Transcript Cholingeric Agonist Practice Questions - obsidian

Cholingeric Agonist Practice
Questions
Pretest question
• The enzyme that is inhibited by
echothiophate iodide is
• a. Tyrosine hydroxylase
• b. Acetylcholinesterase (AChE)
• c. Catechol-O-methyltransferase (COMT)
• d. Monoamine oxidase (MAO)
• e. Carbonic anhydrase
Pretest question
• The reversible cholinesterase inhibitor
indicated in the treatment of
Alzheimer’s disease is
• a. Tacrine
• b. Edrophonium
• c. Neostigmine
• d. Pyridostigmine
• e. Ambenonium
Pretest question
• All of the following drugs are used topically in
the treatment of chronic wide-angle glaucoma.
Which of these agents reduces intraocular
pressure by decreasing the formation of the
aqueous humor?
• a. Timolol
• b. Echothiophate
• c. Pilocarpine
• d. Isofluorphate
• e. Physostigmine
Pretest Question
• The cholinomimetic drug that is useful
for treating postoperative abdominal
distention and gastric atony is
• a. Acetylcholine (ACh)
• b. Methacholine
• c. Carbachol
• d. Bethanechol
• e. Pilocarpine
Pretest question
Pralidoxime chloride is a drug that
• a. Reduces the vesicular stores of catecholamines in
adrenergic and dopaminergic neurons
• b. Blocks the active transport of choline into cholinergic
neurons
• c. Reactivates cholinesterases that have been inhibited by
organophosphate cholinesterase inhibitors
• d. Stimulates the activity of phospholipase C with
increased formation of inositol
• triphosphate
• e. Inhibits the reuptake of biogenic amines into nerve
terminals
Pretest Question
• The cholinesterase inhibitor that is used
in the diagnosis of myasthenia gravis is
• a. Edrophonium chloride
• b. Ambenonium chloride
• c. Malathion
• d. Physostigmine salicylate
• e. Pyridostigmine bromide
Pretest Question
• Of the following effects, which is not elicited by
activation of the parasympathetic nervous
system?
• a. Decreased heart rate
• b. Increased tone of longitudinal smooth
muscles of the intestine
• c. Contraction of skeletal muscles
• d. Contraction of the detrusor of the urinary
bladder
• e. Secretion of fluid from the lacrimal glands
Pretest Question
• Which one of these drugs are used in
Glaucoma?
• a. Pilocarpine
• b. Methylphenidate
• c. Propranolol
• d. Ritodrine
• e. Phenoxybenzamine
Pretest Question
Practice Question
Which of the following would not be
expected as a sign of cholinesterase
inhibitor-insecticide poisoning.
A. Mydriasis
B. Increased Salivation
C. Increased bowel sounds
D. Urinary urgency
E. Skeletal muscle spasms  Paralysis
Practice Question
In the previous question, what would be
the treatment for this patient?
A. Atropine and epinephrine
B. Epinephrine and Isoproterenol
C. Norepinephrine and Propranolol
D. Atropine and Praxilodime
E. Prolidoxine and Propanolol
Practice Question
Which of the following drugs can be
used to reduce IOP in treatment of
Glaucoma?
A. Pilocarpine
B. Azetozelomide
C. Neostigmine
D. Timolol
E. All of the above
Practice Question
• Which of the following cholinesterase
inhibitors has the shortest duration of
action?
A.Neostigmine
B. Phyostigmine
C. Edrophonium
D.Echothiophate
E. Trimethaphan