Transcript SPEX SamplePrep Equipment Lineup

SPEX SamplePrep
Equipment Lineup
 Freezer/Mill
 Geno/Grinder
 Presses
 Mixer/Mill
 Shatterbox
 XRF accessories
© SPEX SamplePrep, Inc. 2008
Freezer/Mills ®
6770
6870
 The Ultimate Sample Preparation Technique
for Pulverizing “ Difficult ” Samples
 Grinding materials at low temperatures.
 Liquid Nitrogen –196°C
© SPEX SamplePrep, Inc. 2008
 Have difficult
samples to
prepare?
 You tried every
technique in your
laboratory and
nothing works?
 Feel that nothing in
this world will grind
your samples?
© SPEX SamplePrep, Inc. 2008
“Ungrindable” samples can be pulverized
Leaves, roots, stems, seeds (cotton, sunflower, corn)
Polymers, rubber, silicones
Fibers, hair, textiles
Skin, bone, muscle, cartilage, etc
Food products, paint chips, pharmaceuticals
Gums, resins, waxes
Electronic components
Tough food, feed materials (dog chews)
© SPEX SamplePrep, Inc. 2008
Before & After…
Leather
Corn
A Collection of our Before &
After Samples
Bone
© SPEX SamplePrep, Inc. 2008
 Spex SamplePrep freezer
mills are the only true
“Cryogenic Mills” on the
market for over 40 years.
 Utilized for grinding fresh
plant and animal tissue for
nucleic acids (RNA/DNA),
forensics, GMO analysis and
genetic research
 Useful tool for pharmaceutical
analysis, drug testing,medical
research, polymers and
plastics.
 RoHs/WEEE testing
© SPEX SamplePrep, Inc. 2008
 Cryogenic mills which chill
samples to liquid nitrogen
temperatures (-196C)
 Magnetically driven impactor is
the only moving part
 No mechanical linkages or
bearings to fail
 Grinding vials are sealed so
sample integrity is maintained
during grinding cycle
 Equip with speed control,
programmable timer, and safety
interlock.
 Sample sizes from 0.1g to 50g
© SPEX SamplePrep, Inc. 2008
 Integral LN reservoir maintains cryogenic temperatures
 Programmable LCD Touch Screen Controls
 Multiple User Memory Settings
 The only mill to grind samples in LN. This ensures optimum
sample brittleness for best results
 Has integral pre-cooling positions (reduced LN consumption,
safe storage of ground samples, no external chilling equipment
needed)
 Auto-fill option (6870 only)- time saving and increased safety
 Low cost vials with easy sample extraction-important for
forensic and pharma customers who need disposable vials
 Several vial options, micro vials, regular, mid size and large
© SPEX SamplePrep, Inc. 2008
Applications/where to sell
 Forensic Labs –DNA identification
 Medical Laboratories –genetic research, disease prevention
 Hospital Labs – For genetic screening (oncology, etc)
 Agricultural Labs – For crop development and GM testing
 Agricultural Veterinary Labs – For livestock breeding and
health
 Archaeology Labs – Ancient DNA Extraction
 Public Health and Environmental Monitoring Laboratories
 Contract/commercial testing labs QC of manufactured
goods
 Electronics Companies – grinding electronic components
© SPEX SamplePrep, Inc. 2008
Freezer mills 6770 & 6870
Applications and Markets
Other new markets and opportunities
 Electronics companies - grinding soft metals (Aluminium,
Zinc)
 Pharmaceutical companies – grinding capsules and whole
tablets
 Dentistry - grinding amalgams, resins
 Food safety– toxicity testing
 Phthalates in plastics - new regulations
© SPEX SamplePrep, Inc. 2008
New CPSC Guidelines for Determination
of Phthalates in Plastics
 Consumer Product Safety Commission (CPSC)
standard operating procedure for determining
phthalates in plastics in children’s toys
 Operating procedure recommends the use of
cryogenic grinding to prepare samples
– Cryogenic grinding can pulverize samples
down to a fine powder of less than 500 microns
– Creates homogenous sample with a larger
surface area improving the extraction process.
© SPEX SamplePrep, Inc. 2008
Freezer/Mill in Action
6770 in CSI Miami
(Season 7 Ep. 2)
Used in studies of
Moon Rock
© SPEX SamplePrep, Inc. 2008
Geno/Grinder ®
2010
 The 2010 Geno Grinder was specifically
designed for Pioneer Hybrid International
 “A World Leader in genetic crop science”.
 The Geno/Grinder provides a mechanism
for efficient cell disruption of plant and
animal tissue for the isolation of nucleic
acids (RNA/DNA), enzymes, yeast and
proteins.
