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African Capacity
Development needs
Alioune DIEYE, EDCTP-DCCC Chair
Consensus meeting of the EDCTP-II
Brussels, 27-28 September 2010
Overall goal
The programme objective is to
accelerate the development of
new or improved drugs,
microbicides, diagnostics and
vaccines against these
diseases, currently with a focus
on phase II and III clinical
trials and on sub-Saharan
Africa.
EDCTP II JPA
Activity areas
1. Networking; N/N, N/S
2. South Networking
3. Clinical trials
4. Capacity building in DC
5. Advocacy and Fundraising
6. Programme Management
7. Information management and
databases
Developing Countries Coordinating
Committee (DCCC)
Chairperson : Prof. Alioune DIEYE (Senegal)
Vice-Chairperson : Dr Veronique Penlap (Cameroon)
Second Vice-Chairperson: Prof. Nkandu Luo (Zambia)
Dr Martin Antonio (Ghana)
Dr Modest Mulenga (Zambia)
Dr. Jasper Ogwa-Okeng (Uganda)
Prof. Angelique Ndjoyi Mbiguino (Gabon)
Dr Abraham Alabi (Nigeria)
Prof. Mecky Matee (Tanzania)
Dr Issoufu Saadou(Benin)
Dr Omu Anzala (Kenya)
Dr Hulda Swai (Tanzania)
Representatives from: OCEAC, WAHO, WHO AFRO, SADEC
3 Main pillars
1. Human Resources
2. South –South Networking
3. Research Institutions and
Health services environments
Specific Capacity Development
objectives
• Upgrade sites including training for specific staff
• Training (Masters and PhD students) as well as
Postdoctoral and Senior Fellows
• Retention of highly skilled very senior scientists
and encouraging the return of those in the
Diaspora
• Improve compliance with internationally
accepted standards for ethical review, drug
regulatory authorities
• Support the establishment of regional nodes of
excellence, the development and site
characterisation studies.
What are the proposed
strategies to implement
the 3 pillars?
1. HUMAN RESOURCES:
TRAINING AND
FELLOWSHIPS
Human Resources :Training
• Staff working on clinical trial
sites: IT staff, Clinical Monitors,
Financial managers, Project
managers, personnel involved
with patients or patient material,
community representatives and
laboratory personnel.
Human Resources :
Fellowships
• Senior Fellowships
• Postdoctoral Fellowships: part of
the capacity development work package
of integrated projects
• Advanced Fellowship and
Mentorship for very senior
scientists
2. SOUTH-SOUTH
NETWORKING
South-South Networking
• Support the Regional Networks of
Excellence (NoEs):
Regional reference laboratories
Centres specialised in Data
management
• Support the development and site
characterisation studies:
 Lack of recent epidemiological data
3. RESEARCH INSTITUTIONS
AND HEALTH SERVICES
ENVIRONMENTS
Improvement of Research
Institutions and Health Services
environments
• Establishment and strengthening of
national ethical committees (NEC)
• Creation and strengthening of
Institutional Review Committees (IRC)
• Supporting the strengthening of
National Regulatory Bodies/Agencies in
Africa through collaboration with WHO
initiatives.
Improvement of Research
Institutions and Health Services
environments
• Sustaining adequate scientific
capacity of Institutions
(Infrastructure requirements)
• Promoting the strengthening of
Health services
 Research on the application of products in
health services and disease control
programmes, with studies on
pharmacovigilance, delivery or accessibility
and controlled community-based interventions
EDCTP public Consultancy:
The University of Oxford
There is a vast gap in capacity to run trials
between the developed and developing world.
Currently over 90% of trials conducting in
these regions are sponsored by northern
partners.
In practice this means that most of the
scientific input and thinking being conducted
by the sponsor and the trial sites merely
operate the study. Sites are not left with skills
to run their own programmes. Often capacity
building is attached to these studies as
window dressing.
Thank you!