stimulating
the bone marrow to
produce oxygen-carrying
red blood cells.
Blood
transmission
• Blood is forced through an
intricate network of
glomerular capillary tufts
in the kidney.
• Water and waste products
flow out across the
glomerular filtration barrier
into the bowman’s space, to
be excreted as urine.
Causes & impact
of CKD
• The main causes of CKD in
developed countries are linked
to poor lifestyle choices.
• Hypertension and diabetes
silently damage the kidney
blood vessels.
• Heightened blood pressure in
the damaged capillaries can
lead to further damage and
kidney failure.
Diagnosis
• Patients with CKD
warning signs like
hypertension and
diabetes require close
monitoring.
• The estimated
glomerular filtration rate
(eGFR) can be
calculated from a blood
test and provides an
assessment of the
overall kidney function.
Treatment
• Haemodialysis and
peritoneal dialysis are
methods to help
remove toxins from the
blood when the kidneys
stop functioning.
• Another option for
patients may be kidney
transplantation.
Slide 6
Lifeblood
Website
Overview
Message from Roche
Medical expertise and artistic
inspiration combine to create
LIFEBLOOD:
• a clinically accurate and
visually stunning
illustration of chronic
kidney disease and renal
anaemia
• suitable for both medical
professionals and their
patients
How Lifeblood
was developed
• Digital slices of the body from
medical imaging devices are
built into 3D models of
tissues and organs.
• Enhanced and highlighted,
these detailed and
informative images explain
the complex processes of the
human body.
CKD & Anaemia
Anaemia is typically present with a
diagnosis of CKD –as the
diseased kidneys produce less of
the vital hormone erythropoietin
that’s needed to stimulate
production of red blood cells in the
bone marrow.
Loss of kidney
function
Reduced kidney function leads to:
• imbalance of volume and solutes
• anaemia
• bone disease
• metabolic acidosis
Kidney failure leads to uraemia –
the accumulation in the blood of
toxins usually excreted by the
kidney.
Common
causes of CKD
• hypertension
• obstructions in the urinary
tract (e.g. kidney stones)
• polycystic kidney disease
• glomerulonephritis
• recent urinary infections
• diabetes
• developmental
malformations
• autoimmune diseases
Marvel at our
Anatomy
• The kidneys maintain the
body’s balance, regulating
levels of water and salts.
• The kidneys are key to
vitality. When oxygen
levels are low they produce
erythropoietin, stimulating
the bone marrow to
produce oxygen-carrying
red blood cells.
Blood
transmission
• Blood is forced through an
intricate network of
glomerular capillary tufts
in the kidney.
• Water and waste products
flow out across the
glomerular filtration barrier
into the bowman’s space, to
be excreted as urine.
Causes & impact
of CKD
• The main causes of CKD in
developed countries are linked
to poor lifestyle choices.
• Hypertension and diabetes
silently damage the kidney
blood vessels.
• Heightened blood pressure in
the damaged capillaries can
lead to further damage and
kidney failure.
Diagnosis
• Patients with CKD
warning signs like
hypertension and
diabetes require close
monitoring.
• The estimated
glomerular filtration rate
(eGFR) can be
calculated from a blood
test and provides an
assessment of the
overall kidney function.
Treatment
• Haemodialysis and
peritoneal dialysis are
methods to help
remove toxins from the
blood when the kidneys
stop functioning.
• Another option for
patients may be kidney
transplantation.
Slide 7
Lifeblood
Website
Overview
Message from Roche
Medical expertise and artistic
inspiration combine to create
LIFEBLOOD:
• a clinically accurate and
visually stunning
illustration of chronic
kidney disease and renal
anaemia
• suitable for both medical
professionals and their
patients
How Lifeblood
was developed
• Digital slices of the body from
medical imaging devices are
built into 3D models of
tissues and organs.
• Enhanced and highlighted,
these detailed and
informative images explain
the complex processes of the
human body.
CKD & Anaemia
Anaemia is typically present with a
diagnosis of CKD –as the
diseased kidneys produce less of
the vital hormone erythropoietin
that’s needed to stimulate
production of red blood cells in the
bone marrow.
Loss of kidney
function
Reduced kidney function leads to:
• imbalance of volume and solutes
• anaemia
• bone disease
• metabolic acidosis
Kidney failure leads to uraemia –
the accumulation in the blood of
toxins usually excreted by the
kidney.
Common
causes of CKD
• hypertension
• obstructions in the urinary
tract (e.g. kidney stones)
• polycystic kidney disease
• glomerulonephritis
• recent urinary infections
• diabetes
• developmental
malformations
• autoimmune diseases
Marvel at our
Anatomy
• The kidneys maintain the
body’s balance, regulating
levels of water and salts.
• The kidneys are key to
vitality. When oxygen
levels are low they produce
erythropoietin, stimulating
the bone marrow to
produce oxygen-carrying
red blood cells.
Blood
transmission
• Blood is forced through an
intricate network of
glomerular capillary tufts
in the kidney.
• Water and waste products
flow out across the
glomerular filtration barrier
into the bowman’s space, to
be excreted as urine.