 The versatile sample clamping
mechanism can also hold micro-tubes,
racked tubes, specially designed 5 ml
vials, 15ml and 50 ml standard conical
tubes using the optional large capacity
clamp adapter.
© SPEX SamplePrep, Inc. 2008
NEW FEATURES
 Modern, streamlined look
 Smaller footprint
 Lighter
 LCD Display
 Improved reliability of wear parts
 Unique true vertical action – ensures complete
sample processing.
 Sample clamp accepts multiple micro titer-plates,
various vials from 0.6ml to 50ml vials - wide
application range.
 Adjustable speed control and timer (with
countdown display) for optimum results.
 Wide range of cryogenic accessories
 Wide range of grinding media
© SPEX SamplePrep, Inc. 2008
•Kryo-Tech®
accessories
 Cryo-Station
– A holding station for temperature sensitive
samples such as proteins and pesticides
 Cryo-Adapter
– A single piece of extruded aluminium to be
chilled and then inserted into a 2210 96-well
Titer Plate
 CryoBlocks
– Aluminium blocks designed to hold samples
for chilling in the Cryo-station. Cryo-Blocks
come in a variety of holding sizes including
0.6 mL & 2.0 mL PCR tube capacity.
 Cryovials
– PC and PE centrifuge tubes specifically
designed to resist breaking at low
temperatures. Ideal for grinding temperature
sensitive samples.
© SPEX SamplePrep, Inc. 2008
2010 Geno/Grinder®
2000 Geno/Grinder Applications
 Rapid preparation of multiple
samples for PCR sampling
 Fast disruption to allow
extraction of Nucleic acids
 High-throughput in a 96-well
format and various other
formats up to twelve 50mL
centrifuge tubes
 Lysing of bacterial cells
 DNA screening for disease
control
 Pesticide analysis
© SPEX SamplePrep, Inc. 2008
Where to Sell
Markets
 Basically – any institution using high throughput
DNA sample processing
 Plant and Animal development companies
 Agricultural and public health labs (disease
screening).
 Pesticide residues
 Micro toxins
Look for synergy! - DNA sequencing equipment,
Cell washing equipment, Microplate sealing
equipment.
© SPEX SamplePrep, Inc. 2008
2010 Geno/Grinder®
QuEChERS Method
Quick
Easy
Cheap
Effective
Rugged
Safe
•Plant tissue from Fruits and
Vegetables are homogenized
and mixed with QuEChERS
reagents using Geno/Grinder &
ceramic grinding media
•Can be homogenized at room
temperature or with Kryo-Tech®
accessories
•Up to 16 x 50ml vials can be
processed simultaneously
•Increases pesticide yields
•Improves reproducibility
•Used by FDA
© SPEX SamplePrep, Inc. 2008
Geno/Grinder – Sales Focus
 Primarily high-throughput users
– Capital costs are easily countered by time savings
 Multiple sample format flexibility
– Appeals to a broad spectrum of users and applications
 Pedigree of existing users
– Name drop – use the reference list to its full benefit
 Profile of existing users
– Look for similarities between current and potential users
Example Customers:
Danish Institute of Agricultural Science | Planta, Germany
Pioneer, France | Monsanto, UK | Syngenta, UK
Rijk Zwaan, Netherlands | Enza Zaden, Netherlands
Pioneer Hybrid, USA | Du Pont, USA | Promega, USA
US Dept. of Agriculture | Aventis Crop Science, USA| Merck, USA
© SPEX SamplePrep, Inc. 2008
X-Press ® & Bench-Press ®
3635/3628
Presses
3635
3628
Force
35 ton
25 ton
Control
Automatic,
Programmable
Air-Actuated,
Manual Control
Die Sets
13mm, 31mm,
35mm, 40mm
13mm, 31mm,
35mm, 40mm
© SPEX SamplePrep, Inc. 2008
3635 X-Press®
 New anodized look with the same
rugged reliability
 The X-Press is a 35 ton fully
automated hydraulic press used for
spectroscopic techniques requiring
samples in the form of round, flatsurfaced discs, most commonly XRF
 SPEX SamplePrep presses and dies
are sophisticated in design, but
functionally simple and provide years
of maintenance-free operation.
© SPEX SamplePrep, Inc. 2008
3635 X-Press®
Features and Benefits
 Now featuring a programmable
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LCD touch screen
Fully Programmable - Final
pressure desired, time to hold at
final pressure, and intervals to
return back to zero pressure
Typical pressing cycle is less than
two minutes
A safety interlock and automatic
pump shut-off safety valve
ensure safe operation
Compact, bench top operation
Accepts all competitors die sets
CE marked
© SPEX SamplePrep, Inc. 2008
3628 Bench-Press ®
 The 3628 Bench-Press is an
air-actuated, manually
controlled 25-ton laboratory
press.
