Transcript Intro QALY & need assessment
Cost effectiveness as argument for reimbursement in prevention
• • • •
Jan J. v. Busschbach, Ph.D.
Erasmus MC
– Institute for Medical Psychology and Psychotherapy PO Box 1738 3000 DR Rotterdam +31 10 4087807 [email protected]
Psychotherapeutic centre 'De Viersprong’
– PO Box 7 4660 AA Halsteren + 31 164 632200 [email protected]
Presentations can be found at
– http://www.xs4all.nl/~jannetvb/busschbach/ 1
Health Economics
• •
Comparing different allocations
– Should we spent our money on » Wheel chairs » Screening for cancer » Preventing alcohol abuse – Comparing costs – Comparing outcome
Relate costs to outcome
– Cost per outcome 2
Car economics
• •
Should we spend our money on a
– Suzuki Alto 1.0
– BMW 316 – Comparing costs – Comparing outcome
Relate costs to outcome
– Cost per outcome – Cost per kilometer » Suzuki Alto 1.0
» BMW 316 3
Car league table
Car Suzuki Alto 1.0
Daihatsu Cuore 1.0
Hyundai Atos Multi 1.0
€ / Km 0.24
0.27
0.27
Car Hyundai Lantra 1.5
Opel Vectra 1.6
Citroën Xantia 1.8i
€ / Km 0.47
0.53
0.55
Renault Twingo 1.2 inj 0.28
Mazda 626 2.0
0.58
Daewoo Matiz 0.33
BMW 316 0.74
Cost per kilometre including gas, maintenance, debit, etc. Price level 2002.
Calculations based on over 2,5 years use and 40.000 km.
(Consumentenbond, Augustus 2003) 4
Health Economics
• •
Comparing costs
– Inside health care – Outside health care
Comparing outcome
– Life years – Quality of life » Quality Adjusted Life Years » QALYs 5
QALY league table
Intervention
GM-CSF in elderly with leukemia EPO in dialysis patients Lung transplantation End stage renal disease management Heart transplantation Didronel in osteoporosis PTA with Stent Breast cancer screening Viagra Treatment of congenital anorectal malformations
$ / QALY
235,958 139,623 100,957 53,513 46,775 32,047 17,889 5,147 5,097 2,778 6
Additional arguments in car economic
• • •
When people are facing the bad cost effectiveness of their own car...
Denial
– Validity and ad hoc arguments » My car is not on the list...
» I drive more kilometres...
» I drive a diesel...
The use additional arguments
– The sensation of driving – Beauty – Space – Prestige 7
Additional arguments in health care reimbursement
• •
If economics evaluation fails
– Reimbursement of lung transplantation – No reimbursement of Viagra
Denial
– Debate about the validity of the health economics » lung transplantation: not all cost of screening / waiting list should be included » Viagra: preferences for sex (erectile functioning) can not be measured in QALYs – Secondly, ad hoc arguments are used » lung transplantation: it is unethical to let someone die » Viagra: erectile dysfunction in old men is not a disease 8
Ad hoc arguments represents burden of disease
• •
Severity of illness
– Looking forwards » Prospective health – lung transplantation: it is unethical to let someone die » Rule of rescue » Necessity of care
Faire innings
– Looking backwards » Total health – Viagra: when you get older, erectile dysfunction is not longer considered a disease » You had you share of the cake » Does not apply for younger man 9
Combining “severity of illness” with “faire innings” (Elly Stolk)
Proportional short fall
Onychomycosis Osteoporosis Symptomatic BPH Hypertension High Cholesterol Arteriosclerosis COPD Pneumococcal pneumonia Pulmonary hypertension Non-Hodgkin Lymphoma 0.02
0.08
0.09
0.26
0.28
0.55
0.61
0.82
0.96
0.97
10
CE-ratio by burden of disease
11
Burden of disease and prevention
• •
Severity of illness
– The potential patient is not ill (yet) » Focuses on the patients that die now, not in the future » Discounting
Fair innings
– The future patients is still collecting his faire innings •
Burden of disease is not in favour of prevention
– Prevention has to be more cost effective than cure 12
Can we escape the negative influence of burden of disease?
• • •
Define conservative target population
– Flu vaccination is to prevent mortality in elderly » Not to prevent mobility – Alcohol abuse programs is not for the common men » Low burden of disease in normal life
Otherwise dilution of burden...
– Explains reimburcement when media focus on victims » meningitis vaccination
Different target as for cost effectiveness
– Cost effectiveness: treated population – Burden of disease: main target population 13
Conclusion
• • •
Cost effectiveness arguments exits next to other arguments The burden of disease argument is negative for prevention
– Prevention has to be more cost effective than cure
Focus burden of disease studies on those patient groups for who it really matters
– To prevent the erosion of the argument 14