Transcript Got Tissue? How Arizona Created a Statewide Virtual Tissue Bank

Got Tissue?
How Arizona Created a Statewide
Virtual Tissue Bank
Jim Matthews
Arizona Biomedical Research Commission
Jungdae Kokotov
5AM Solutions
July 27, 2010
www.5amsolutions.com
Webinar Technical Details
During discussion
time, “raise hand”
to speak
Type questions in advance; click send
Questions + answers appear in chat window
The Issue of Tissue
Biospecimens are at the core of discovery-oriented
scientific research.
Issues:
Collecting
Annotating
Finding
Obtaining
About ABRC
Arizona Biomedical
Research Commission
Research Program
Arizona Translational
Resource Network
(AzTransNet)
Funding
Funding
What Led Us Here
Anna Barker
The Tissue Issue
January 2007
Difficulty in
finding tissue for
research
January 2007
Our Process
The Solicitation
• RFP
• Responses
• Selection Criteria
• Deciding Factors
• 5AM Solutions
Our Vision
Sun Health Research Institute
Arizona Biospecimen Consortium
A Consortium of Institutional Partners
Governance Committee
Standards Committee
Business Model
Standardized Collection
Procedures
Commitments
Minimum Data Set
Governance Model
Federal Standards
Regulatory Compliance
Tissue Types/ Informed Consent
Agreements
Quality Control
Our Challenges
Partnership buy-in
Synchronicity of technology + governance
From Vision to Working System
Agile processes
Engaged stakeholders
5AM participation in Consortium meetings
Biolocator: High Level Workflow
11
How We Integrate – and Share – the Data
ABL
Automatic data pull
Periodic data import
Commercial
BioBanking
Solution
Custom
Application
CBM –
NCI’s caGrid
Share Information Over NCI’s caGrid
http://portal.training.cagrid.org/web/guest/home
Our Technical Challenges
Mapping data
Fields
Collection Date
Quality Rating
Specimen Type
Tumor Rating
Disease Type
Liquid Nitrogen
Paraffin Block
 Diverse systems, diverse data fields
 How do we find a common model…?
 NCI’s Common Biorepository Model
Date
Time
Tissue Type
Cancer Boolean
Lab Report Freetext
Values
 Diverse systems, diverse data values
 How do we find a common disease vocabulary…?
 SNOMED-CT
Malignant
Breast Cancer
Tumor of Breast
Breast Cancer Type 1
Susceptibility Protein
Breast
Carcinoma
254837009
https://demo.5amsolutions.com/tissuelocator-web/
ABRC’s Future Role in the Arizona Biomedical Consortium
Funding the ABL program
Demonstrating usefulness
Assisting institutional partners
Equipment
Personnel
Integration Support
Next Steps for the Arizona Biospecimen Consortium
Develop a Platform for Future Services
Cord blood bank
Cord blood patient registry
Trauma center data warehouse linkage
Expand our Partners + Participants
Phoenix Indian Medical Center
Phoenix VA
Others
Contact Us
James Matthews
Jungdae Kokotov
Deputy Director
Project Manager
Biolocator
Arizona Biomedical Resource
Commission
[email protected]
5AM Solutions
[email protected]
Arizona Biospecimen Locator Demo:
https://demo.5amsolutions.com/tissuelocator-web/
???
What else would you like to discuss – open discussion
of your questions, topics, concerns