Transcript IV. Blood flow in a constriction

IV. Blood flow in a constriction
• On the enhanced Poiseuille-Fahraeus effect
25 mm
depth 25 mm
100 mm
Re=0.06
Enhanced cell free layer
@ 1000ml/hr in 40 cP
cell free layer
Trajectories of high concentration blood cells near the top, middle and bottom of the
channel with a flowrate of 1000ml/hr and a semi-circular constriction
0
100
200
Length in microns
300
400
0
Length in microns
20
40
60
80
100
120
140
cells adjacent to bottom of wall
cells in the middle
cells adjacent to the top of the wall
top channel wall
bottom channel wall
500
600
II. Dynamics in small capillaries:
train formation in 2D (longer range effects)
• Flow in Hele-Shaw channels: Train
formation
• Likely cause is hydrodynamic interactions
(analogous to deformable drops): under
study
• Relative velocity between the cell and the
fluid
• Unusual shape

Future experiments : contrast the
shapes of drops, vesicles and cells
Flow
100 mm
Depth = 4.5mm