 This Bench-Press is compact
 Very simple controls
 It includes a safety door with
interlock, CE-marked
 Accepts most other “ standalone” pellet dies.
 Good for spark free
environments
© SPEX SamplePrep, Inc. 2008
X-Press ® & 3628
Where to Sell
 Users of XRF instruments
 Universities – notably Geology
Depts.
 Cement manufacturing
 Any industrial facility requiring
analysis or processing pelletized
samples
 Markets and customers similar to
Shatterbox and Mixer mills
Look for Synergy ! (work with XRF
supplier offices / sales reps in
your regions)
© SPEX SamplePrep, Inc. 2008
Mixer/Mill
5100
8000M
8000D
Pulverizing & Blending
Model
Mill Type
5100
Mixer/Mill
Motion
Typical Sample Size (grams)
0.1 – 2.0
Can hold up to 3
small vials
8000M
Mixer/Mill
2 - 10
8000D
Mixer/Mill
2- 10
(Two Samples can be run
simultaneously)
20 g sample using two vials
8530
Shatterbox
10 - 200
© SPEX SamplePrep, Inc. 2008
8000M Mixer/Mill
 Efficient laboratory mill for
pulverizing hard, brittle samples
 Often described as a shaker mill
or high-energy ball mill
 Capable of rapidly reducing
solids to analytical fineness or
blending a wide range of
powders
 Effective for mechanical
alloying, well documented in
literature “SPEX Mill”
 Extended run times
 Membrane control panel
 Built in Fan for cooling
© SPEX SamplePrep, Inc. 2008
Mixer/Mills
Features & Benefits
Mixer/Mill is only ball mill that can
be used for efficient Mechanical
alloying.
Figure of Eight motion has been
proven to be more efficient than
side-to-side or planetary motion
found in other mills
Extremely robust
Large range of grinding vial
materials and size
Competitively priced
© SPEX SamplePrep, Inc. 2008
Mixer/Mills
Where to Sell
 Universities, geology ,materials science,
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engineering departments
Industrial laboratories - cement, slag,
ceramics, catalysts
Pharmaceutical companies (Blending,
polymers)
Rock Labs
Electronics (mechanical alloying)
Petroleum companies
Corn milling method G-11 Hexane
extraction method
http://corn.org/methods/G-11.pdf
© SPEX SamplePrep, Inc. 2008
Shatterbox ®
8530
Shatterbox ® 8530
 The Shatterbox is the most
popular “swing mill” in America
 It is the most efficient way to
grind brittle samples to analytical
fineness
 The Shatterbox swings a dish-
shaped grinding container with
a puck and ring, in a tight highspeed circle
 Fast grinding times
© SPEX SamplePrep, Inc. 2008
Shatterbox ® 8530
Features & Benefits
 Resultant particle size well below
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200 mesh; with proper grinding
aid, less then 10 microns
Wide choice of grinding
container material and size
Clamp requires only moderate
hand pressure to secure grinding
dish and is adjustable to secure
containers of different heights
Vial transporter available
Soundproof enclosure, variablerange electronic timer, lockable
casters & safety interlock system
Membrane control panel
resistant to airborne particles
© SPEX SamplePrep, Inc. 2008
Shatterbox ® 8530
Where to Sell
 Same markets as mixer/mills
 Notably mining operations
(prefer larger samples sizes)
 Pharmaceuticals, dried marsh
grass, and many other materials
© SPEX SamplePrep, Inc. 2008
XRF Accessories
 Spec-Caps ®
• Shallow, thin-walled aluminum cups routinely
used to produce pressed-powder sample
discs for XRF. Sizes available for all die sets.
 X-Cells for XRF Liquid Samples
• Patented closed X-Cell design prevents
spillage in inverted XRF spectrometers. Sizes
to fit most instruments.
 Thin Film Windows for XRF
• Necessity for X-Cell liquid sample cell, serving
as a the sample window. Different types
available based on sample characteristics.
Eg Mylar ®
© SPEX SamplePrep, Inc. 2008
XRF Accessories
Features & Benefits
• Provide a high profit margin and continuous
revenue stream
• Let users have samples – we can provide
sample packs for trial with key potential users
• Look for synergy with XRF instrument
manufacturers & suppliers
• Bulk quantities available for lower price
© SPEX SamplePrep, Inc. 2008
Thanks for your attention
© SPEX SamplePrep, Inc. 2008