Transcript Case 3 - nshealth.ca

Case 3
• 30 year old woman
• Visiting friend from out of province. Found
deceased in bed
• Some ethanol ingestion, but no drug use,
reported evening prior
• History of hypertension, no medications
• At autopsy:
– Cardiomegaly (550 grams) and left ventricular
hypertrophy (2.0 cm)
– Arteriolonephrosclerosis
Case 4
• 6 year old boy
• Presented to hospital with 2 hours of vomiting
• Vtach and hypotension during investigations,
cardiac arrest
• One week history occasional headaches and
two day history intermittent chest pain
• No known medical or family history
Chromogranin
S100
Synaptophysin
Inhibin
Case 5
• 23 day old infant female
• Presented with abnormal respirations and
became unresponsive
• Transported to IWK, never regained
consciousness
• Approximately 8 hours presentation to death
• Normal pregnancy and delivery, previously
healthy
• At autopsy:
– Well nourished and normally developed
– No injuries
– Subarachnoid staining, vascular congestion and
petechial hemorrhages, markedly friable
parenchyma
• Neuropathology consultation:
– Purulent exudate parieto-occipital region
– Perivascular cuffing monocytes and neutrophils,
focal endothelialitis
– Gram positive cocci, not paired
• Blood culture (post mortem):
– Streptococcus agalactiae, no other growth
• Mother GBS positive on prenatal screening
• No antibiotics given at delivery
Case 6
• 32 year old woman
• Witnessed sudden collapse
• No known medical history