Transcript Document

ميحرلا نمحرلا الله مسب

Simulation of Photon Beam Interaction with the ZUBAL Head Phantom

Presented by:

Mostafa Hossni El-Soubki

Plan-UNC-Image plotter

Outline 1. Preparing the phantom and Converting to MCNP using the MATLAB software 2. Commissioning the geometry 3. Dealing with MATLAB GI to view the output data.

4. Transfer the phantom to plan-UNC, and compare the same plan with MCNP 5. Conclusion 6. References.

Preparing the Phantom

• • Maximum number of cells allowed is 99999

(#cells x-axis * #cells y-axis* #cells z-axis)<99999

Preparing the Phantom

• The voxels outside the head have been excluded Fig-4 (By image-j)

Preparing the Phantom

• The slice matrix has to be resized Slice 23 after resizing from 59*40 to 50*37

Preparing the Phantom

• Material indexing has to be adjusted for MCNP.

Fig-5

Preparing the Phantom

Material # 1 2 3 4 5 6 71 72 10 75 76 77 78 79 16 17 Organ outside phantom skin brain spinal cord skull spine dens of axis jaw bone skeletal muscle lachrymal glands spinal canal hard palate cerebellum tongue pharynx esophagus Material # 86 23 24 27 92 30 31 100 105 107 114 120 122 123 126 Organ medulla oblongata fat blood pool bone marrow pons trachea cartilage uncus (ear bones) sinuses/mouth cavity optic nerve cerebral falx eye lens cerebral aqueduct teeth

Preparing the Phantom

Converting all slices to MCNP

Converting From material excel sheets to MCNP.

Validating the Geometry

Applied Beam:

• • •

SSD =100cm Field size = 5x5 cm2.

Photon Beam energy = 6 MV

Validation in a Water Phantom

Primary collimator

Voxel volume = 0.5*0.5*0.5 cm3 Phantom volume= 30* 30 * 30 cm3

Ion chambers Light mirror X-y jaws Fig-11 Blue is air.

Blue sky is water Light field reticle (MYLER)

Percent Depth Dose Comparison PDD% for 6mv LINAK 5x5 cm2 at 100cm SSD

100.000

90.000

80.000

70.000

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40.000

30.000

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10.000

0.000

0

dmax=1.5 cm

5 10 15

Fig-21

20 25 30 35 MCNP 5x5 cm2 6MV PDD% ion chamber 6mv 5x5 Diference

Percent Depth Dose Comparison

100.000

90.000

80.000

70.000

60.000

50.000

40.000

30.000

20.000

10.000

0.000

0

6mv PDD 5x5 cm2 100cm SSD dmax=1.5cm

5 10

Depth cm

15 Fig-24 20 25 MCNP 6MV 5x5 PDD % planUNC PDD Differnce

PDD Comparison

beam energy field size cm2 6MV depth cm PDD% dmax=1.5 cm ±ΔPDD 5*5 5*5 1.5

5 100 85 0.70

0.60

5*5 10*10 10*10 10*10 10 1.5

5 10 63.8

100 86.9

67.5

0.48

1.018

0.92

0.77

Beam Profile Comparison

-20 -15

6MV beam Profile for 5x5 cm2 at differnt depths

1.00

-10 -5 0.90

0.80

0.70

0.60

0.50

0.40

0.30

0.20

0.10

0.00

0

off axis cm

5 10 15 20 Profile at dmax 1.5cm

profile at 5cm depth profile at 10cm depth

Measured and Simulated Profile at 1.5cm Depth (Field Size 5x5 cm 2 )

-5 -4 -3 -2 100 90 80 70 60 50 40 30 20 10 -1 0 0

off axis

1 2 3 4 5 6MV measured profile% at dmax MCNP 6MV profile at dmax depth Difference %

Measured and Simulated Profile at 5 cm Depth (Field Size 5x5 cm 2 )

100.00

90.00

80.00

70.00

60.00

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20.00

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6MV measured profile% at 5cm depth MCNP 6MV profile 5 cm depth Diifernce % -5 -4 -3 -2 -1 0.00

0

off axis cm

1 2 3 4 5

Measured and Simulated Profile at 10 cm Depth (Field Size 5x5 cm 2 )

100.00

-5 -4 -3 -2 90.00

80.00

70.00

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of axis cm

1 2 3 4 5 6MV measured profile% at 10cm depth 6MV MCNP profile% at 10 cm depth Difference %

6 MV Beam Interaction with Head Phantom Applied Beam:

• • •

SSD =100 cm Field size =5x5 cm 2 Photon Beam energy = 6 Mev

Transverse Cross Section

Fig-25 slice-8 (MCNP MATLAB GUI)

Coronal Cross Section

Transfer the Phantom to Plan-UNC MCNP

converting to excel sheets

Plan-UNC

converting to dicom

Beam Setup of Head Phantom in Plan-UNC SSD = 100 cm at slice number 8.

Field size = 5 x 5 cm2.

Photon Beam energy = 6 Mev

Central PDD

PDD% for 6mv LINAK 5x5 cm2 at 100cm SSD for slice-8

100.000

90.000

80.000

70.000

60.000

50.000

40.000

30.000

20.000

10.000

0.000

0

Inhomogeneous region

2 4 6 8 10 12 14 16 18 MCNP slice-8 6MV 5x5 PDD % plan-UNC slice8 PDD Differnce

Fig-28 the inhomogeneous region in slice 8

Fig-27 Central PDD of slice-8 Skull bones at 2cm depth

Isodose Lines ISO-Dose levels: [ 0.98 0.95 0.9

0.7 0.5

]

Plan-UNC MCNP

Plan-UNC-Image plotter

MCNP surface dose distribution

Fig-30

Conclusions

• Validation of geometry – Good agreement in PDD in decay region – Need better agreement in dose profiles in penumbra region • There is disagreement between MCNP and Plan UNC in the inhomogeneous regions (transition from bone to soft tissue • Need for better quantitative methods to compare dose distribution in the phantom

References

• • •

Visual Basic 6 MSDN library.

Matlab7 Help.

http://noodle.med.yale.edu/phantom/get data.htm

(ZUBAL phantom).

Thank you