Causes & impact
of CKD
• The main causes of CKD in
developed countries are linked
to poor lifestyle choices.
• Hypertension and diabetes
silently damage the kidney
blood vessels.
• Heightened blood pressure in
the damaged capillaries can
lead to further damage and
kidney failure.
Diagnosis
• Patients with CKD
warning signs like
hypertension and
diabetes require close
monitoring.
• The estimated
glomerular filtration rate
(eGFR) can be
calculated from a blood
test and provides an
assessment of the
overall kidney function.
Treatment
• Haemodialysis and
peritoneal dialysis are
methods to help
remove toxins from the
blood when the kidneys
stop functioning.
• Another option for
patients may be kidney
transplantation.
Slide 8
Lifeblood
Website
Overview
Message from Roche
Medical expertise and artistic
inspiration combine to create
LIFEBLOOD:
• a clinically accurate and
visually stunning
illustration of chronic
kidney disease and renal
anaemia
• suitable for both medical
professionals and their
patients
How Lifeblood
was developed
• Digital slices of the body from
medical imaging devices are
built into 3D models of
tissues and organs.
• Enhanced and highlighted,
these detailed and
informative images explain
the complex processes of the
human body.
CKD & Anaemia
Anaemia is typically present with a
diagnosis of CKD –as the
diseased kidneys produce less of
the vital hormone erythropoietin
that’s needed to stimulate
production of red blood cells in the
bone marrow.
Loss of kidney
function
Reduced kidney function leads to:
• imbalance of volume and solutes
• anaemia
• bone disease
• metabolic acidosis
Kidney failure leads to uraemia –
the accumulation in the blood of
toxins usually excreted by the
kidney.
Common
causes of CKD
• hypertension
• obstructions in the urinary
tract (e.g. kidney stones)
• polycystic kidney disease
• glomerulonephritis
• recent urinary infections
• diabetes
• developmental
malformations
• autoimmune diseases
Marvel at our
Anatomy
• The kidneys maintain the
body’s balance, regulating
levels of water and salts.
• The kidneys are key to
vitality. When oxygen
levels are low they produce
erythropoietin, stimulating
the bone marrow to
produce oxygen-carrying
red blood cells.
Blood
transmission
• Blood is forced through an
intricate network of
glomerular capillary tufts
in the kidney.
• Water and waste products
flow out across the
glomerular filtration barrier
into the bowman’s space, to
be excreted as urine.
Causes & impact
of CKD
• The main causes of CKD in
developed countries are linked
to poor lifestyle choices.
• Hypertension and diabetes
silently damage the kidney
blood vessels.
• Heightened blood pressure in
the damaged capillaries can
lead to further damage and
kidney failure.
Diagnosis
• Patients with CKD
warning signs like
hypertension and
diabetes require close
monitoring.
• The estimated
glomerular filtration rate
(eGFR) can be
calculated from a blood
test and provides an
assessment of the
overall kidney function.
Treatment
• Haemodialysis and
peritoneal dialysis are
methods to help
remove toxins from the
blood when the kidneys
stop functioning.
• Another option for
patients may be kidney
transplantation.
Slide 9
Lifeblood
Website
Overview
Message from Roche
Medical expertise and artistic
inspiration combine to create
LIFEBLOOD:
• a clinically accurate and
visually stunning
illustration of chronic
kidney disease and renal
anaemia
• suitable for both medical
professionals and their
patients
How Lifeblood
was developed
• Digital slices of the body from
medical imaging devices are
built into 3D models of
tissues and organs.
• Enhanced and highlighted,
these detailed and
informative images explain
the complex processes of the
human body.
CKD & Anaemia
Anaemia is typically present with a
diagnosis of CKD –as the
diseased kidneys produce less of
the vital hormone erythropoietin
that’s needed to stimulate
production of red blood cells in the
bone marrow.
Loss of kidney
function
Reduced kidney function leads to:
• imbalance of volume and solutes
• anaemia
• bone disease
• metabolic acidosis
Kidney failure leads to uraemia –
the accumulation in the blood of
toxins usually excreted by the
kidney.
Common
causes of CKD
• hypertension
• obstructions in the urinary
tract (e.g. kidney stones)
• polycystic kidney disease
• glomerulonephritis
• recent urinary infections
• diabetes
• developmental
malformations
• autoimmune diseases
Marvel at our
Anatomy
• The kidneys maintain the
body’s balance, regulating
levels of water and salts.
• The kidneys are key to
vitality. When oxygen
levels are low they produce
erythropoietin, stimulating
the bone marrow to
produce oxygen-carrying
red blood cells.
Blood
transmission
• Blood is forced through an
intricate network of
glomerular capillary tufts
in the kidney.
• Water and waste products
flow out across the
glomerular filtration barrier
into the bowman’s space, to
be excreted as urine.
Causes & impact
of CKD
• The main causes of CKD in
developed countries are linked
to poor lifestyle choices.
• Hypertension and diabetes
silently damage the kidney
blood vessels.
• Heightened blood pressure in
the damaged capillaries can
lead to further damage and
kidney failure.
Diagnosis
• Patients with CKD
warning signs like
hypertension and
diabetes require close
monitoring.
