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Cardiovascular
System: Putting
the Heart into
Histo
Mesothelium
Lecture 9, Slide 1
3
Layers
Endocardium
Myocardium
Epicardium
L9, S2
Fibrous Trigone
L9, S2
Forms the base of
tissue from which the
valves are anchored
Separates atria from
ventricles
Atria and ventricle only
communicate through
the AV bundle
L9, S3
Epicardium
DFIACT
Adipose
Coronary vessels and
cardiac nerves
Externally lined by
mesothelium
Simple squamous
cells
Secrete serous fluid at
visceral and parietal
pericardium
M
Z
I
A
H
L9, S5
L9, S4
Myocardium
L9, S6
Endocardium
L9, S7
Inner layer
Middle layer
DCT with smooth
muscle
Subendocardial layer
Masson’s Trichrome
Simple squamous
epithelium and CT
Elastic lamina
Purkinje fibers
Continuous with
myocardium
L9, S11
Purkinje Fibers
Branches of the AV
bundle of His
Cardiac muscle
modified for
conducting impulses
Located in the
subendothelium
L9, S12
Hypertrophied cardiac muscle fibers
One or two nuclei centrally situated
Rich in glycogen and mitochondria
1
2
3
L9, S13
Tunica Intima
Internal Elastic
Membrane Tunica Media
External Elastic
Membrane
Tunica Adventitia
The Aorta: An Elastic Artery
Tunica Intima
Internal Elastic Membrane
Tunica Media
L9, S15
Reticular or Elastic fibers
SMCs connecting elastic
fibers
External Elastic Membrane
Tunica Adventitia
L9, S16
Endothelium and BM
Diffuse
Vasa vasorum
Nervi vascularus
A = Aorta
B = Vein
C = Artery A
D = Nerve
E = Brown adipose
F = White adipose
G = CT
F
B
C
G
D
E
L9, S17
Aorta
L9, S19
Weigert Stain of the
Elastic lamina
E. None of the above
Q1
A
B
D
C
L9, S4
L9, S6
Q2 and Q3
A
B
L9, S12