Transcript Type1 Diabetes - Blackpool Teaching Hospitals NHS

Past, Present and the Future
Rabin Mohanty
Consultant Paediatrician
Blackpool
TYPE1 DIABETES
Before Insulin
JL on 12/15/22 and 2 mos later
• Before insulin was discovered in 1921,
everyone with type 1 diabetes died
within weeks to years of its onset
Impact Of Insulin On
Life Expectancy By The 1940’s
Age at start
of diabetes
50
30
10
Avg. age of
death in 1897
58.0
34.1
11.3
Avg. age of
death in 1945
65.9
60.5
45.0
Years Gained
8
26
34
Manufactured
insulin,
'Iletin',
United States,
1923
Newer
insulin
pens
1960s
1st
generation
of insulin
pumps
Modern
Insulin Pump
Tandem’s t:slim insulin pump
What is an Artificial Pancreas?
Islet Cell Transplantation
Is Diabetes Curable?
 Implantable Insulin Pumps
 Islet Cell Transplant
 Gene Therapy
 Stem Cell
 Vaccine
 Newer Drugs
Blackpool Paediatric Diabetes
Service
 140 children
 4 children on insulin pumps( 2 moved)
 4 new children on pumps soon
 CGMS monitoring
 50% on Basal Bolus
 HbA1c falling
 Less complications