• The estimated
glomerular filtration rate
(eGFR) can be
calculated from a blood
test and provides an
assessment of the
overall kidney function.
Treatment
• Haemodialysis and
peritoneal dialysis are
methods to help
remove toxins from the
blood when the kidneys
stop functioning.
• Another option for
patients may be kidney
transplantation.
Slide 10
Lifeblood
Website
Overview
Message from Roche
Medical expertise and artistic
inspiration combine to create
LIFEBLOOD:
• a clinically accurate and
visually stunning
illustration of chronic
kidney disease and renal
anaemia
• suitable for both medical
professionals and their
patients
How Lifeblood
was developed
• Digital slices of the body from
medical imaging devices are
built into 3D models of
tissues and organs.
• Enhanced and highlighted,
these detailed and
informative images explain
the complex processes of the
human body.
CKD & Anaemia
Anaemia is typically present with a
diagnosis of CKD –as the
diseased kidneys produce less of
the vital hormone erythropoietin
that’s needed to stimulate
production of red blood cells in the
bone marrow.
Loss of kidney
function
Reduced kidney function leads to:
• imbalance of volume and solutes
• anaemia
• bone disease
• metabolic acidosis
Kidney failure leads to uraemia –
the accumulation in the blood of
toxins usually excreted by the
kidney.
Common
causes of CKD
• hypertension
• obstructions in the urinary
tract (e.g. kidney stones)
• polycystic kidney disease
• glomerulonephritis
• recent urinary infections
• diabetes
• developmental
malformations
• autoimmune diseases
Marvel at our
Anatomy
• The kidneys maintain the
body’s balance, regulating
levels of water and salts.
• The kidneys are key to
vitality. When oxygen
levels are low they produce
erythropoietin, stimulating
the bone marrow to
produce oxygen-carrying
red blood cells.
Blood
transmission
• Blood is forced through an
intricate network of
glomerular capillary tufts
in the kidney.
• Water and waste products
flow out across the
glomerular filtration barrier
into the bowman’s space, to
be excreted as urine.
Causes & impact
of CKD
• The main causes of CKD in
developed countries are linked
to poor lifestyle choices.
• Hypertension and diabetes
silently damage the kidney
blood vessels.
• Heightened blood pressure in
the damaged capillaries can
lead to further damage and
kidney failure.
Diagnosis
• Patients with CKD
warning signs like
hypertension and
diabetes require close
monitoring.
• The estimated
glomerular filtration rate
(eGFR) can be
calculated from a blood
test and provides an
assessment of the
overall kidney function.
Treatment
• Haemodialysis and
peritoneal dialysis are
methods to help
remove toxins from the
blood when the kidneys
stop functioning.
• Another option for
patients may be kidney
transplantation.
Slide 11
Lifeblood
Website
Overview
Message from Roche
Medical expertise and artistic
inspiration combine to create
LIFEBLOOD:
• a clinically accurate and
visually stunning
illustration of chronic
kidney disease and renal
anaemia
• suitable for both medical
professionals and their
patients
How Lifeblood
was developed
• Digital slices of the body from
medical imaging devices are
built into 3D models of
tissues and organs.
• Enhanced and highlighted,
these detailed and
informative images explain
the complex processes of the
human body.
CKD & Anaemia
Anaemia is typically present with a
diagnosis of CKD –as the
diseased kidneys produce less of
the vital hormone erythropoietin
that’s needed to stimulate
production of red blood cells in the
bone marrow.
Loss of kidney
function
Reduced kidney function leads to:
• imbalance of volume and solutes
• anaemia
• bone disease
• metabolic acidosis
Kidney failure leads to uraemia –
the accumulation in the blood of
toxins usually excreted by the
kidney.
Common
causes of CKD
• hypertension
• obstructions in the urinary
tract (e.g. kidney stones)
• polycystic kidney disease
• glomerulonephritis
• recent urinary infections
• diabetes
• developmental
malformations
• autoimmune diseases
Marvel at our
Anatomy
• The kidneys maintain the
body’s balance, regulating
levels of water and salts.
• The kidneys are key to
vitality. When oxygen
levels are low they produce
erythropoietin, stimulating
the bone marrow to
produce oxygen-carrying
red blood cells.
Blood
transmission
• Blood is forced through an
intricate network of
glomerular capillary tufts
in the kidney.
• Water and waste products
flow out across the
glomerular filtration barrier
into the bowman’s space, to
be excreted as urine.
Causes & impact
of CKD
• The main causes of CKD in
developed countries are linked
to poor lifestyle choices.
• Hypertension and diabetes
silently damage the kidney
blood vessels.
• Heightened blood pressure in
the damaged capillaries can
lead to further damage and
kidney failure.
Diagnosis
• Patients with CKD
warning signs like
hypertension and
diabetes require close
monitoring.
• The estimated
glomerular filtration rate
(eGFR) can be
calculated from a blood
test and provides an
assessment of the
overall kidney function.
Treatment
• Haemodialysis and
peritoneal dialysis are
methods to help
remove toxins from the
blood when the kidneys
stop functioning.
• Another option for
patients may be kidney
transplantation.