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Cardiovascular
System: Putting
the Heart into
Histo
Mesothelium
Lecture 9, Slide 1
3
Layers
 Endocardium
 Myocardium
 Epicardium
L9, S2

Fibrous Trigone



L9, S2
Forms the base of
tissue from which the
valves are anchored
Separates atria from
ventricles
Atria and ventricle only
communicate through
the AV bundle
L9, S3
Epicardium




DFIACT
Adipose
Coronary vessels and
cardiac nerves
Externally lined by
mesothelium


Simple squamous
cells
Secrete serous fluid at
visceral and parietal
pericardium
M
Z
I
A
H
L9, S5
L9, S4
Myocardium
L9, S6
Endocardium
L9, S7

Inner layer



Middle layer


DCT with smooth
muscle
Subendocardial layer


Masson’s Trichrome
Simple squamous
epithelium and CT
Elastic lamina
Purkinje fibers
Continuous with
myocardium
L9, S11
Purkinje Fibers



Branches of the AV
bundle of His
Cardiac muscle
modified for
conducting impulses
Located in the
subendothelium
L9, S12



Hypertrophied cardiac muscle fibers
One or two nuclei centrally situated
Rich in glycogen and mitochondria
1
2
3


L9, S13


Tunica Intima
Internal Elastic
Membrane Tunica Media
External Elastic
Membrane
Tunica Adventitia
The Aorta: An Elastic Artery

Tunica Intima



Internal Elastic Membrane
Tunica Media


L9, S15


Reticular or Elastic fibers
SMCs connecting elastic
fibers
External Elastic Membrane
Tunica Adventitia



L9, S16
Endothelium and BM
Diffuse
Vasa vasorum
Nervi vascularus







A = Aorta
B = Vein
C = Artery A
D = Nerve
E = Brown adipose
F = White adipose
G = CT
F
B
C
G
D
E
L9, S17
Aorta
L9, S19

Weigert Stain of the
Elastic lamina
E. None of the above
Q1
A
B
D
C
L9, S4
L9, S6
Q2 and Q3
A
B
L9, S12